2021
The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer
Wang Z, Xiao R, Huang J, Qin X, Hu D, Guo E, Liu C, Lu F, You L, Sun C, Chen G. The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer. Microbial Ecology 2021, 84: 302-313. PMID: 34405250, DOI: 10.1007/s00248-021-01800-0.Peer-Reviewed Original ResearchConceptsLocally advanced cervical cancerLocally advanced cervical cancer patientsPlatinum-based chemotherapy responseAdvanced cervical cancerCervical cancerChemotherapy responseAlpha diversityVaginal microbiotaVaginal samplesCC patientsVaginal microbiomeHealthy controlsPredicting neoadjuvant chemotherapy responsePlatinum-resistant patientsNeoadjuvant chemotherapy responseAssociated with platinum-based chemotherapy responseCervical cancer patientsVaginal microbiota diversityNeoadjuvant chemotherapyHPV infectionBeta diversityBacteroides genusChemotherapy effectCancer patientsBacteroides abundance
2018
Differences in the fecal microbiota of neonates born at home or in the hospital
Combellick JL, Shin H, Shin D, Cai Y, Hagan H, Lacher C, Lin DL, McCauley K, Lynch SV, Dominguez-Bello MG. Differences in the fecal microbiota of neonates born at home or in the hospital. Scientific Reports 2018, 8: 15660. PMID: 30353125, PMCID: PMC6199260, DOI: 10.1038/s41598-018-33995-7.Peer-Reviewed Original ResearchConceptsHospital-born infantsTime of birthPro-inflammatory gene expressionBreast fed neonatesInfants 1 monthLong-term health implicationsHuman colon epithelial HT-29 cellsDay of birthVaginal swab samplesMonths of ageLower BacteroidesMaternal antibioticsNeonate's microbiomeNeonatal microbiomeVaginal sourcesHT-29 cellsWater birthVaginal microbiotaIntestinal microbiotaDay 1Vaginal samplesHospitalInfantsFecal microbiotaBabiesEvaluation of different mucosal microbiota leads to gut microbiota-based prediction of type 1 diabetes in NOD mice
Hu Y, Peng J, Li F, Wong FS, Wen L. Evaluation of different mucosal microbiota leads to gut microbiota-based prediction of type 1 diabetes in NOD mice. Scientific Reports 2018, 8: 15451. PMID: 30337545, PMCID: PMC6193974, DOI: 10.1038/s41598-018-33571-z.Peer-Reviewed Original ResearchConceptsType 1 diabetesWeeks of ageGut microbiotaNOD miceVaginal microbiotaAuto-reactive T cellsNon-obese diabetic (NOD) micePeripheral blood mononuclear cellsInsulin-producing beta cellsFemale NOD miceProgressive autoimmune diseaseOnset of diabetesBlood mononuclear cellsDifferent mucosal sitesT1D developmentDiabetes onsetMucosal sitesDiabetes developmentDiabetic miceAutoimmune diseasesComposition of microbiotaMononuclear cellsT cellsMucosal microbiotaAdult mice
2015
Cervicovaginal Microbiota: Simple Is Better
Gopinath S, Iwasaki A. Cervicovaginal Microbiota: Simple Is Better. Immunity 2015, 42: 790-791. PMID: 25992855, DOI: 10.1016/j.immuni.2015.05.006.Peer-Reviewed Original Research
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