2024
Baseline characteristics and associated factors for hypertension in children with chronic kidney disease: results from the Korean Cohort Study for Outcome in Patients with Pediatric Chronic Kidney Disease study
Song J, Lee K, Shin J, Kang H, Ahn Y, Baek H, Cho M, Jung J, Lee J, Cho H, Han K, Park E, Yang E, Kim S. Baseline characteristics and associated factors for hypertension in children with chronic kidney disease: results from the Korean Cohort Study for Outcome in Patients with Pediatric Chronic Kidney Disease study. Kidney Research And Clinical Practice 2024 PMID: 39445345, DOI: 10.23876/j.krcp.24.006.Peer-Reviewed Original ResearchComplication of chronic kidney diseaseChronic kidney diseaseDiastolic hypertensionHigh left ventricular mass indexKidney diseaseLeft ventricular mass indexKorean Cohort Study for OutcomePatients aged <Ventricular mass indexFactors associated with hypertensionMultiple logistic regression analysisPediatric nephrology centersUrine protein/creatinine ratioChronic Kidney Disease studyLogistic regression analysisCross-sectional studyAssociated with various factorsBaseline characteristicsProtein/creatinine ratioNephrology centersSystolic hypertensionClinical dataMass indexCohort studyKidney Disease studyDiffering associations of PM2.5 exposure with systolic and diastolic blood pressures across exposure durations in a predominantly non-Hispanic Black cohort
Luo J, Jones R, Jin Z, Polonsky T, Kim K, Olopade C, Pinto J, Ahsan H, Aschebrook-Kilfoy B. Differing associations of PM2.5 exposure with systolic and diastolic blood pressures across exposure durations in a predominantly non-Hispanic Black cohort. Scientific Reports 2024, 14: 20256. PMID: 39217205, PMCID: PMC11366009, DOI: 10.1038/s41598-024-64851-6.Peer-Reviewed Original ResearchConceptsEffects of PM2.5 exposurePM2.5 exposureDiastolic blood pressureAssociations of PM2.5Associated with isolated diastolic hypertensionEnvironmental health researchPM2.5 exposure levelsBlack cohortBlood pressureHigh blood pressureHealth researchCVD outcomesPotential confoundersSystolic-diastolic hypertensionAssociation magnitudeMixed effects modelsElevation of SBPDiastolic hypertensionIsolated systolic hypertensionSBPEffects modelAssociationDBPSystolic hypertensionCohort
2022
Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial
Wang SY, Hanna JM, Gongal P, Onuma O, Nanna MG. Choice of antihypertensive agent in isolated systolic hypertension and isolated diastolic hypertension: A secondary analysis of the ALLHAT trial. American Heart Journal 2022, 254: 30-34. PMID: 35932912, PMCID: PMC10908340, DOI: 10.1016/j.ahj.2022.07.006.Peer-Reviewed Original ResearchConceptsDiastolic hypertensionSystolic hypertensionAntihypertensive agentsSecondary analysisPrevent Heart Attack TrialBroad treatment recommendationsDifferent antihypertensive agentsUse of chlorthalidoneLipid-lowering treatmentHeart Attack TrialCoronary heart diseaseCause mortalityPrimary outcomeAttack TrialALLHAT trialHeart diseaseTreatment recommendationsHypertensionPatientsTrialsAntihypertensivesAmlodipineLisinoprilStrokeAgents
2021
Is Isolated Diastolic Hypertension an Important Phenotype?
Romero CA, Tabares AH, Orias M. Is Isolated Diastolic Hypertension an Important Phenotype? Current Cardiology Reports 2021, 23: 177. PMID: 34657205, PMCID: PMC8753786, DOI: 10.1007/s11886-021-01609-w.Peer-Reviewed Original ResearchConceptsNarrow pulse pressureDiastolic hypertensionCardiovascular riskPulse pressureLong-term cardiovascular riskRecent FindingsRecent guidelinesHypertension subgroupIDH definitionsIDH prevalenceHypertensive patientsYounger patientsRisk stratificationEpidemiological characteristicsTherapeutic decisionsPharmacological interventionsHypertension phenotypesCutoff levelHypertensionImportant subgroupPatientsPathophysiologyRiskSubgroupsIDHLong term
2019
Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project
Mahajan S, Zhang D, He S, Lu Y, Gupta A, Spatz ES, Lu J, Huang C, Herrin J, Liu S, Yang J, Wu C, Cui J, Zhang Q, Li X, Nasir K, Zheng X, Krumholz HM, Li J, Dong Z, Jiang B, Zhang Y, Liu Y, Meng Y, Xi Y, Tian Y, Fu Y, Liu T, Yan S, Jin L, Wang J, Xu X, Xing X, Zhang L, Fang X, Xu Y, Xu C, Fan L, Qi M, Qi J, Li J, Liu Q, Feng Y, Wang J, Wen H, Xu J, He J, Jiang C, Yang C, Yu Y, Tashi Z, Hu Z, Zhang J, Li X, Ma S, Ma Y, Huang Y, Zhang Y, Shen J. Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project. Journal Of The American Heart Association 2019, 8: e012954. PMID: 31566101, PMCID: PMC6806046, DOI: 10.1161/jaha.119.012954.Peer-Reviewed Original ResearchConceptsMillion Persons ProjectPrior cardiovascular eventsBody mass indexAntihypertensive medicationsDiastolic hypertensionCardiovascular eventsDiabetes mellitusMass indexIsolated diastolic hypertensionDiastolic blood pressureSelf-reported diagnosisTreatment of peoplePersons ProjectBlood pressureTreatment patternsHypertensionLeast collegeHigher likelihoodMellitusMedicationsPrevalenceTreatmentDiagnosisSubstantial numberCurrent use
2013
Hemodynamic circulatory patterns in young patients with predominantly diastolic hypertension
Romero CA, Alfie J, Galarza C, Waisman G, Peixoto AJ, Tabares AH, Orias M. Hemodynamic circulatory patterns in young patients with predominantly diastolic hypertension. International Journal Of Cardiology Cardiovascular Risk And Prevention 2013, 7: 157-162. PMID: 23403215, DOI: 10.1016/j.jash.2013.01.001.Peer-Reviewed Original ResearchConceptsSystemic vascular resistanceStroke volume indexDiastolic hypertensionCardiac indexHemodynamic patternsHeart rateTotal arterial compliance indexAmbulatory blood pressure monitoringHigher systemic vascular resistanceNormal systemic vascular resistanceArterial compliance indexLow cardiac indexHigher cardiac indexBlood pressure monitoringSVR groupVascular resistanceYounger patientsBlood pressureHypertensive individualsHypertension patientsPathophysiologic mechanismsMean agePulse pressureHypertensionPressure monitoring
2010
Hypothesis: It Is Time to Reconsider Phenotypes in Hypertension
Orias M, Tabares AH, Peixoto AJ. Hypothesis: It Is Time to Reconsider Phenotypes in Hypertension. Journal Of Clinical Hypertension 2010, 12: 350-356. PMID: 20546376, PMCID: PMC8673086, DOI: 10.1111/j.1751-7176.2010.00266.x.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2007
Association of ACE genotype and predominantly diastolic hypertension: a preliminary study
Jiménez PM, Conde C, Casanegra A, Romero C, Hugo Tabares A, Orías M. Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. Journal Of The Renin-Angiotensin-Aldosterone System 2007, 8: 42-44. PMID: 17487825, DOI: 10.3317/jraas.2007.006.Peer-Reviewed Original ResearchConceptsPDH patientsDiastolic hypertensionBlood pressureGenotype distributionACE I/D polymorphismAngiotensin-converting enzyme polymorphismACE genotype DDAngiotensin II activityNormotensive control individualsCardiovascular risk factorsHigher plasma ACE levelsSystolic blood pressurePlasma ACE levelsChi-square testMmHg systolicEssential hypertensionPeripheral resistanceNormotensive controlsACE genotypeACE levelsRisk factorsDD genotypeD polymorphismHypertensionPatients
2003
P-118: Association of the DD ACE polymorphism and predominantly diastolic hypertension
Orias M, Jimenez P, Conde C, Tabares A. P-118: Association of the DD ACE polymorphism and predominantly diastolic hypertension. American Journal Of Hypertension 2003, 16: 81a-82a. DOI: 10.1016/s0895-7061(03)00284-x.Peer-Reviewed Original ResearchAmbulatory blood pressure monitoringDiastolic hypertensionACE polymorphismHg diastolic blood pressureAngiotensin II activityNormotensive control individualsCardiovascular risk factorsDiastolic blood pressureBlood pressure monitoringPDH patientsHg systolicHypertensive patientsBlood pressureEssential hypertensionNormotensive controlsPeripheral resistanceACE genotypeRisk factorsDD genotypeHypertensionPressure monitoringPatientsControl individualsGenotype variantsSystolic ratio
2000
Pulse pressure and risk for myocardial infarction and heart failure in the elderly
Vaccarino V, Holford T, Krumholz H. Pulse pressure and risk for myocardial infarction and heart failure in the elderly. Journal Of The American College Of Cardiology 2000, 36: 130-138. PMID: 10898424, DOI: 10.1016/s0735-1097(00)00687-2.Peer-Reviewed Original ResearchConceptsCongestive heart failureCoronary heart diseaseSystolic blood pressureCardiovascular end pointsDiastolic blood pressurePulse pressureBlood pressureEnd pointHeart failureIndependent predictorsOverall mortalityIncidence of CHFIncidence of CHDEffect of PPElevated systolic blood pressureCurrent hypertension guidelinesIncident CHF eventsCHD risk factorsCurrent medication useIncident CHD eventsPowerful independent predictorBlood pressure parametersBlood pressure variablesElevated pulse pressureDiastolic hypertension
1996
Cocaine-abusing Parturients Undergoing Cesarean Section
Kain Z, Mayes L, Ferris C, Pakes J, Schottenfeld R. Cocaine-abusing Parturients Undergoing Cesarean Section. Anesthesiology 1996, 85: 1028-1035. PMID: 8916819, DOI: 10.1097/00000542-199611000-00010.Peer-Reviewed Original ResearchConceptsCocaine-abusing parturientsCesarean section deliverySection deliveryCesarean sectionCocaine useOperative blood lossDiastolic blood pressureDiastolic hypertensionPeripartum eventsAbruptio placentaeMaternal morbidityObstetric outcomesCohort studyFetal distressBlood lossBlood pressureIndependent predictorsVentricular dysrhythmiasAnesthetic implicationsEpidural anesthesiaIschemic episodesPregnant womenPrenatal careUnivariate analysisParturientsComparison of Nifedipine GITS and Hydrochlorothiazide in the Management of Elderly Patients with Stage I–III Diastolic Hypertension*
Dey H, Soufer R, Hoffer P, Wackers F, Black H. Comparison of Nifedipine GITS and Hydrochlorothiazide in the Management of Elderly Patients with Stage I–III Diastolic Hypertension*. American Journal Of Hypertension 1996, 9: 598-606. PMID: 8783785, DOI: 10.1016/0895-7061(96)00168-9.Peer-Reviewed Original ResearchConceptsNifedipine gastrointestinal therapeutic systemGastrointestinal therapeutic systemDiastolic blood pressureBlood pressureDiastolic hypertensionStage IVentricular massCardiovascular functionTreatment differencesGoal diastolic blood pressureSignificant blood pressure reductionWeek placebo washout phasePlacebo washout phaseWeek maintenance phaseBlood pressure reductionGoal blood pressureDiastolic filling rateRenal blood flowGlomerular filtration rateLeft ventricular massBlood urea nitrogenShort-term therapyAdverse side effectsSignificant adverse effectsDiuretic therapy
1993
Sex differences in cardiac adaptation to isolated systolic hypertension
Krumholz H, Larson M, Levy D. Sex differences in cardiac adaptation to isolated systolic hypertension. The American Journal Of Cardiology 1993, 72: 310-313. PMID: 8342510, DOI: 10.1016/0002-9149(93)90678-6.Peer-Reviewed Original ResearchConceptsSystolic hypertensionLV massBlood pressureLV hypertrophyApparent cardiovascular diseaseDiastolic blood pressureBody mass indexLeft ventricular massLV wall thicknessM-mode echocardiographyM-mode echocardiogramsFramingham Offspring StudyBlood glucose levelsFramingham Heart StudyAntihypertensive medicationsDiastolic hypertensionNormotensive subjectsConcentric hypertrophyLV dilationMass indexIndex examinationChamber enlargementVentricular massCardiac adaptationCardiovascular disease
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