2022
The Impact of Reducing Nicotine Content on Adolescent Cigarette Smoking and Nicotine Exposure: Results From a Randomized Controlled Trial
Cassidy R, Tidey J, Jackson K, Cioe P, Murphy S, Krishnan-Sarin S, Hatsukami D, Colby S. The Impact of Reducing Nicotine Content on Adolescent Cigarette Smoking and Nicotine Exposure: Results From a Randomized Controlled Trial. Nicotine & Tobacco Research 2022, 25: 918-927. PMID: 36482794, PMCID: PMC10077938, DOI: 10.1093/ntr/ntac279.Peer-Reviewed Original ResearchConceptsVLNC cigarettesAdolescent daily smokersNNC cigarettesCigarette smokingDaily smokersWeek 3First clinical trialSources of nicotineNicotine contentLow nicotine contentAdolescent cigarette smokingRespiratory symptomsSecondary outcomesPrimary outcomeControlled TrialsNicotine exposureTotal cigarettesIncomplete adherenceNicotine cigarettesClinical trialsAdolescent smokersTwo-armUS FoodControl groupDrug Administration
2017
Impulsivity and Approach Tendencies Towards Cigarette Stimuli: Implications for Cigarette Smoking and Cessation Behaviors Among Youth
Weckler H, Kong G, Larsen H, Cousijn J, Wiers RW, Krishnan-Sarin S. Impulsivity and Approach Tendencies Towards Cigarette Stimuli: Implications for Cigarette Smoking and Cessation Behaviors Among Youth. Experimental And Clinical Psychopharmacology 2017, 25: 363-372. PMID: 29048185, PMCID: PMC6849389, DOI: 10.1037/pha0000139.Peer-Reviewed Original ResearchConceptsCognitive bias modificationBarratt Impulsiveness ScaleExperiential Discounting TaskApproach tendenciesAdolescent smokersApproach bias modificationEffect of impulsivityConstruct of impulsivityAdolescent smoking statusHigher BIS scoresBias modificationCigarette stimuliSmoking statusHigh impulsivityImpulsiveness ScaleImpulsivitySham trainingStudy 1Study 2Adolescents' oddsSmoking cessation interventionCessation outcomesBIS scoresTreatment studiesSmoking behaviorAn Open-Label Pilot Study of an Intervention Using Mobile Phones to Deliver Contingency Management of Tobacco Abstinence to High School Students
Kong G, Goldberg AL, Dallery J, Krishnan-Sarin S. An Open-Label Pilot Study of an Intervention Using Mobile Phones to Deliver Contingency Management of Tobacco Abstinence to High School Students. Experimental And Clinical Psychopharmacology 2017, 25: 333-337. PMID: 29048181, PMCID: PMC5687821, DOI: 10.1037/pha0000151.Peer-Reviewed Original ResearchConceptsAdolescent smokersEnd of treatmentPerson cognitive-behavioural therapyCognitive behavioral therapyDaily adolescent smokersCarbon monoxide samplesSeven-day point prevalence abstinencePoint prevalence abstinenceValid videosSmoking cessation interventionParticipants' perceptionsTobacco abstinenceText messagesPilot studyPreliminary efficacyDaily text messagesMonetary incentivesCessation interventionsRemote deliveryAbstinenceParticipantsStudy findingsSaliva samplesSmokersInterventionReward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation
Garrison KA, Yip SW, Balodis IM, Carroll KM, Potenza MN, Krishnan-Sarin S. Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation. Drug And Alcohol Dependence 2017, 177: 268-276. PMID: 28651213, PMCID: PMC5564393, DOI: 10.1016/j.drugalcdep.2017.03.035.Peer-Reviewed Original ResearchConceptsAdolescent smokersReward anticipationNeural responsesMonetary incentive delay taskBehavioral Activation ScaleIncentive delay taskNeural reward systemVentral striatal activationCessation treatmentMedial prefrontal cortexBilateral nucleus accumbensNeural correlatesSmoking cessation treatmentActivation ScalesBehavioral inhibitionFrontostriatal responseDelay taskFrontostriatal activityAdolescent nonsmokersStriatal activationPrefrontal cortexEffective smoking cessation interventionsReward systemSmoking cessation interventionTobacco use disorderIntra-individual changes in Stroop-related neural activations linked to cigarette abstinence in adolescent smokers
Yip S, Krishnan-Sarin S, Balodis I, Carroll K, Potenza M. Intra-individual changes in Stroop-related neural activations linked to cigarette abstinence in adolescent smokers. Drug And Alcohol Dependence 2017, 171: e221. DOI: 10.1016/j.drugalcdep.2016.08.603.Peer-Reviewed Original Research
2016
Assessment of pain in adolescents: Influence of gender, smoking status and tobacco abstinence
Bagot KS, Wu R, Cavallo D, Krishnan-Sarin S. Assessment of pain in adolescents: Influence of gender, smoking status and tobacco abstinence. Addictive Behaviors 2016, 67: 79-85. PMID: 28061378, PMCID: PMC5965278, DOI: 10.1016/j.addbeh.2016.12.010.Peer-Reviewed Original ResearchConceptsLower pain toleranceMale smokersFemale nonsmokersPain thresholdFemale smokersPain toleranceCold pressor taskMinimal deprivationAcute smoking abstinenceLower pain thresholdPain-related factorsHigher pain intensityAssessment of painEffect of painPain 15Pain intensitySmoking statusMale nonsmokersPain responseSmoking deprivationSubjective painSmoking abstinenceTobacco abstinenceAdolescent smokersNonsmokers
2015
Predicting Initiation of Smoking Cessation Treatment and Outcome among Adolescents Using Stressful Life Events and Coping Style
Schepis TS, Cavallo DA, Kong G, Liss T, Liss A, Krishnan-Sarin S. Predicting Initiation of Smoking Cessation Treatment and Outcome among Adolescents Using Stressful Life Events and Coping Style. Substance Abuse 2015, 36: 478-485. PMID: 25424569, PMCID: PMC5507612, DOI: 10.1080/08897077.2014.983585.Peer-Reviewed Original ResearchConceptsSelf-control resourcesLife event stressorsBehavioral copingLife eventsAbstinence statusHelpless copingCessation treatmentContingency managementStressful life eventsSupport copingAvoidant copingCBT treatmentBehavior useCoping stylesTotal life eventsAdolescent smokersTreatment abstinenceAdolescent smokingCopingPsychosocial characteristicsCessation outcomesGreater useQuit attemptsTreatment initiationAbstinenceRe-training automatic action tendencies to approach cigarettes among adolescent smokers: a pilot study
Kong G, Larsen H, Cavallo DA, Becker D, Cousijn J, Salemink E, D’Escury-Koenigs A, Morean ME, Wiers RW, Krishnan-Sarin S. Re-training automatic action tendencies to approach cigarettes among adolescent smokers: a pilot study. The American Journal Of Drug And Alcohol Abuse 2015, 41: 425-432. PMID: 26186485, PMCID: PMC4561007, DOI: 10.3109/00952990.2015.1049492.Peer-Reviewed Original ResearchConceptsCognitive bias modificationCognitive behavioral therapyApproach biasesAdolescent smokersAction tendenciesAutomatic action tendenciesSeven-day point prevalence abstinenceSmoking cessation outcomesApproach biasBias modificationAvoidance biasesSmoking stimuliComputerized tasksBehavioral therapyPoint prevalence abstinenceTreatment conditionsSham trainingSham conditionCessation outcomesFuture researchBiasesCBM approachPilot studyLarge sampleAdolescents
2014
Contingency management improves smoking cessation treatment outcomes among highly impulsive adolescent smokers relative to cognitive behavioral therapy
Morean ME, Kong G, Camenga DR, Cavallo DA, Carroll KM, Pittman B, Krishnan-Sarin S. Contingency management improves smoking cessation treatment outcomes among highly impulsive adolescent smokers relative to cognitive behavioral therapy. Addictive Behaviors 2014, 42: 86-90. PMID: 25462659, PMCID: PMC4285343, DOI: 10.1016/j.addbeh.2014.11.009.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyImpulsive adolescentsAdolescent smokersContingency managementBehavioral therapyPoint prevalence abstinenceSelf-reported abstinenceEfficacy of CBTInteraction of impulsivitySelf-reported impulsivityBarratt Impulsiveness ScalePercent days abstinentSelf-reported abstinence ratesCessation treatment outcomeSmoking cessation trialImpulsiveness ScaleDays abstinentSignificant deficitsLinear modelingAdolescentsEOT abstinenceTreatment outcomesImpulsivityTeen smokersCessation trialMarijuana and Alcohol Use and Attempted Smoking Cessation in Adolescent Boys and Girls
Camenga DR, Kong G, Bagot K, Hoff RA, Potenza MN, Krishnan-Sarin S. Marijuana and Alcohol Use and Attempted Smoking Cessation in Adolescent Boys and Girls. Substance Abuse 2014, 35: 381-386. PMID: 25174418, PMCID: PMC4268029, DOI: 10.1080/08897077.2014.958207.Peer-Reviewed Original ResearchConceptsCigarette quit attemptsFrequent binge drinkingQuit attemptsAlcohol useAdolescent smokersBinge drinkingMarijuana useCurrent cigarette smokersFemale adolescent smokersGender-related associationCross-sectional surveyLogistic regression modelsSmoking cessationCigarette smokersSignificant gender interactionDecreased oddsHealth behaviorsGreater substance usePast monthSmokersSubstance useImplicit Motivational Processes Underlying Smoking in American and Dutch Adolescents
Larsen H, Kong G, Becker D, Cousijn J, Boendermaker W, Cavallo D, Krishnan-Sarin S, Wiers R. Implicit Motivational Processes Underlying Smoking in American and Dutch Adolescents. Frontiers In Psychiatry 2014, 5: 51. PMID: 24904435, PMCID: PMC4032927, DOI: 10.3389/fpsyt.2014.00051.Peer-Reviewed Original ResearchCognitive biasesDutch adolescentsAttentional biasInhibition skillsAmerican adolescentsNicotine dependenceBalloon Analogue Risk TaskApproach-avoidance biasEmotional Stroop taskStronger attentional biasImplicit Association TaskApproach-avoidance taskDrug-related stimuliGroup of smokersAvoidance biasGreater nicotine dependenceStroop taskMotivational processesNeutral stimuliRelative predictive valueAssociation taskNon-smoking adolescentsRisk TaskAdolescent smokersDaily cigarette use
2013
An exploratory randomized controlled trial of a novel high-school-based smoking cessation intervention for adolescent smokers using abstinence–contingent incentives and cognitive behavioral therapy
Krishnan-Sarin S, Cavallo DA, Cooney JL, Schepis TS, Kong G, Liss TB, Liss AK, McMahon TJ, Nich C, Babuscio T, Rounsaville BJ, Carroll KM. An exploratory randomized controlled trial of a novel high-school-based smoking cessation intervention for adolescent smokers using abstinence–contingent incentives and cognitive behavioral therapy. Drug And Alcohol Dependence 2013, 132: 346-351. PMID: 23523130, PMCID: PMC3748248, DOI: 10.1016/j.drugalcdep.2013.03.002.Peer-Reviewed Original ResearchConceptsSmoking cessation interventionCognitive behavioral therapyAbstinence-contingent incentivesAdolescent smokersCessation interventionsBehavioral therapyCigarette useEffective smoking cessation interventionsUrine cotinine levelsPoint prevalence abstinenceShort-term abstinenceSecondary outcomesCotinine levelsPrimary outcomeCessation treatmentCessation barriersCessation skillsFirst cigaretteFollow-upSmokersHigher abstinenceSurvival analysisNovel interventionsFour weeksHigh schoolChapter 35 Medications to Treat Addictions Nicotine Replacement
Herman A, Sofuoglu M. Chapter 35 Medications to Treat Addictions Nicotine Replacement. 2013, 337-343. DOI: 10.1016/b978-0-12-398338-1.00035-x.Peer-Reviewed Original ResearchNicotine replacement therapyTobacco addictionMajor public health problemNicotine deliveryPublic health problemMore effective treatmentsPatient-treatment matchingNRT formulationsPostpartum smokersNicotine replacementEffective medicationsReplacement therapySmoking cessationTobacco usageAdolescent smokersClinical guidanceEffective treatmentSmokersHealth problemsTreatment matchingMedicationsPromising findingsSmokingAddictionGreat need
2012
A preliminary experimental investigation of peer influence on risk-taking among adolescent smokers and non-smokers
Cavalca E, Kong G, Liss T, Reynolds EK, Schepis TS, Lejuez CW, Krishnan-Sarin S. A preliminary experimental investigation of peer influence on risk-taking among adolescent smokers and non-smokers. Drug And Alcohol Dependence 2012, 129: 163-166. PMID: 23131775, PMCID: PMC3578974, DOI: 10.1016/j.drugalcdep.2012.09.020.Peer-Reviewed Original ResearchConceptsPeer influenceRisk-taking behaviorAdolescent risk-taking behaviorMeasures of impulsivityBIS-11 scoresAdolescent smokersDependent measuresCounterbalanced orderExperimental sessionsPeer componentLaboratory settingAdolescentsSignificant interactionRelationship of changesSmoking statusEpidemiological evidenceTobacco useSmokersImpulsivityMean numberMeasuresGreater increaseRelationshipTaskSimilar relationship
2011
Targeted Smoking Cessation Messages for Adolescents
Latimer AE, Krishnan-Sarin S, Cavallo DA, Duhig A, Salovey P, O'Malley SA. Targeted Smoking Cessation Messages for Adolescents. Journal Of Adolescent Health 2011, 50: 47-53. PMID: 22188833, DOI: 10.1016/j.jadohealth.2011.04.013.Peer-Reviewed Original ResearchConceptsSmoking cessation messagesCessation messagesAdolescent smokersLoss-framed informationGain-framed messagesLoss-framed messagesShort-term health consequencesMessage preferencesQuasi-experimental crossover designHealth consequencesLong-term health consequencesCopy testAdolescents' preferencesMessage framesFormative evaluationAdolescentsPositive attitudesMessage contentCrossover designMost participantsStudy findingsPresentation approachSmokersImportant implicationsVideo
2010
Preliminary Examination of Adolescent Spending in a Contingency Management-Based Smoking-Cessation Program
Cavallo DA, Nich C, Schepis TS, Smith AE, Liss TB, McFetridge AK, Krishnan-Sarin S. Preliminary Examination of Adolescent Spending in a Contingency Management-Based Smoking-Cessation Program. Journal Of Child & Adolescent Substance Abuse 2010, 19: 335-342. PMID: 20802850, PMCID: PMC2928574, DOI: 10.1080/1067828x.2010.502498.Peer-Reviewed Original ResearchNicotine dependence severity as a cross-sectional predictor of alcohol-related problems in a sample of adolescent smokers
Leeman RF, Schepis TS, Cavallo DA, McFetridge AK, Liss TB, Krishnan-Sarin S. Nicotine dependence severity as a cross-sectional predictor of alcohol-related problems in a sample of adolescent smokers. Nicotine & Tobacco Research 2010, 12: 521-524. PMID: 20231243, PMCID: PMC2861884, DOI: 10.1093/ntr/ntq024.Peer-Reviewed Original ResearchConceptsAlcohol-related problemsCross-sectional predictorsAdolescent smokersNicotine dependence severityND severityDependence severityClinical trialsHierarchical multiple regressionSmoking cessation clinical trialSmoking-related variablesFagerström Tolerance QuestionnaireCessation clinical trialKey demographicsAlcohol involvementCigarette smokingClinical indicatorsAlcohol useNegative consequencesTolerance QuestionnaireAlcohol consumptionAdolescentsSmokersMultiple regressionSeverityCross-sectional model
2008
Contingency management for smoking cessation: enhancing feasibility through use of immunoassay test strips measuring cotinine.
Schepis TS, Duhig AM, Liss T, McFetridge A, Wu R, Cavallo DA, Dahl T, Jatlow P, Krishnan-Sarin S. Contingency management for smoking cessation: enhancing feasibility through use of immunoassay test strips measuring cotinine. Nicotine & Tobacco Research 2008, 10: 1495-501. PMID: 19023841, PMCID: PMC3679884, DOI: 10.1080/14622200802323209.Peer-Reviewed Original ResearchConceptsContingency managementAdolescent smokersTreatment-seeking adultsQuit attemptsSmoking cessationUse of cotinineUrinary cotinineBehavioral interventionsIntervention programsImmunoassay test stripUrinary cotinine levelsAbstinenceMultiple daily measurementsObjective indicatorsDaily appointmentsCotinine levelsCotinineImmunoassay testingGood markerAdultsBreath COVariety of substancesInterventionCessationSmokersPreliminary Examination of Tobacco Withdrawal in Adolescent Smokers During Smoking Cessation Treatment
Smith AE, Cavallo DA, McFetridge A, Liss T, Krishnan-Sarin S. Preliminary Examination of Tobacco Withdrawal in Adolescent Smokers During Smoking Cessation Treatment. Nicotine & Tobacco Research 2008, 10: 1253-1259. PMID: 18629736, PMCID: PMC3777831, DOI: 10.1080/14622200802219357.Peer-Reviewed Original ResearchConceptsTobacco withdrawal symptomsWithdrawal symptomsAdolescent smokersSmoking cessation treatmentCourse of symptomsCourse of treatmentImplementation of treatmentCessation treatmentCessation interventionsProspective studyTobacco withdrawalQuit dayAdult smokersNicotine dependenceSmokersSymptomsSmokingTreatmentWeeksBoysGirlsSubsequent declineCourseExacerbationRelapseEffects of Acute Tobacco Abstinence in Adolescent Smokers Compared with Nonsmokers
Smith AE, Cavallo DA, Dahl T, Wu R, George TP, Krishnan-Sarin S. Effects of Acute Tobacco Abstinence in Adolescent Smokers Compared with Nonsmokers. Journal Of Adolescent Health 2008, 43: 46-54. PMID: 18565437, PMCID: PMC2527725, DOI: 10.1016/j.jadohealth.2007.12.004.Peer-Reviewed Original ResearchConceptsAdolescent smokersInitiation of abstinenceMood symptomsAcute tobacco abstinenceNicotine withdrawal symptomsNegative mood symptomsAbstinence-induced changesHours of abstinenceCigarette smokingNicotine withdrawalWithdrawal symptomsDaily smokingTobacco abstinenceAdult smokersTobacco useInpatient sessionsSmokersSimilar subjective effectsNonsmokersAbstinence effectsSymptomsAbstinence periodAdolescent nonsmokersMood changesProlonged abstinence
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