2025
20 Years of Aberrant Salience in Psychosis: What Have We Learned?
Corlett P, Fraser K. 20 Years of Aberrant Salience in Psychosis: What Have We Learned? American Journal Of Psychiatry 2025, appiajp20240556. PMID: 40134268, DOI: 10.1176/appi.ajp.20240556.Peer-Reviewed Original ResearchDopamine systemComputational cognitive neuroscienceAberrant salienceDelusion formationDopamine dysfunctionDopaminergic circuitsSalience hypothesisCognitive neuroscienceNeurochemical dysfunctionBehavioral neuroscientistsClinical phenomenologyCogent theoryDopaminePsychosisNovel predictionsBehavioral lociDelusionsAttention of cliniciansContemporary theoriesBelief formationHallucinationsBeliefsNeuroscienceDysfunctionNeuroscientists
2020
O3.4. PSYCHOSIS PHENOTYPES FROM B-SNIP FOR CLINICAL ADVANCES: BIOTYPE CHARACTERISTICS AND TARGETS
Clementz B, Trotti R, Pearlson G, Keshavan M, Gershon E, Keedy S, Ivleva E, McDowell J, Tamminga C. O3.4. PSYCHOSIS PHENOTYPES FROM B-SNIP FOR CLINICAL ADVANCES: BIOTYPE CHARACTERISTICS AND TARGETS. Schizophrenia Bulletin 2020, 46: s7-s7. PMCID: PMC7234003, DOI: 10.1093/schbul/sbaa028.015.Peer-Reviewed Original ResearchClinical featuresPsychosis biotypesPsychosis casesPsychosis syndromeTreatment targetsSpecific treatment targetsB-SNIPClinical manifestationsBiomarker profilesPsychosis subgroupsB-SNIP consortiumDeep phenotyping approachPathophysiological mechanismsPsychosis patientsBipolar-Schizophrenia NetworkPsychosis diagnosisBiological subtypesHealthy personsClinical practiceClinical advancesNegative symptomsClinical phenomenologySyndrome
2019
Anxious-Irritable Children: A Distinct Subtype of Childhood Anxiety?
Shimshoni Y, Lebowitz ER, Brotman MA, Pine DS, Leibenluft E, Silverman WK. Anxious-Irritable Children: A Distinct Subtype of Childhood Anxiety? Behavior Therapy 2019, 51: 211-222. PMID: 32138933, PMCID: PMC7080292, DOI: 10.1016/j.beth.2019.06.005.Peer-Reviewed Original Research
2017
Explaining Delusions: Reducing Uncertainty Through Basic and Computational Neuroscience
Feeney EJ, Groman SM, Taylor JR, Corlett PR. Explaining Delusions: Reducing Uncertainty Through Basic and Computational Neuroscience. Schizophrenia Bulletin 2017, 43: 263-272. PMID: 28177090, PMCID: PMC5605246, DOI: 10.1093/schbul/sbw194.Peer-Reviewed Original ResearchConceptsAssociative learning theoryPersistence of delusionsAttentional allocationCognitive psychologySet of beliefsAnimal beliefsNew learningComputational neuroscienceLearning theoryHuman beliefsErroneous beliefsBelief characteristicsBrain functionConsensual realityClinical phenomenologyAnimal researchBeliefsDelusionsComputational modelPsychotic illnessPsychologyPharmacological treatmentNeuroscienceTeleological approachFuture state
2015
Arm Posturing in a Patient Following Stroke: Dystonia, Levitation, Synkinesis, or Spasticity?
Irmady K, Jabbari B, Louis ED. Arm Posturing in a Patient Following Stroke: Dystonia, Levitation, Synkinesis, or Spasticity? Tremor And Other Hyperkinetic Movements 2015, 5: 353. PMID: 26682091, PMCID: PMC4681881, DOI: 10.7916/d8222tbh.Peer-Reviewed Original ResearchPost-stroke movement disordersArm contralateralArm posturingInvoluntary elevationIschemic strokeStroke patientsFollowing StrokeMovement disordersAppropriate treatmentDifferential diagnosisClinical phenomenologyDiagnostic possibilitiesSpasticitySynkinesisArm levitationDystoniaStrokeUnusual movementsPatientsContralateralDiagnosis
2013
Primary dystonias and genetic disorders with dystonia as clinical feature of the disease
Moghimi N, Jabbari B, Szekely AM. Primary dystonias and genetic disorders with dystonia as clinical feature of the disease. European Journal Of Paediatric Neurology 2013, 18: 79-105. PMID: 23911094, DOI: 10.1016/j.ejpn.2013.05.015.Peer-Reviewed Original ResearchConceptsPrimary dystoniaClinical featuresSustained muscle contractionsCharacteristic clinical featuresClinical entityAbnormal postureMovement disordersDystoniaClinical practiceClinical phenomenologyAdvances of geneticsGenetic syndromesMuscle contractionRepetitive movementsUnderlining etiologiesDisordersCommon formMonogenic disordersGenetic disordersMolecular underpinningsDetailed searchMendelian disordersComplex casesLarge groupSyndrome
2006
External validation of comorbid patterns of anxiety disorders in children and adolescents
Franco X, Saavedra LM, Silverman WK. External validation of comorbid patterns of anxiety disorders in children and adolescents. Journal Of Anxiety Disorders 2006, 21: 717-729. PMID: 17095184, PMCID: PMC2692683, DOI: 10.1016/j.janxdis.2006.10.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxiety DisordersAttention Deficit and Disruptive Behavior DisordersAttention Deficit Disorder with HyperactivityChildChild of Impaired ParentsComorbidityConduct DisorderDepressive DisorderEducational StatusFemaleHumansInternal-External ControlInterpersonal RelationsMalePeer GroupPersonality AssessmentRisk FactorsConceptsAnxiety disordersComorbid patternsDiagnostic presentationAnxiety disorder casesExternal validityClinical phenomenologyFuture research implicationsAnxiety groupComorbid groupFamily factorsDisorder groupPsychosocial factorsComorbid casesResearch implicationsPure anxiety disordersStructured interviewsAnxietyAdolescentsDisorder casesExternal validation criteriaDisordersPure anxietyChildrenValidityPhenomenology
2003
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis I. Study rationale and design
McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller TJ, Woods SW, Hawkins KA, Hoffman R, Lindborg S, Tohen M, Breier A. The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis I. Study rationale and design. Schizophrenia Research 2003, 61: 7-18. PMID: 12648731, DOI: 10.1016/s0920-9964(02)00439-5.Peer-Reviewed Original ResearchConceptsPsychosis onsetClinical trialsDouble-blind placebo-controlled clinical trialStudy rationaleDouble-blind clinical trialPlacebo-controlled clinical trialAtypical neuroleptic medicationsNew diagnostic criteriaClinical trial designPutative prodromal syndromeTreatment-seeking patientsOngoing symptomatologyNeuroleptic medicationHigh riskDiagnostic criteriaTrial designEarly courseProdromal SyndromesClinical phenomenologyStudy designClinical populationsPatientsOnsetIntervention researchTrials
1998
Trichotillomania, Obsessive-Compulsive Disorder, and Tourette Syndrome: Comorbid Relationships and Risks for Expression
O'Sullivan R, Miguel E, Coffey B, Rauch S, Savage C, Keuthen N, Baer L, Jenike M. Trichotillomania, Obsessive-Compulsive Disorder, and Tourette Syndrome: Comorbid Relationships and Risks for Expression. CNS Spectrums 1998, 3: 49-51. DOI: 10.1017/s1092852900006659.Peer-Reviewed Original ResearchObsessive-compulsive disorderTourette syndromeComorbid relationshipConsiderable psychological distressUnderdiagnosed syndromePotential treatment implicationsTic disordersDopamine antagonistsTreatment responseClinical phenomenologyPhysical disfigurementSyndromePsychological distressTreatment implicationsDisordersStructured interviews
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply