2024
Treatment-wise glioblastoma survival Inference with multi-parametric preoperative MRI
Liu X, Shusharina N, Shih H, Kuo C, El Fakhri G, Woo J. Treatment-wise glioblastoma survival Inference with multi-parametric preoperative MRI. Proceedings Of SPIE--the International Society For Optical Engineering 2024, 12927: 129272h-129272h-5. PMID: 39444513, PMCID: PMC11497473, DOI: 10.1117/12.3006897.Peer-Reviewed Original Research
2023
The clinical and genomic features of seizures in meningiomas
Dincer A, Jalal M, Gupte T, Vetsa S, Vasandani S, Yalcin K, Marianayagam N, Blondin N, Corbin Z, McGuone D, Fulbright R, Erson-Omay Z, Günel M, Moliterno J. The clinical and genomic features of seizures in meningiomas. Neuro-Oncology Advances 2023, 5: i49-i57. PMID: 37287582, PMCID: PMC10243847, DOI: 10.1093/noajnl/vdac110.Peer-Reviewed Original ResearchPeritumoral brain edemaPostoperative seizuresBrain invasionSubtotal resectionBrain edemaLarge residual tumor volumeCentral nervous system tumorsCommon central nervous system tumorPersistent postoperative seizuresResidual tumor volumeHistory of seizuresHigh tumor gradeNervous system tumorsQuality of lifePreoperative seizuresAtypical histologyMost patientsSurgical resectionCortical hyperexcitabilityUncontrolled seizuresAggressive featuresSeizure activityEpileptogenic focusCortical irritationRisk factorsClinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas.
Tabor J, O'Brien J, Vasandani S, Vetsa S, Lei H, Jalal M, Marianayagam N, Jin L, Millares Chavez M, Haynes J, Dincer A, Yalcin K, Aguilera S, Omay S, Mishra-Gorur K, McGuone D, Morales-Valero S, Fulbright R, Gunel M, Erson-Omay E, Moliterno J. Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas. Journal Of Neurosurgery 2023, 139: 1648-1656. PMID: 37243548, DOI: 10.3171/2023.4.jns222929.Peer-Reviewed Original ResearchConceptsSubtotal resectionSupratentorial tumorsElevated Ki-67High-risk featuresProgression-free survivalChromosome 1p deletionInfratentorial counterpartsInfratentorial tumorsPostoperative managementSomatic driver mutationsCerebral convexityGrade IIInfratentorial meningiomasKi-67Posterior fossaLoss of heterozygosityMeningiomasResectionTumorsWhole-exome sequencing dataDriver mutationsHigh gradeSignificant differencesExome sequencing dataSporadic meningiomas
2020
Thalamic tumors in children: case series from our institution and literature review
Renedo D, Ferraro F, Johnson A, Argañaraz R, Giovannini S, Zabala J, Zemma E, Mantese B. Thalamic tumors in children: case series from our institution and literature review. Child's Nervous System 2020, 37: 457-463. PMID: 32712861, DOI: 10.1007/s00381-020-04830-0.Peer-Reviewed Original ResearchConceptsThalamic tumorsCase seriesSurgical approachStereotactic-guided biopsyGross total resectionEndoscopic third ventriculostomyGrade IV tumorsHigh-grade tumorsInvasive surgical proceduresTime of treatmentSubtotal resectionMedian ageVentriculoperitoneal shuntMotor deficitsGrade IIIThird ventriculostomyGrade IGrade IIObservational studySurgical proceduresPatientsResultsFrom 2013TumorsCommon formResection
2019
Extent of resection of epidermoid tumors and risk of recurrence: case report and meta-analysis.
Shear BM, Jin L, Zhang Y, David WB, Fomchenko EI, Erson-Omay EZ, Huttner A, Fulbright RK, Moliterno J. Extent of resection of epidermoid tumors and risk of recurrence: case report and meta-analysis. Journal Of Neurosurgery 2019, 133: 291-301. PMID: 31277071, DOI: 10.3171/2019.4.jns19598.Peer-Reviewed Original ResearchGross total resectionSubtotal resectionRecurrence rateAverage recurrence rateEpidermoid tumorsSafe gross total resectionTransient cranial nerve palsyUnderwent subtotal resectionCranial nerve palsyCommon surgical complicationExtent of resectionRisk of recurrenceTreatment of choiceCritical neurovascular structuresLong-term riskUse of adjunctsIntracranial epidermoid tumorsCubic spline modelsWeb of ScienceNerve palsyRepeat resectionInitial surgeryNatural cubic spline modelSurgical complicationsPooled proportion
2018
P04.60 Genomic profile of tumorigenesis in a patient with Turcot syndrome
Karschnia P, Erson-Omay E, Huttner A, Fulbright R, Günel M, Baehring J. P04.60 Genomic profile of tumorigenesis in a patient with Turcot syndrome. Neuro-Oncology 2018, 20: iii293-iii293. PMCID: PMC6143975, DOI: 10.1093/neuonc/noy139.294.Peer-Reviewed Original ResearchWhole-exome sequencingEndometrial carcinomaTurcot syndromeBrain tumorsMicrosatellite instabilityMMR genesSecond hitSomatic missense mutationsMissense mutationsLeft frontal tumorPrimary brain tumorsPatient's brain tumorMismatch repair deficiencyMMR-deficient tumorsExpression of MSH6Heterozygous germline mutationsHeterozygous germline missense mutationRight hemiparesisSubtotal resectionUterine adenocarcinomaMetachronous tumorsFrontal tumorGermline missense mutationAbdominal tumorsFamily history
2017
Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas?
Omay SB, Almeida JP, Chen YN, Shetty SR, Liang B, Ni S, Anand VK, Schwartz TH. Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas? Journal Of Neurosurgery 2017, 129: 642-647. PMID: 29171802, DOI: 10.3171/2017.6.jns163188.Peer-Reviewed Original ResearchConceptsGross total resectionExtended endonasal approachSubtotal resectionLarge tumorsPituitary glandFirst-line surgical approachEndonasal endoscopic resectionAvailable preoperative imagingMidline craniopharyngiomasOBJECTIVE CraniopharyngiomasPrefixed chiasmEndocrine outcomesRelative contraindicationVisual outcomeEndoscopic resectionAuthors' centerPreoperative imagingOptic chiasmSurgical approachVisual deteriorationResults ThirtyPituitary stalkThird ventricleHigh riskResection
2016
Primary spinal myxopapillary ependymoma in the pediatric population: a study from the Surveillance, Epidemiology, and End Results (SEER) database
Lucchesi KM, Grant R, Kahle KT, Marks AM, DiLuna ML. Primary spinal myxopapillary ependymoma in the pediatric population: a study from the Surveillance, Epidemiology, and End Results (SEER) database. Journal Of Neuro-Oncology 2016, 130: 133-140. PMID: 27423644, DOI: 10.1007/s11060-016-2218-6.Peer-Reviewed Original ResearchConceptsGross total resectionOverall survivalSpinal myxopapillary ependymomaMyxopapillary ependymomaSubtotal resectionPatient demographicsPediatric patientsEnd Results (SEER) databaseNational Cancer DatabaseKaplan-Meier methodGoal of treatmentYears of ageLargest survival analysisAdjuvant radiationMean followPatients 21SEER databaseSurgical resectionMedian agePediatric populationResults databaseTumor recurrenceCauda equinaTreatment modalitiesCancer Database
2014
Clinical course and progression-free survival of adult intracranial and spinal ependymoma patients
Vera-Bolanos E, Aldape K, Yuan Y, Wu J, Wani K, Necesito-Reyes MJ, Colman H, Dhall G, Lieberman FS, Metellus P, Mikkelsen T, Omuro A, Partap S, Prados M, Robins HI, Soffietti R, Wu J, Gilbert MR, Armstrong TS. Clinical course and progression-free survival of adult intracranial and spinal ependymoma patients. Neuro-Oncology 2014, 17: 440-447. PMID: 25121770, PMCID: PMC4483095, DOI: 10.1093/neuonc/nou162.Peer-Reviewed Original ResearchConceptsProgression-free survivalClinical courseEpendymoma patientsMultivariate Cox proportional hazards modelMultivariate Cox proportional hazardsCox proportional hazards modelRare CNS tumorsTime of diagnosisPrognostic clinical factorsCox proportional hazardsProportional hazards modelSubtotal resectionClinical factorsMedian timeCNS tumorsCentral reviewGrade IIIMean ageTumor recurrenceEarly progressionTumor locationGrade IITumor gradeUnivariate analysisSupratentorial location
2012
Pegylated interferon-α-2b for children with recurrent craniopharyngioma.
Yeung JT, Pollack IF, Panigrahy A, Jakacki RI. Pegylated interferon-α-2b for children with recurrent craniopharyngioma. Journal Of Neurosurgery Pediatrics 2012, 10: 498-503. PMID: 23061825, DOI: 10.3171/2012.9.peds12225.Peer-Reviewed Original ResearchConceptsMonths of treatmentGross total resectionPatient experienced recurrenceRecurrent craniopharyngiomaExperienced recurrenceSubtotal resectionComplete responseRadiation therapyUse of PIDisease 19 monthsDisease 6 monthsDisease 10 yearsInterferon α-2bStable diseaseDurable responsesIntralesional administrationCystic tumorTumor sizeTumor responseSubcutaneous injectionCystic componentFurther interventionCraniopharyngiomaRecurrenceSustained exposure
2009
Seizures in Patients Undergoing Resection of Low-Grade Gliomas
Hirsch LJ. Seizures in Patients Undergoing Resection of Low-Grade Gliomas. Epilepsy Currents 2009, 9: 98-100. PMID: 19693324, PMCID: PMC2728484, DOI: 10.1111/j.1535-7511.2009.01305.x.Peer-Reviewed Original ResearchLow-grade gliomasPostoperative seizure controlGross total resectionSeizure controlSeizure characteristicsLong seizure historyPatients Undergoing ResectionRetrospective chart reviewCohort of patientsMajority of patientsPoor seizure controlTreatment-related variablesSimple partial seizuresUndergoing resectionInitial surgeryPharmacoresistant seizuresSeizure improvementSeizure recurrenceAdult patientsChart reviewRare seizuresSubtotal resectionSurgical resectionFavorable prognosisPartial seizures
2005
The growing teratoma syndrome after subtotal resection of an intracranial nongerminomatous germ cell tumor in an adult: case report.
Bi W, Bannykh S, Baehring J. The growing teratoma syndrome after subtotal resection of an intracranial nongerminomatous germ cell tumor in an adult: case report. Neurosurgery 2005, 56: 188. PMID: 15617603.Peer-Reviewed Original ResearchConceptsNongerminomatous germ cell tumorsGerm cell tumorsIntracranial nongerminomatous germ cell tumorsTeratoma syndromeCell tumorsMature teratomaTumor serum markersGerm cell neoplasmsTotal tumor resectionTreatment of choiceYolk sac tumorEndoscopic third ventriculostomyMultilocular cystic massLarge multilocular cystic massMultimodality therapyMultimodality treatmentPartial responseSubtotal resectionSurgical resectionAdult patientsRare complicationSerum markersCystic massSac tumorCase report
1985
New applications of total parathyroidectomy and autotransplantation: Use in proximal renal tubular dysfunction
Kinder B, Rasmussen H. New applications of total parathyroidectomy and autotransplantation: Use in proximal renal tubular dysfunction. World Journal Of Surgery 1985, 9: 156-164. PMID: 3838609, DOI: 10.1007/bf01656271.Peer-Reviewed Original ResearchConceptsTotal parathyroidectomyMetabolic bone diseaseBone diseaseProximal renal tubular dysfunctionGraft-dependent hypercalcemiaSevere bone diseaseVitamin D intoxicationTreatment of hyperparathyroidismCases of recurrentRenal tubular dysfunctionNew clinical settingsParathyroid massPersistent hyperparathyroidismRecurrent diseaseSecondary hyperparathyroidismPolyendocrine syndromeRenal osteodystrophySubtotal resectionFurther recurrenceParathyroid hyperplasiaTubular dysfunctionLocal anesthesiaEffective treatmentGraft tissueHigh incidence
1984
Adenocarcinoma in Barrett's esophagus after elimination of gastroesophageal reflux
Hamilton S, Hutcheon D, Ravich W, Cameron J, Paulson M. Adenocarcinoma in Barrett's esophagus after elimination of gastroesophageal reflux. Gastroenterology 1984, 86: 356-360. PMID: 6690363, DOI: 10.1016/0016-5085(84)90423-2.Peer-Reviewed Original ResearchConceptsBarrett's esophagusGastroesophageal refluxColonic interpositionBarrett's mucosaAbsence of refluxSevere reflux esophagitisDevelopment of adenocarcinomaLong-term surveillanceLower esophageal strictureAntireflux therapyReflux esophagitisSubtotal resectionEsophageal strictureRadiographic findingsInterposition proceduresEsophagusAdenocarcinomaMucosaRefluxPatientsInterpositionProbe recordingsEsophagectomyEsophagitisResection
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply