2024
Along Came the DSM—Melancholic Depression, the Dexamethasone Suppression Test, and How Psychiatry Lost the Brain
Eloge J, Cooper J, Ross D. Along Came the DSM—Melancholic Depression, the Dexamethasone Suppression Test, and How Psychiatry Lost the Brain. Biological Psychiatry 2024, 97: 9-11. PMID: 39613386, DOI: 10.1016/j.biopsych.2024.10.014.Peer-Reviewed Original Research
2023
FRI184 Impact Of Adrenalectomy On Cognition In Patients With Mild Autonomous Cortisol Secretion
Saini J, Nathani R, Zhang C, Suresh M, Thangamuthu K, Singh S, Fell V, Atkinson E, Achenbach S, Stricker N, Bancos I. FRI184 Impact Of Adrenalectomy On Cognition In Patients With Mild Autonomous Cortisol Secretion. Journal Of The Endocrine Society 2023, 7: bvad114.179. PMCID: PMC10555084, DOI: 10.1210/jendso/bvad114.179.Peer-Reviewed Original ResearchComposite T-scoreDexamethasone suppression testImpact of adrenalectomyCognitive functionNational Institutes of Health (NIH) Toolbox Cognition BatteryCognitive evaluationT-scoreCortisol secretionLongitudinal study of adultsPost-DST cortisolProspective longitudinal study of adultsAutonomous cortisol secretionFluid cognitionCognitive batteryCrystallized cognitionImpaired cognitionTotal cognitionAssociated with improvementsCognitionStudy of adultsSuppression testAdrenal adenomaFollow-upScore changesMild autonomous cortisol secretion
2020
Spontaneous Resolution of Primary Hypercortisolism of Cushing Disease After Pituitary Hemorrhage
Siwakoti K, Omay SB, Inzucchi SE. Spontaneous Resolution of Primary Hypercortisolism of Cushing Disease After Pituitary Hemorrhage. AACE Clinical Case Reports 2020, 6: e23-e29. PMID: 32984518, PMCID: PMC7279773, DOI: 10.4158/accr-2019-0292.Peer-Reviewed Original ResearchPituitary apoplexySpontaneous resolutionBiochemical remissionPrimary hypercortisolismSellar massLow-dose dexamethasone suppression testDose dexamethasone suppression testMagnetic resonance imaging (MRI) scansUrine free cortisolSymptoms of hypercortisolismDexamethasone suppression testResonance imaging scansSymptomatic hemorrhageSurgical resectionCushing's diseaseInitial presentationPituitary hemorrhageFree cortisolFunctional adenomasImaging scansElevated plasmaSerum cortisolSuppression testClinical signsPathologic information
2009
Plasma Glucose and Insulin Regulation Is Abnormal Following Gastric Bypass Surgery with or Without Neuroglycopenia
Kim SH, Liu TC, Abbasi F, Lamendola C, Morton JM, Reaven GM, McLaughlin TL. Plasma Glucose and Insulin Regulation Is Abnormal Following Gastric Bypass Surgery with or Without Neuroglycopenia. Obesity Surgery 2009, 19: 1550. PMID: 19557485, DOI: 10.1007/s11695-009-9893-8.Peer-Reviewed Original ResearchConceptsGastric bypass surgeryInsulin sensitivityOral glucoseInsulin concentrationsPost-RYGBBypass surgeryPlasma glucoseInsulin responseControl groupOverweight/obese controlsInsulin suppression testOral glucose challengePeak insulin concentrationsNon-surgical controlsNadir glucose concentrationsAsymptomatic patientsSymptomatic hypoglycemiaObese controlsRYGB groupGlucose challengeSuppression testPeak glucosePatientsRYGBGlucose concentration
1993
Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder
Yehuda R, Southwick SM, Krystal JH, Bremner D, Charney DS, Mason JW. Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder. American Journal Of Psychiatry 1993, 150: 83-86. PMID: 8417586, DOI: 10.1176/ajp.150.1.83.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderDexamethasone administrationDexamethasone levelsLow-dose dexamethasone suppression testEnhanced negative feedback sensitivityStress disorderBaseline blood samplesDexamethasone suppression testNegative feedback sensitivityMale patientsHPA abnormalitiesSuppression testMajor depressionBlood samplesLow doseDiagnostic criteriaNormal subjectsPTSD patientsPatientsDexamethasoneCortisolGreater suppressionFeedback sensitivityEnhanced suppressionAdministration
1990
Value of the DST for predicting response of patients with major depression to hospitalization and desipramine
Nelson JC, Mazure CM, Jatlow PI. Value of the DST for predicting response of patients with major depression to hospitalization and desipramine. American Journal Of Psychiatry 1990, 147: 1488-1492. PMID: 2221161, DOI: 10.1176/ajp.147.11.1488.Peer-Reviewed Original ResearchConceptsDexamethasone suppression testResponse of patientsMajor depressionNegative dexamethasone suppression testPositive dexamethasone suppression testWeeks of hospitalizationNonpsychotic major depressionPlasma levelsSuppression testRate of responseAntidepressant drugsDrug treatmentPatientsHospitalizationDesipraminePrior reportsDepressionResponsePrior studiesPlaceboFindingsTrialsWeeks
1984
Evidence for Disordered Control of 1,25-Dihydroxyvitamin D Production in Absorptive Hypercalciuria
Broadus A, Insogna K, Lang R, Ellison A, Dreyer B. Evidence for Disordered Control of 1,25-Dihydroxyvitamin D Production in Absorptive Hypercalciuria. New England Journal Of Medicine 1984, 311: 73-80. PMID: 6330548, DOI: 10.1056/nejm198407123110201.Peer-Reviewed Original ResearchConceptsAbsorptive hypercalciuriaCalcium intakeDietary calcium intakeDihydroxyvitamin D productionRenal phosphate handlingDihydroxyvitamin DPhosphate handlingSuppression testHypercalciuriaPatientsD productionShort-term increaseSyndromeIntakePresent studyInitial levelLarge majorityPrevious studiesEvidenceAbnormalitiesWeeks
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