2011
Dorsal Striatal D2-Like Receptor Availability Covaries with Sensitivity to Positive Reinforcement during Discrimination Learning
Groman SM, Lee B, London ED, Mandelkern MA, James AS, Feiler K, Rivera R, Dahlbom M, Sossi V, Vandervoort E, Jentsch JD. Dorsal Striatal D2-Like Receptor Availability Covaries with Sensitivity to Positive Reinforcement during Discrimination Learning. Journal Of Neuroscience 2011, 31: 7291-7299. PMID: 21593313, PMCID: PMC3114883, DOI: 10.1523/jneurosci.0363-11.2011.Peer-Reviewed Original ResearchConceptsLike receptor availabilityIndividual differencesDiscrimination learningBehavioral flexibilitySpecific neurocognitive mechanismsVisual discrimination problemsBehavioral sensitivityReceptor availabilityNeurocognitive mechanismsReward sensitivityBehavioral performanceNeural mechanismsVisual discriminationNeuropsychiatric disordersPositive reinforcementReversal phaseEnvironmental contingenciesThree-choiceNumber of trialsPhenotypic dimensionsPsychiatric conditionsFeedback sensitivityLearningElectrophysiological findingsDisorders
1993
Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder
Yehuda R, Southwick SM, Krystal JH, Bremner D, Charney DS, Mason JW. Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder. American Journal Of Psychiatry 1993, 150: 83-86. PMID: 8417586, DOI: 10.1176/ajp.150.1.83.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderDexamethasone administrationDexamethasone levelsLow-dose dexamethasone suppression testEnhanced negative feedback sensitivityStress disorderBaseline blood samplesDexamethasone suppression testNegative feedback sensitivityMale patientsHPA abnormalitiesSuppression testMajor depressionBlood samplesLow doseDiagnostic criteriaNormal subjectsPTSD patientsPatientsDexamethasoneCortisolGreater suppressionFeedback sensitivityEnhanced suppressionAdministration
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