2020
Spontaneous Resolution of Primary Hypercortisolism of Cushing Disease After Pituitary Hemorrhage
Siwakoti K, Omay SB, Inzucchi SE. Spontaneous Resolution of Primary Hypercortisolism of Cushing Disease After Pituitary Hemorrhage. AACE Clinical Case Reports 2020, 6: e23-e29. PMID: 32984518, PMCID: PMC7279773, DOI: 10.4158/accr-2019-0292.Peer-Reviewed Original ResearchPituitary apoplexySpontaneous resolutionBiochemical remissionPrimary hypercortisolismSellar massLow-dose dexamethasone suppression testDose dexamethasone suppression testMagnetic resonance imaging (MRI) scansUrine free cortisolSymptoms of hypercortisolismDexamethasone suppression testResonance imaging scansSymptomatic hemorrhageSurgical resectionCushing's diseaseInitial presentationPituitary hemorrhageFree cortisolFunctional adenomasImaging scansElevated plasmaSerum cortisolSuppression testClinical signsPathologic information
2019
Higher urinary cortisol levels associate with increased cardiovascular risk
Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH. Higher urinary cortisol levels associate with increased cardiovascular risk. Endocrine Connections 2019, 8: 634-640. PMID: 31018177, PMCID: PMC6528405, DOI: 10.1530/ec-19-0182.Peer-Reviewed Original ResearchFramingham risk scoreCardiovascular riskRisk allele carriersRisk scoreAllele carriersCortisol groupCortisol levelsHigher urinary cortisol levelsUrine free cortisolNon-risk allele carriersNon-diabetic individualsBlood pressure measurementsCross-sectional studyRisk allele statusUrinary cortisol levelsIndependent predictorsUrinary cortisolBlood samplesDiscordant findingsLarger sample sizeMultivariate analysisAllele statusCortisol collectionRisk allelesSample size
2012
ACTH‐secreting pituitary microadenomas are associated with a higher prevalence of central hypothyroidism compared to other microadenoma types
Mathioudakis N, Thapa S, Wand G, Salvatori R. ACTH‐secreting pituitary microadenomas are associated with a higher prevalence of central hypothyroidism compared to other microadenoma types. Clinical Endocrinology 2012, 77: 871-876. PMID: 22587880, PMCID: PMC6031125, DOI: 10.1111/j.1365-2265.2012.04442.x.Peer-Reviewed Original ResearchConceptsUrinary free cortisolDegree of hypercortisolismCentral hypothyroidismFree T4Salivary cortisolFree cortisolMean urinary free cortisolGlucocorticoid-induced suppressionUrine free cortisolThyroid hormone replacementPituitary microTranssphenoidal adenomectomyHormone replacementACTH adenomasTSH levelsRetrospective studyPituitary macroadenomaPituitary microadenomaPituitary surgeryThyroid functionHigh prevalenceACTH-secretingHypothyroidismThyroid axisClinical practice
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