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Matthew Vesely, MD, PhD

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About

Titles

Assistant Professor of Dermatology

Biography

I am a physician-scientist who has trained in immunology, molecular biology, genetics and clinical dermatology. My overall career goal as a physician-scientist are to integrate fundamental immunology with clinical dermatology. In particular, I am interested in the role of costimulatory and inhibitory immune receptors in cancer immunity, autoimmunity pathogenesis and immunotherapy. My interest in this field was driven by my experience in the Medical Scientist Training Program at Washington University in St. Louis, where I worked in the laboratory of Dr. Robert Schreiber to decipher key molecular regulators of cancer immunoediting. As a consequence, the expertise gained in skin immunology and the emerging immunotherapies to treat melanoma inspired me to become a dermatologist. During my dermatology residency, I joined the laboratory of Dr. Lieping Chen at Yale School of Medicine, who pioneered targeting the PD-1 axis for cancer immunotherapy and has discovered multiple novel immune checkpoint molecules including programmed death receptor-1 homolog (PD-1H) (also known as VISTA). My current research interests include: 1) identification of novel immune checkpoints such as PD-1H/VISTA and others in cutaneous malignancies (e.g., melanoma and keratinocyte carcinomas) and 2) elucidating the inhibitory immune landscape of chronic inflammatory disorders such as psoriasis and cutaneous lupus erythematosus.

Appointments

Other Departments & Organizations

Education & Training

Resident
Yale School of Medicine (Dermatology) (2014-2017) (2017)
Intern
Barnes Jewish Hospital (St. Louis) (2013-2014) (2014)
PhD
Washington University School of Medicine, St. Louis, Immunology (2013)
MD
Washington University School of Medicine (2013)
BS
Creighton University, Biology, Theology, History (2003)

Research

Overview

Medical Subject Headings (MeSH)

Carcinoma, Squamous Cell; Dermatitis; Dermatitis, Atopic; Eczema; Immunoassay; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Discoid; Melanoma; Molecular Imaging; Psoriasis; Skin; Skin and Connective Tissue Diseases

Research at a Glance

Publications Timeline

A big-picture view of Matthew Vesely's research output by year.

Publications

Featured Publications

Clinical Care

Overview

Matthew Vesely, MD, is a dermatologist who treats psoriasis, eczema, and other autoimmune skin disorders. Dr. Vesely also sees patients with chronic skin diseases, including discoid lupus erythematosus (DLE) and hidradenitis suppurativa (HS).

“Seeing patients who have been suffering from inflammatory skin diseases for years finally get relief with the help of a targeted therapy is very rewarding,” he says.

Dr. Vesely says he enjoys working with patients and their families to find the best approach to treat a skin disorder. “I always explain that even if the first set of therapies are ineffective, we won't stop until we find the most effective treatment plan,” he says.

Dr. Vesely says he chose his specialty after learning that a large number of skin diseases caused by an overactive immune system lack FDA-approved treatments. In his research, Dr. Vesely investigates emerging new therapies that could potentially help his patients.

“Being able to research the same diseases I treat is extremely gratifying and motivating,” Dr. Vesely says.

Clinical Specialties

Dermatology

Fact Sheets

Board Certifications

  • Dermatology

    Certification Organization
    AB of Dermatology
    Original Certification Date
    2017

Yale Medicine News

Academic Achievements & Community Involvement

  • activity

    American Academy of Dermatology

  • activity

    Lupus Research Alliance

  • activity

    Society for Investigative Dermatology

  • activity

    Medical Dermatology Society

  • activity

    National Psoriasis Foundation

Get In Touch

Contacts

Appointment Number
Mailing Address

Dermatology

333 Cedar Street, LMP 5040, PO Box 208059

New Haven, CT 06520-8059

United States

Administrative Support

Locations

  • Dermatology

    Academic Office

    Hunter Building

    15 York Street, Rm HRT 603B

    New Haven, CT 06510

  • Chen Lab

    Lab

    West Campus Molecular Innovations Center

    600 West Campus Drive

    West Haven, CT 06516

  • Patient Care Locations

    Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.

Events