Genetically Informed Study Highlights Income-Independent Effect of Schizophrenia Liability on Mental and Physical Health
Kouakou M, Cabrera-Mendoza B, Pathak G, Cannon T, Polimanti R. Genetically Informed Study Highlights Income-Independent Effect of Schizophrenia Liability on Mental and Physical Health. Schizophrenia Bulletin 2024, sbae093. PMID: 38848523, DOI: 10.1093/schbul/sbae093.Peer-Reviewed Original ResearchMultivariable Mendelian randomizationMR analysisMedical endpointsMultivariable MR analysisNegative health outcomesSubstance usePsychiatric Genomics ConsortiumHigh-risk individualsFinnGen participantsMendelian randomizationMultiple testing correctionSocioeconomic inequalitiesHealth outcomesBonferroni multiple testing correctionUK BiobankSocioeconomic differencesPhysical healthMental healthAnalysis of schizophreniaGenetic liabilityAdjustment disorderHousehold incomeLife expectancyTesting correctionPersonality disorder12. Reduced P300 Responses Are Associated With Altered Excitatory and Inhibitory Cell Function in High-Risk Individuals who Convert to Psychosis: Insights From the NAPLS-2 Sample
Rodriguez-Sanchez J, Hauke D, Friston K, Cannon T, Mathalon D, Adams R. 12. Reduced P300 Responses Are Associated With Altered Excitatory and Inhibitory Cell Function in High-Risk Individuals who Convert to Psychosis: Insights From the NAPLS-2 Sample. Biological Psychiatry 2024, 95: s79. DOI: 10.1016/j.biopsych.2024.02.190.Peer-Reviewed Original ResearchAssociated with alterationsHigh-risk individualsHigh riskNAPLS-2Cell functionP300 responseAlterations