2023
The Coding Logic of Interoception
Wang R, Chang R. The Coding Logic of Interoception. Annual Review Of Physiology 2023, 86: 301-327. PMID: 38061018, PMCID: PMC11103614, DOI: 10.1146/annurev-physiol-042222-023455.Peer-Reviewed Original ResearchCardiovascular Brain Circuits
Mohanta S, Yin C, Weber C, Godinho-Silva C, Veiga-Fernandes H, Xu Q, Chang R, Habenicht A. Cardiovascular Brain Circuits. Circulation Research 2023, 132: 1546-1565. PMID: 37228235, PMCID: PMC10231443, DOI: 10.1161/circresaha.123.322791.Peer-Reviewed Original ResearchConceptsCardiovascular systemBrain circuitsAxonal connectionsCardiovascular disease progressionIntegration centerDistant brain regionsDistinct sensory neuronsEffector neuronsAfferent inputPeripheral organsDisease progressionHormone releaseSensory neuronsImmune memoryNervous systemBrain centersImmune systemBrain regionsEfferent signalsHumoral cuesDisease hypothesisArterial treeNeuronsBrainCircuit hypothesis
2022
“Goodnight” from the heart: A cardiovascular circuit that promotes sleep
Yu C, Chang R. “Goodnight” from the heart: A cardiovascular circuit that promotes sleep. Neuron 2022, 110: 3857-3859. PMID: 36480939, DOI: 10.1016/j.neuron.2022.11.005.Peer-Reviewed Original Research
2020
Vagal sensory neurons and gut-brain signaling
Yu CD, Xu QJ, Chang RB. Vagal sensory neurons and gut-brain signaling. Current Opinion In Neurobiology 2020, 62: 133-140. PMID: 32380360, PMCID: PMC7560965, DOI: 10.1016/j.conb.2020.03.006.Peer-Reviewed Original ResearchConceptsVagal sensory neuronsGut-brain signalingSensory neuronsGut-derived signalsTrans-synaptic tracingImmune controlVagus nerveImmunological disordersBrain pathwaysAnatomical basisNovel physiological functionCellular mechanismsActivity recordingsNeural activity recordingNeuronsRecent findingsNew gutPhysiological functionsGutGut systemSingle-cell genomic analysisSignalingAfferentsNervePsychological regulation