2023
Immune-Inflammatory Response And Compensatory Immune-Regulatory Reflex Systems And White Matter Integrity in Schizophrenia
Gou M, Chen W, Li Y, Chen S, Feng W, Pan S, Luo X, Tan S, Tian B, Li W, Tong J, Zhou Y, Li H, Yu T, Wang Z, Zhang P, Huang J, Kochunov P, Tian L, Li C, Hong L, Tan Y. Immune-Inflammatory Response And Compensatory Immune-Regulatory Reflex Systems And White Matter Integrity in Schizophrenia. Schizophrenia Bulletin 2023, 50: 199-209. PMID: 37540273, PMCID: PMC10754202, DOI: 10.1093/schbul/sbad114.Peer-Reviewed Original ResearchConceptsImmune-inflammatory response systemWhite matter integrityNegative symptom scoresFractional anisotropySymptom scoresAffected white matter tractsImmune inflammatory responsePanel of cytokinesWhite matter impairmentEnzyme-linked immunosorbentWhite matter tractsAverage fractional anisotropyWhite matter componentsPeripheral inflammationNeuroinflammatory conditionsPathophysiological mechanismsHealthy controlsCorpus callosumNegative symptomsReflex systemSchizophreniaOligodendrocyte differentiationConsistent findingComposite scoreUnderlying mechanism
2019
Transcriptome-wide piRNA profiling in human brains for aging genetic factors.
Mao Q, Fan L, Wang X, Lin X, Cao Y, Zheng C, Zhang Y, Zhang H, Garcia-Milian R, Kang L, Shi J, Yu T, Wang K, Zuo L, Li CR, Guo X, Luo X. Transcriptome-wide piRNA profiling in human brains for aging genetic factors. 2019, 4 PMID: 32149191, PMCID: PMC7059831.Peer-Reviewed Original ResearchPIWI-interacting RNAsTransposable elementsAge-associated genesCritical genetic determinantsGenomic integrityExpression regulationCancer stem cellsMicroarray technologyGenetic determinantsStem cellsExpression levelsRenewal capacityMolecular featuresBiological systemsPotential roleGenetic factorsYears of survivalUnderlying mechanismHuman prefrontal cortexGermlineGenesRNADisease statusMultiple testingPrefrontal cortex
2016
Central nervous system regulation of eating: Insights from human brain imaging
Farr OM, Li CS, Mantzoros CS. Central nervous system regulation of eating: Insights from human brain imaging. Metabolism 2016, 65: 699-713. PMID: 27085777, PMCID: PMC4834455, DOI: 10.1016/j.metabol.2016.02.002.Peer-Reviewed Original ResearchConceptsCentral nervous systemCentral nervous system regulationOvereating/obesityBody weight regulationNervous system regulationWeight regulationNervous systemEnergy homeostasisObesity researchAvailable evidenceBrain imagingRespective underlying mechanismsAppetiteHomeostatic controlClinical researchersUnderlying mechanismHuman brain imagingSystem regulationHuman brainExact relative contributionObesityHumansHypothalamusPathogenesisCentral role