2024
Functional Networks of Reward and Punishment Processing and Their Molecular Profiles Predicting the Severity of Young Adult Drinking
Li Y, Yang L, Hao D, Chen Y, Ye-Lin Y, Li C, Li G. Functional Networks of Reward and Punishment Processing and Their Molecular Profiles Predicting the Severity of Young Adult Drinking. Brain Sciences 2024, 14: 610. PMID: 38928610, PMCID: PMC11201596, DOI: 10.3390/brainsci14060610.Peer-Reviewed Original ResearchConnectome-based predictive modelingAlcohol use severityReward processingPunishment processingFunctional connectivityAssociated with alcohol use severityAlcohol misusePatterns of network connectivitySemi-Structured AssessmentYoung adult drinkersYoung adultsGenetics of AlcoholismYoung adult drinkingHuman Connectome Project dataNetwork connectivity featuresFronto-parietalAdult drinkersJuSpace toolboxAdult drinkingNeural fingerprintsMolecular profilingGABAA signalingRewardFunctional networksConnectivity features
2022
Problem drinking and the interaction of reward, negative emotion, and cognitive control circuits during cue-elicited craving
Le T, Chen Y, Chaudhary S, Li C. Problem drinking and the interaction of reward, negative emotion, and cognitive control circuits during cue-elicited craving. Addiction Neuroscience 2022, 1: 100004. DOI: 10.1016/j.addicn.2021.100004.Peer-Reviewed Original ResearchCognitive control circuitsPositive alcohol expectanciesNegative emotionsAlcohol use severityCognitive controlMotivational processesCue exposureAlcohol expectanciesUse severityAlcohol useAlcohol cue exposureCue-elicited cravingSocial isolationIndividual differencesReward responsesNegative reinforcementAdult drinkersEmotionsPath modelProblem drinkingActivity differencesRewardDrinking behaviorCravingControl process
2020
Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity
Li G, Zhang S, Le TM, Tang X, Li CR. Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity. Cerebral Cortex Communications 2020, 1: tgaa025. PMID: 32864617, PMCID: PMC7446303, DOI: 10.1093/texcom/tgaa025.Peer-Reviewed Original ResearchGambling TaskNeural processesImpulse controlRegional activationSex differencesDorsal anterior cingulate cortexPrefrontal cortical activationAnterior cingulate cortexReaction timeHuman Connectome ProjectCautious respondingReward sensitivityIndividual variationNeural responsesBehavioral measuresAngular gyrusLonger reaction timesPrefrontal cortexImpulsivityCingulate cortexCortical activationConnectome ProjectHigher activationTaskReward
2012
The influence of risky and conservative mental sets on cerebral activations of cognitive control
Winkler AD, Hu S, Li CS. The influence of risky and conservative mental sets on cerebral activations of cognitive control. International Journal Of Psychophysiology 2012, 87: 254-261. PMID: 22922525, PMCID: PMC3511622, DOI: 10.1016/j.ijpsycho.2012.08.010.Peer-Reviewed Original ResearchConceptsStop-signal taskMental setCognitive controlSignal taskCerebral activationPre-supplementary motor areaGo reaction timePrevious imaging workReaction timeReward uncertaintyCognitive functioningIndividual differencesStop errorGreater activationNeural responsesSalient eventsContextual effectsImaging workRetrosplenial cortexMore salientAdult participantsMotor areaSuccess trialsCerebral responsesReward