Feng Li
Associate Research ScientistCards
About
Research
Publications
2025
Synthesis of polycarbonates and polyesters via tetraalkylammonium salt-catalyzed ring-opening polymerization
Suzuki R, Takagi S, Matsuda M, Yamamoto T, Tajima K, Li F, Isono T, Satoh T. Synthesis of polycarbonates and polyesters via tetraalkylammonium salt-catalyzed ring-opening polymerization. Chemistry Letters 2025, 54: upae242. DOI: 10.1093/chemle/upae242.Peer-Reviewed Original ResearchRing-opening polymerizationRing‐opening polymerization of cyclic carbonatesSynthesis of polycarbonatesCyclic carbonatesNarrow dispersitiesCounter anionCatalytic systemCyclic estersTetraalkylammonium saltsEffective catalystNMR spectroscopyAliphatic polycarbonatesAlkyl substratesCatalytic abilityCatalytic mechanismPolyesterPolycarbonateTetraalkylammoniumDispersitiesCatalystAnionsAlkylationPolymerizationSpectroscopyEster
2024
Self-assembly of malto-oligosaccharide-block-solanesol in aqueous solutions: Investigating morphology and sugar-based physiological compatibility
Lang W, Watanabe T, Lee C, Fukushima S, Li F, Yamamoto T, Tajima K, Tagami T, Borsali R, Takahashi K, Satoh T, Isono T. Self-assembly of malto-oligosaccharide-block-solanesol in aqueous solutions: Investigating morphology and sugar-based physiological compatibility. Carbohydrate Polymers 2024, 352: 123207. PMID: 39843108, DOI: 10.1016/j.carbpol.2024.123207.Peer-Reviewed Original ResearchConceptsWorm-like structureSelf-assemblySolution self-assemblySmall-angle X-ray scatteringDynamic light scattering experimentsX-ray scatteringWorm-like micellesCo-oligomersClick chemistryTransmission electron microscopyNanopatterning applicationsLight scattering experimentsAqueous solutionLectin recognitionMicelle concentrationDiverse morphologiesScattering experimentsElectron microscopyPolarization parametersProbe methodRelaxation timeMicellesCMCGLCMorphologyFully biosourced amphiphilic block copolymer from tamarind seed xyloglucan and solanesol: synthesis, aqueous self-assembly, and drug encapsulation
Lang W, Watanabe T, Lee C, Tagami T, Li F, Yamamoto T, Tajima K, Borsali R, Takahashi K, Satoh T, Isono T. Fully biosourced amphiphilic block copolymer from tamarind seed xyloglucan and solanesol: synthesis, aqueous self-assembly, and drug encapsulation. Carbohydrate Polymers 2024, 352: 123181. PMID: 39843085, DOI: 10.1016/j.carbpol.2024.123181.Peer-Reviewed Original ResearchConceptsAqueous self-assemblyAmphiphilic block copolymersDegree of polymerizationSelf-assemblyBlock copolymersSpherical micellesNumber-average degree of polymerizationSmall-angle X-ray scatteringInvestigated block copolymersX-ray scatteringDynamic light scatteringClick chemistryTransmission electron microscopyHydrophilic blockWormlike structuresAqueous mediaCopolymersStructural analysisWater-insoluble flavonoidLight scatteringMicellesElectron microscopyDrug encapsulationHydrophobic segmentsMulti-angle dynamic light scatteringMolecular Design of a Discrete Oligosaccharide-block-Oligodimethylsiloxane System: Toward Microphase Separation with 1 nm Domain Size and Angstrom-Scale Size Control
Nishimura T, Lee C, Nunokawa R, Cheng Y, Li F, Yamamoto T, Tajima K, Borsali R, Chen H, Satoh T, Isono T. Molecular Design of a Discrete Oligosaccharide-block-Oligodimethylsiloxane System: Toward Microphase Separation with 1 nm Domain Size and Angstrom-Scale Size Control. Macromolecules 2024, 58: 266-278. DOI: 10.1021/acs.macromol.4c02262.Peer-Reviewed Original ResearchBlock copolymersDegree of polymerizationMicrophase-separated lamellar structureThiol-ene reactionSmall-angle X-ray scatteringX-ray scatteringMolecular weight distributionDimethylsiloxane unitsSynthetic accessibilityMolecular designLinker structureAngstrom-scaleMicrophase separationStructural stabilityPolymerizationLamellar structurePolymerization degreeOligodimethylsiloxaneWeight distributionDomain sizeSize controlMonomeric glucoseMicrophaseCopolymersStructureMolecular structure of enzyme-synthesized amylose-like chimeric isomaltomegalosaccharides and their encapsulation of the sulfasalazine prodrug
Lang W, Yuguchi Y, Ke C, Chang T, Kumagai Y, Kaenying W, Tagami T, Li F, Yamamoto T, Tajima K, Takahashi K, Isono T, Satoh T, Kimura A. Molecular structure of enzyme-synthesized amylose-like chimeric isomaltomegalosaccharides and their encapsulation of the sulfasalazine prodrug. Carbohydrate Polymers 2024, 349: 122956. PMID: 39638501, DOI: 10.1016/j.carbpol.2024.122956.Peer-Reviewed Original ResearchX-ray scatteringWide-angle X-ray scatteringSmall-angle X-ray scatteringPhase solubility assaysDynamic light scatteringMolecular structureCrystal structureReducing endChain lengthBinding affinityLight scatteringNonreducing terminalPresence of SZGlucoconjugatesMulti-angle dynamic light scatteringB-type crystal structureStructureConstants nCrystalline patternEncapsulationCrystallinityCrystalDrug encapsulationScatteringMoleculesPoly(butylene succinate) reinforced by small amount of grafted nanofibrillated bacterial cellulose: Toughness variability based on nanocomposites preparation method
Hashim H, Xia X, Kani H, Seno S, Li F, Isono T, Yamamoto T, Tani H, Satoh T, Tajima K. Poly(butylene succinate) reinforced by small amount of grafted nanofibrillated bacterial cellulose: Toughness variability based on nanocomposites preparation method. Composites Part A Applied Science And Manufacturing 2024, 185: 108341. DOI: 10.1016/j.compositesa.2024.108341.Peer-Reviewed Original ResearchMelt-kneadedNanofibrillated bacterial cellulosePolybutylene succinateSolvent castingHydroxypropyl celluloseNanocomposite preparation methodBacterial celluloseLow mechanical performanceMechanical performanceFlexural strengthPoly(butylene succinateReinforcing agentYoung's modulusNanocompositesBiodegradable polymersToughnessCompost biodegradation testsSurface compatibilityBiodegradation testsModulusPreparation methodDispersing agentHydrophobic moietiesCellulose-producing bacteriumCellulosePolyester Adhesives via One-Pot, One-Step Copolymerization of Cyclic Anhydride, Epoxide, and Lactide
Suzuki R, Miwa T, Nunokawa R, Sumi A, Ando M, Takahashi K, Takagi A, Yamamoto T, Tajima K, Li F, Isono T, Satoh T. Polyester Adhesives via One-Pot, One-Step Copolymerization of Cyclic Anhydride, Epoxide, and Lactide. Polymers 2024, 16: 2767. PMID: 39408477, PMCID: PMC11479215, DOI: 10.3390/polym16192767.Peer-Reviewed Original ResearchRing-opening alternating copolymerizationRing-opening polymerizationButylene oxideL-lactideOne-potGlutaric anhydrideRing-opening polymerization of l-lactideOne-step copolymerizationSelf-switchable polymerizationPolymer structural parametersPoly(l-lactideBio-based monomersCyclic anhydridesHot melt adhesivesAdhesion strengthMonomer combinationsFeed ratioConventional polymersLap shear testsAnhydrideBio-based contentCopolyestersOne-stepStructural parametersPolymerizationA Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite
Ueno M, Sugiyama H, Li F, Nishimura T, Arakawa H, Chen X, Cheng X, Takeuchi S, Takeshita Y, Takamura T, Miyagi S, Toyama T, Soga T, Masuo Y, Kato Y, Nakamura H, Tsujiguchi H, Hara A, Tajima A, Noguchi-Shinohara M, Ono K, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy M, Maeda K, Ogoshi T, Hirao A. A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite. Analytical Chemistry 2024, 96: 14499-14507. PMID: 39183562, DOI: 10.1021/acs.analchem.4c02653.Peer-Reviewed Original ResearchHost-guest complexesPhotoinduced electron transferBiological samplesHigh-throughput quantificationSupramolecular hostsElectron transferSulfonate groupsFluorescence quenchingHigh-throughput screeningCarboxyl groupsHuman urineDetection limitMass spectrometryBinding affinityBiosensorNNMT inhibitorsPillar[6]areneDirect additionSupramolecularSulfonateHuman cancer cells in vivoCarboxylQuantificationSpectrometryMetabolitesToward Fully Controllable Monomers Sequence: Binary Organocatalyzed Polymerization from Epoxide/Aziridine/Cyclic Anhydride Monomer Mixture
Gao T, Xia X, Watanabe T, Ke C, Suzuki R, Yamamoto T, Li F, Isono T, Satoh T. Toward Fully Controllable Monomers Sequence: Binary Organocatalyzed Polymerization from Epoxide/Aziridine/Cyclic Anhydride Monomer Mixture. Journal Of The American Chemical Society 2024, 146: 25067-25077. PMID: 39086123, DOI: 10.1021/jacs.4c08009.Peer-Reviewed Original ResearchRing-opening alternating copolymerizationMonomer sequenceDensity functional theory calculationsCopolymerization of epoxidesBinary catalyst systemFunctional theory calculationsBlock-like copolymerLewis acidSequence of monomersCatalyst systemCyclic anhydridesArrangement of monomersOrganocatalyzed polymerizationSynthetic methodTheory calculationsCatalytic reactionsPolymer chainsIntrinsic reactivityPoly(ester-amideBlock copolymersPolymer propertiesPolymer scienceAnhydrideCatalyst ratioMonomer mixtureOrganobase-Catalyzed Ring-Opening Copolymerization of Cyclic Anhydrides and Oxetanes: Establishment and Application in Block Copolymer Synthesis
Ota I, Suzuki R, Mizukami Y, Xia X, Tajima K, Yamamoto T, Li F, Isono T, Satoh T. Organobase-Catalyzed Ring-Opening Copolymerization of Cyclic Anhydrides and Oxetanes: Establishment and Application in Block Copolymer Synthesis. Macromolecules 2024, 57: 3741-3750. DOI: 10.1021/acs.macromol.3c02483.Peer-Reviewed Original ResearchRing-opening copolymerizationCyclic anhydridesTrimethylene oxideCyclic ethersRing-opening copolymerization of phthalic anhydridePhthalic anhydrideRing-opening polymerization of trimethylene carbonatePolymerization of trimethylene carbonatePolymerization processBlock copolymer synthesisRing-opening polymerizationSelf-switchable polymerizationPredictable molecular weightGlass transition temperatureControlled/living natureSynthesized polyestersCopolymer synthesisBlock copolymersOxetaneAnhydridePolymer materialsFunctional groupsL-lactidePolymerizationTransition temperature