Featured Publications
Low real-world eligibility rates for nonalcoholic steatohepatitis patients for phase 3 clinical trial criteria application in a large academic health system.
Ilagan-Ying YC, Xu J, Lim JK, Do A. Low real-world eligibility rates for nonalcoholic steatohepatitis patients for phase 3 clinical trial criteria application in a large academic health system. European Journal Of Gastroenterology & Hepatology 2020, 33: 424-429. PMID: 32433419, PMCID: PMC7674230, DOI: 10.1097/meg.0000000000001758.Peer-Reviewed Original ResearchConceptsUniversity-based cohortNonalcoholic steatohepatitisEnrollment criteriaLiver biopsyClinical trialsHealth system's electronic medical recordDiagnosis of NASHSystem's electronic medical recordGlobal phase 3Obeticholic acid treatmentPivotal phase 3Trial enrollment criteriaLarge academic health systemCommon liver diseaseNonalcoholic steatohepatitis patientsMultiple logistic regressionReal-world populationAcademic health systemPhase 3Electronic medical recordsMedical comorbiditiesReal-world generalizabilitySteatohepatitis patientsLaboratory abnormalitiesNASH patients
2019
Analysis of weekend effect in severe acute liver injury: A nationwide database study
Do A, Ilagan‐Ying Y, Taddei TH. Analysis of weekend effect in severe acute liver injury: A nationwide database study. Health Science Reports 2019, 3: e139. PMID: 32166187, PMCID: PMC7060892, DOI: 10.1002/hsr2.139.Peer-Reviewed Original ResearchSevere acute liver injuryAcute liver injuryHospital mortalityWeekend admissionFull model approachLiver injuryTimely managementLarge national inpatient databaseNational inpatient databaseNationwide database studyHospital-level characteristicsRevision diagnosis codesMultiple logistic regressionSignificant mortality differenceLarger hospital sizeComplete covariate dataHospital-level dataEligible hospitalizationsAdmission dayPayer databasePrimary outcomeHispanic raceMale sexPoor outcomeInpatient Database