2015
Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains
Malki K, Mineur YS, Tosto MG, Campbell J, Karia P, Jumabhoy I, Sluyter F, Crusio WE, Schalkwyk LC. Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains. BMC Genomics 2015, 16: 262. PMID: 25879669, PMCID: PMC4412144, DOI: 10.1186/s12864-015-1431-6.Peer-Reviewed Original ResearchConceptsWeighted gene coexpression network analysisGene networksGene expressionStress responseHippocampal gene expressionGene coexpression network analysisNumber of genesCandidate gene selectionCoexpression network analysisUbiquitin C geneGene expression studiesGenomic levelGENDEP projectGene pathwaysCandidate genesExpression studiesPathway analysisMolecular mechanismsC geneEnvironmental stressorsGenesGene selectionCREB1 geneBALB/cJAdverse environments
2012
Gabra5-gene haplotype block associated with behavioral properties of the full agonist benzodiazepine chlordiazepoxide
Clément Y, Prut L, Saurini F, Mineur Y, Le Guisquet A, Védrine S, Andres C, Vodjdani G, Belzung C. Gabra5-gene haplotype block associated with behavioral properties of the full agonist benzodiazepine chlordiazepoxide. Behavioural Brain Research 2012, 233: 474-482. PMID: 22677273, DOI: 10.1016/j.bbr.2012.05.041.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAnimalsBehavior, AnimalBenzodiazepinesCarrier ProteinsCerebral CortexChlordiazepoxideDose-Response Relationship, DrugGene Expression RegulationHaplotypesHippocampusMaleMaze LearningMembrane ProteinsMiceMice, Inbred C57BLMice, Mutant StrainsMotor ActivityMutationReaction TimeReceptors, GABA-ARNA, MessengerRotarod Performance TestSpace Perception