2023
Solid-Tubulocystic carcinoma: A new variant of intrahepatic cholangiocarcinoma
González I, Luo W, Zhang X. Solid-Tubulocystic carcinoma: A new variant of intrahepatic cholangiocarcinoma. World Journal Of Hepatology 2023, 15: 897-903. PMID: 37547028, PMCID: PMC10401414, DOI: 10.4254/wjh.v15.i7.897.Peer-Reviewed Original ResearchVariant of intrahepatic cholangiocarcinomaIntrahepatic cholangiocarcinomaExpression of inhibinMetastatic hepatic neoplasmsCystic growth patternDiagnostic work-upRecurrent gene fusionsModerate amount of eosinophilic cytoplasmGene fusionsAmount of eosinophilic cytoplasmImmunohistochemical profileClinicopathological featuresEosinophilic cytoplasmBiliary markersTumor cellsMorphologic spectrumHepatic massHepatic neoplasmsWork-upHepatic carcinomaVariantsYoung womenInhibinTumorCholangiocarcinoma
2021
Calcifying nested stromal–epithelial tumor: a clinicopathologic and molecular genetic study of eight cases highlighting metastatic potential and recurrent CTNNB1 and TERT promoter alterations
Papke Jr. D, Dong F, Zhang X, Kozielski R, Basturk O, Fletcher CDM, Zhao L. Calcifying nested stromal–epithelial tumor: a clinicopathologic and molecular genetic study of eight cases highlighting metastatic potential and recurrent CTNNB1 and TERT promoter alterations. Modern Pathology 2021, 34: 1696-1703. PMID: 33994539, DOI: 10.1038/s41379-021-00822-w.Peer-Reviewed Original ResearchConceptsStromal-epithelial tumorTERT promoter mutationsMetastatic diseaseCTNNB1 alterationsRare hepatic tumorRecurrent liver tumorsTERT promoter alterationsMedian tumor sizePromoter mutationsMolecular genetic featuresNuclear β-catenin expressionΒ-catenin expressionNeoadjuvant chemotherapyAbdominal metastasesLatter patientsLymphovascular invasionMedian ageLung metastasesTumor sizeHepatic tumorsNeuroendocrine markersEosinophilic cytoplasmLiver tumorsFibrous stromaTumor fibrosis