2016
Psychosocial predictors and moderators of weight management programme outcomes in ethnically diverse obese youth
Taylor JH, Xu Y, Li F, Shaw M, Dziura J, Caprio S, Tamborlane WV, Nowicka P, Savoye M. Psychosocial predictors and moderators of weight management programme outcomes in ethnically diverse obese youth. Pediatric Obesity 2016, 12: 453-461. PMID: 27384496, PMCID: PMC5568975, DOI: 10.1111/ijpo.12165.Peer-Reviewed Original ResearchConceptsClinic careObese youthOutpatient clinic careAbnormal glucose toleranceObesity treatment outcomesObesity intervention programFamily functioningLifestyle interventionGlucose toleranceChildhood obesityLifestyle programTreatment outcomesPsychosocial predictorsIdentification of factorsIntervention programsIntervention outcomesOutcomesPoor family functioningTreatment effectsHigh anxietyBaselineCareMonthsIntervention
2015
Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical Trial
Libman IM, Miller KM, DiMeglio LA, Bethin KE, Katz ML, Shah A, Simmons JH, Haller MJ, Raman S, Tamborlane WV, Coffey JK, Saenz AM, Beck RW, Nadeau KJ. Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical Trial. JAMA 2015, 314: 2241-2250. PMID: 26624824, DOI: 10.1001/jama.2015.16174.Peer-Reviewed Original ResearchConceptsType 1 diabetesBody mass indexGastrointestinal adverse eventsEffect of metforminTotal daily insulinGlycemic controlPlacebo groupOverweight adolescentsMetformin groupBaseline HbA1cAdverse eventsDaily insulinClinical trialsMultiple secondary end pointsOverweight/obese adolescentsSafety of metforminSecondary end pointsUse of metforminAddition of metforminBMI z-scoreMeasures of adipositySecondary outcomesBlood pressureInsulin dosePrimary outcomeBody Mass Index Changes in Youth in the First Year after Type 1 Diabetes Diagnosis
Gregg B, Connor CG, Ruedy KJ, Beck RW, Kollman C, Schatz D, Cengiz E, Harris B, Tamborlane WV, Klingensmith GJ, Lee JM, Consortium P. Body Mass Index Changes in Youth in the First Year after Type 1 Diabetes Diagnosis. The Journal Of Pediatrics 2015, 166: 1265-1269.e1. PMID: 25919735, DOI: 10.1016/j.jpeds.2015.02.036.Peer-Reviewed Original ResearchConceptsBody mass indexBMI z-scoreZ-scoreBody mass index (BMI) changeMeasures of BMIPediatric Diabetes ConsortiumRegain of weightFirst yearType 1 diabetesDelivery modeAdditional weight gainDiabetes durationClinical characteristicsMass indexT1D diagnosisBMI trajectoriesProspective longitudinal dataUS CentersType 1Weight gainSignificant positive changesDiagnosisMonthsSocioeconomic statusDemographic characteristics
2005
Predictors of Changes in Glucose Tolerance Status in Obese Youth
Weiss R, Taksali SE, Tamborlane WV, Burgert TS, Savoye M, Caprio S. Predictors of Changes in Glucose Tolerance Status in Obese Youth. Diabetes Care 2005, 28: 902-909. PMID: 15793193, DOI: 10.2337/diacare.28.4.902.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testImpaired glucose toleranceType 2 diabetesNormal glucose toleranceGlucose tolerance statusGlucose toleranceObese youthPredictors of changeObese childrenTolerance statusHigh riskGlucose tolerance testSevere obesityAfrican American descentTolerance testInsulin sensitivityC-peptideGlucose levelsDiabetesAnthropometric predictorsWeight changeAfrican American backgroundsPredictorsBaselineSubjects