2014
Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortex
Moore A, Zhou W, Sirois C, Belinsky G, Zecevic N, Antic S. Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: e3919-e3928. PMID: 25197082, PMCID: PMC4169969, DOI: 10.1073/pnas.1405253111.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsCalciumCerebral CortexConnexin 26ConnexinsElectrophysiological PhenomenaExtracellular SpaceFemaleFetusGap JunctionsGestational AgeHumansLanthanumMaleNeuronsSynapsesConceptsHuman fetal cortexAction potential firingFetal cortexSP neuronsSpontaneous activitySpontaneous depolarizationsYoung postmitotic neuronsGlycinergic synaptic transmissionConnexin-based gap junctionsElectrical activityAcute cortical slicesSpontaneous electrical activityWhole-cell recordingsConnexin hemichannelsGap junctionsHuman subplate neuronsPresence of connexinsSubplate neuronsSecond trimesterCortical slicesSynaptic contactsSynaptic transmissionImmunohistochemical analysisSP zonePostmitotic neurons
2012
Rapid dopaminergic and GABAergic modulation of calcium and voltage transients in dendrites of prefrontal cortex pyramidal neurons
Zhou W, Antic S. Rapid dopaminergic and GABAergic modulation of calcium and voltage transients in dendrites of prefrontal cortex pyramidal neurons. The Journal Of Physiology 2012, 590: 3891-3911. PMID: 22641784, PMCID: PMC3476639, DOI: 10.1113/jphysiol.2011.227157.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsCalciumCalcium ChannelsDendritesDopamineElectrophysiological PhenomenaGamma-Aminobutyric AcidNeuronsPrefrontal CortexPyramidal TractsRatsRats, Sprague-DawleyConceptsDendritic calcium transientsAction potentialsDopamine effectsSame dendriteCalcium transientsPrefrontal cortex pyramidal neuronsT-type calcium channel blockersDendritic calcium influxCortex pyramidal neuronsCalcium channel blockersMidbrain dopaminergic neuronsCalcium-sensitive dyeAP backpropagationDopaminergic stimulationGABAergic modulationPyramidal neuronsDopaminergic neuronsPulses of GABAD1 antagonistDopamine applicationDopaminergic suppressionDopaminergic inputSomatic excitabilityD1 agonistChannel blockers