2024
Estimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study
Hartner A, Li X, Echeverria-Londono S, Roth J, Abbas K, Auzenbergs M, de Villiers M, Ferrari M, Fraser K, Fu H, Hallett T, Hinsley W, Jit M, Karachaliou A, Moore S, Nayagam S, Papadopoulos T, Perkins T, Portnoy A, Minh Q, Vynnycky E, Winter A, Burrows H, Chen C, Clapham H, Deshpande A, Hauryski S, Huber J, Jean K, Kim C, Kim J, Koh J, Lopman B, Pitzer V, Tam Y, Lambach P, Sim S, Woodruff K, Ferguson N, Trotter C, Gaythorpe K. Estimating the health effects of COVID-19-related immunisation disruptions in 112 countries during 2020–30: a modelling study. The Lancet Global Health 2024, 12: e563-e571. PMID: 38485425, PMCID: PMC10951961, DOI: 10.1016/s2214-109x(23)00603-4.Peer-Reviewed Original ResearchConceptsCatch-up activitiesVaccine-preventable disease burdenCatch-upVaccine Impact Modelling ConsortiumImmunisation servicesMiddle-income countriesEffectiveness of HPV vaccinationVaccine effectivenessAffected cohortBill & Melinda Gates FoundationImmunisation coverageLow-incomeLong-term effectsWHO-UNICEFDisease burdenVaccination coverageCalendar yearImmunisation effortsMelinda Gates FoundationMitigation measuresCountriesYears of vaccinationYellow fever vaccine
2023
Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries
Wang P, Asare E, Pitzer V, Dubrow R, Chen K. Floods and Diarrhea Risk in Young Children in Low- and Middle-Income Countries. JAMA Pediatrics 2023, 177: 1206-1214. PMID: 37782513, PMCID: PMC10546297, DOI: 10.1001/jamapediatrics.2023.3964.Peer-Reviewed Original ResearchConceptsMiddle-income countriesDiarrhea riskOdds ratioMAIN OUTCOMEMixed-effects logistic regression modelRisk of diarrheaCross-sectional studyHigher odds ratioPrevalence of diarrheaLogistic regression modelsHealth survey programUnexposed childrenEffect modificationChild healthDiarrhea prevalenceSurvey clustersSignificant associationHygiene practicesFourth weekWeeksStrong associationRandom interceptYoung childrenChildrenDiarrheaCOVID-19 Related Immunisation Disruptions from 2020-2030: Projecting Health Impact and Mitigation Strategies for 14 Pathogens Across 112 Low- and Middle-Income Countries
Hartner A, Li X, Echeverria-Londono S, Roth J, Abbas K, Auzenbergs M, de Villiers M, Ferrari M, Fraser K, Fu H, Hallett T, Hinsley W, Jit M, Prasinou A, Moore S, Nayagam S, Papadopoulos T, Perkins T, Portnoy A, Tran Q, Vynnycky E, Winter A, Burrows H, Chen C, Clapham H, Deshpande A, Hauryski S, Huber J, Jean K, Kim C, Kim J, Koh J, Lopman B, Pitzer V, Tam Y, Lambach P, Sim S, Woodruff K, Ferguson N, Trotter C, Gaythorpe K. COVID-19 Related Immunisation Disruptions from 2020-2030: Projecting Health Impact and Mitigation Strategies for 14 Pathogens Across 112 Low- and Middle-Income Countries. 2023 DOI: 10.2139/ssrn.4492698.Peer-Reviewed Original ResearchMedical Research CouncilHuman papillomavirusVaccine preventable disease burdenYellow fever vaccinationUK Medical Research CouncilSubsets of diseaseEDCTP2 programmeImmunisation effortsHPV vaccineFever vaccinationMiddle-income countriesImmunisation coverageVaccine coverageVaccination coverageLong-term impactDisease burdenVaccination activitiesPersonal feesSanofi PasteurAdditional deathsSpeaker feesExcess deathsMRC CentreMeningitis AEpidemiologic researchPredicting indirect effects of rotavirus vaccination programs on rotavirus mortality among children in 112 countries
Kraay A, Chaney D, Deshpande A, Pitzer V, Lopman B. Predicting indirect effects of rotavirus vaccination programs on rotavirus mortality among children in 112 countries. Npj Vaccines 2023, 8: 32. PMID: 36871093, PMCID: PMC9985632, DOI: 10.1038/s41541-023-00632-y.Peer-Reviewed Original ResearchRotavirus vaccinationVaccine coveragePost-vaccine introductionHigh vaccine coverageRotavirus vaccination programLow vaccine coverageBirth rateWHO European RegionRotavirus deathsRotavirus mortalityRotavirus vaccineMiddle-income countriesVaccine impactDiarrhea deathsVaccination programIndirect protectionVaccinationEffect estimatesMortalityWestern Pacific RegionRegression analysisDirect protectionIncome countriesDeathHigh birth rate
2022
Predicting the long-term impact of rotavirus vaccination in 112 countries from 2006 to 2034: A transmission modeling analysis
Kraay A, Steele M, Baker J, Hall E, Deshpande A, Saidzosa B, Mukaratirwa A, Boula A, Mpabalwani E, Kiulia N, Tsolenyanu E, Enweronu-Laryea C, Abebe A, Beyene B, Tefera M, Willilo R, Batmunkh N, Pastore R, Mwenda J, Antoni S, Cohen A, Pitzer V, Lopman B. Predicting the long-term impact of rotavirus vaccination in 112 countries from 2006 to 2034: A transmission modeling analysis. Vaccine 2022, 40: 6631-6639. PMID: 36210251, PMCID: PMC10351612, DOI: 10.1016/j.vaccine.2022.09.072.Peer-Reviewed Original ResearchConceptsRotavirus vaccinationRotavirus positivityVaccine introductionOne-dose scheduleTwo-dose seriesRotavirus burdenRotavirus casesRotavirus gastroenteritisHospital admissionMiddle-income countriesVaccine impactVaccinated individualsLong-term impactMortality burdenPercent reductionVaccinationLife yearsIndirect protectionLow-income countriesLong-term magnitudePositivityDeathBurdenYearsIntroduction Data
2020
Meeting Report: WHO Workshop on modelling global mortality and aetiology estimates of enteric pathogens in children under five. Cape Town, 28–29th November 2018
Prudden H, Hasso-Agopsowicz M, Black R, Troeger C, Reiner R, Breiman R, Jit M, Kang G, Lamberti L, Lanata C, Lopman B, Ndifon W, Pitzer V, Platts-Mills J, Riddle M, Smith P, Hutubessy R, Giersing B. Meeting Report: WHO Workshop on modelling global mortality and aetiology estimates of enteric pathogens in children under five. Cape Town, 28–29th November 2018. Vaccine 2020, 38: 4792-4800. PMID: 32253097, PMCID: PMC7306158, DOI: 10.1016/j.vaccine.2020.01.054.Peer-Reviewed Original ResearchConceptsNumber of deathsWorld Health OrganizationEnteric diseaseEnteric pathogensVaccine Advisory CommitteeDifferent enteric pathogensDisease burden estimatesJohns Hopkins Bloomberg SchoolVaccine introduction decisionsVaccine product developmentMiddle-income countriesMortality estimatesVaccine prioritizationBurden estimatesGlobal burdenGlobal mortalityDisease estimatesBloomberg SchoolWorking GroupMajor causeHealth OrganizationHealth metricsIndependent working groupEstimation groupDeath