2022
North American Biliary Stricture Management Strategies in Children After Liver Transplantation: A Multicenter Analysis From the Society of Pediatric Liver Transplantation (SPLIT) Registry
Valentino PL, Wang T, Shabanova V, Ng VL, Bucuvalas JC, Feldman AG, Gonzalez‐Peralta R, Gupta NA, Miloh TA, Mohammad S, Pace E, Sundaram SS, Yazigi NA, Soltys K, Transplantation S. North American Biliary Stricture Management Strategies in Children After Liver Transplantation: A Multicenter Analysis From the Society of Pediatric Liver Transplantation (SPLIT) Registry. Liver Transplantation 2022, 28: 819-833. PMID: 34837468, PMCID: PMC10167704, DOI: 10.1002/lt.26379.Peer-Reviewed Original ResearchConceptsEndoscopic retrograde cholangiopancreatographyPercutaneous transhepatic cholangiographyPediatric Liver Transplantation (SPLIT) registryHepatic artery thrombosisLiver transplantationAnastomotic strictureBiliary stricturesStricture resolutionArtery thrombosisGraft survivalTransplantation RegistryPediatric liver transplantation recipientsLiver transplantation recipientsPediatric liver transplantationRisk of recurrenceAnalysis of outcomesAllograft salvageBiliary outcomesExtrahepatic stricturesGraft lossTransplantation recipientsMulticenter analysisTranshepatic cholangiographyRetrograde cholangiopancreatographyOperative reports
2019
Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections
Desai S, Aronson PL, Shabanova V, Neuman MI, Balamuth F, Pruitt CM, DePorre AG, Nigrovic LE, Rooholamini SN, Wang ME, Marble RD, Williams DJ, Sartori L, Leazer RC, Mitchell C, Shah SS. Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections. Pediatrics 2019, 144: e20183844. PMID: 31431480, PMCID: PMC6855812, DOI: 10.1542/peds.2018-3844.Peer-Reviewed Original ResearchConceptsBacteremic urinary tract infectionUrinary tract infectionAntibiotic durationParenteral antibioticsTract infectionsFrequent recurrent urinary tract infectionsYoung infantsMulticenter retrospective cohort studyRecurrent urinary tract infectionsAntibiotic therapy durationShort-course groupRetrospective cohort studyLong-course therapyMarginal structural modelsHospital reutilizationUTI recurrenceOral antibioticsCohort studyParenteral therapyPatient characteristicsTherapy durationUrine cultureChildren's HospitalWeighted populationEarly conversion
2017
Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern?
Simmons MA, Elder RW, Shabanova V, Hellenbrand W, Asnes J. Ventricular arrhythmias immediately following transcatheter pulmonary valve implantation: A cause for concern? Catheterization And Cardiovascular Interventions 2017, 91: 920-926. PMID: 29280541, DOI: 10.1002/ccd.27454.Peer-Reviewed Original ResearchConceptsTranscatheter pulmonary valve implantationRight ventricular outflow tractNative outflow tractsSignificant ventricular arrhythmiasPulmonary valve implantationVentricular arrhythmiasOutflow tractValve implantationAnti-arrhythmic medicationsBeta-blocker therapySingle-center studyVentricular outflow tractLong-term therapySudden cardiac deathCare of patientsChange of doseHemodynamic instabilityHemodynamic compromiseCardiac deathMedian ageMedical therapyPediatric patientsSignificant arrhythmiasCenter studyTerm therapyComparison of valvar and right ventricular function following transcatheter and surgical pulmonary valve replacement
Li WF, Pollard H, Karimi M, Asnes JD, Hellenbrand WE, Shabanova V, Weismann CG. Comparison of valvar and right ventricular function following transcatheter and surgical pulmonary valve replacement. Congenital Heart Disease 2017, 13: 140-146. PMID: 29148206, PMCID: PMC5796854, DOI: 10.1111/chd.12544.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBioprosthesisCardiac CatheterizationChildChild, PreschoolEchocardiographyFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHeart VentriclesHumansMaleMiddle AgedPulmonary ValvePulmonary Valve InsufficiencyRetrospective StudiesTime FactorsTreatment OutcomeVentricular Function, RightVentricular RemodelingYoung AdultConceptsRight ventricular outflow tract obstructionPulmonary valve replacementSurgical pulmonary valve replacementRight ventricular functionPulmonic insufficiencyVentricular functionTC groupRV functionSurgical groupValve replacementRV sizeVentricular outflow tract obstructionYale-New Haven HospitalOutflow tract obstructionTract obstructionPatient ageRetrospective reviewSurgical valvesPostoperative declinePulmonary valveHigh riskValve functionPatientsFirst choiceTime points
2015
Neonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci
Bizzarro MJ, Shabanova V, Baltimore RS, Dembry LM, Ehrenkranz RA, Gallagher PG. Neonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci. The Journal Of Pediatrics 2015, 166: 1193-1199. PMID: 25919728, PMCID: PMC4413005, DOI: 10.1016/j.jpeds.2015.02.009.Peer-Reviewed Original ResearchConceptsEarly-onset sepsisLate-onset sepsisNeonatal intensive care unitCoagulase-negative staphylococciIntensive care unitCare unitLevel IV neonatal intensive care unitEpisodes of sepsisLow birth weightInfection prevention initiativesInfection prevention effortsPercent of casesGroup B streptococciHospital courseSepsis episodesMost infantsBirth weightCommon organismB streptococciSepsisOutcome dataAdditional surveillancePrevention effortsStudy periodInfants
2013
Effectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana
Barry O, Powell J, Renner L, Bonney EY, Prin M, Ampofo W, Kusah J, Goka B, Sagoe K, Shabanova V, Paintsil E. Effectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana. BMC Infectious Diseases 2013, 13: 476. PMID: 24119088, PMCID: PMC3852953, DOI: 10.1186/1471-2334-13-476.Peer-Reviewed Original ResearchConceptsPediatric HIV clinicResource-limited countriesViral loadDrug-resistant mutationsVirologic failureHIV clinicFirst-line antiretroviral therapyHIV viral load monitoringCohort of HIVFirst-line ARTFirst-line regimenGenotypic resistance testingHIV viral loadInitiation of therapyType of regimenViral load monitoringSeverity of illnessViral load testingVirologic treatment failurePrimary care giversAntiretroviral therapyART regimensCD4 countTreatment failureWHO criteria
2011
“Change, before you have to.”–Jack Welch, Former CEO, General Electric*
Faustino EV, Lawson KA, Northrup V, Higgerson RA. “Change, before you have to.”–Jack Welch, Former CEO, General Electric*. Critical Care Medicine 2011, 40: 2227-2228. PMID: 21336130, PMCID: PMC3101274, DOI: 10.1097/ccm.0b013e31820eb8a1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsCase-Control StudiesCatheterization, Central VenousCause of DeathChildChild, PreschoolCritical CareCritical IllnessFemaleHospital MortalityHumansInfantIntensive Care Units, PediatricMalePrognosisReference ValuesRespiration, ArtificialRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTime FactorsTreatment OutcomeVenous ThrombosisConceptsVentilator-free daysIntensive care unitCentral venous lineDeep venous thrombosisDeep vein thrombosisIndex patientsVenous thrombosisCare unitMechanical ventilationIll childrenControl patientsVein thrombosisVenous lineIntensive care unit-free daysIntensive care unit stayPrevious prospective observational studyPediatric intensive care unitCentral venous line insertionSymptomatic venous thromboembolismVenous thrombosis studyProspective observational studyAlternative outcome measuresUnit stayVenous thromboembolismCohort study
2010
Determinants of Individual Variation in Intracellular Accumulation of Anti-HIV Nucleoside Analog Metabolites
Paintsil E, Dutschman GE, Hu R, Grill SP, Wang CJ, Lam W, Li FY, Ghebremichael M, Northrup V, Cheng YC. Determinants of Individual Variation in Intracellular Accumulation of Anti-HIV Nucleoside Analog Metabolites. Antimicrobial Agents And Chemotherapy 2010, 55: 895-903. PMID: 21078952, PMCID: PMC3028801, DOI: 10.1128/aac.01303-10.Peer-Reviewed Original ResearchConceptsNucleoside analoguesPeripheral blood mononuclear cellsAntiretroviral drug discoveryThymidine kinase 1 activityBlood mononuclear cellsConcentrations of AZTMetabolite concentrationsIntracellular concentrationAntiretroviral therapyClinical responseMononuclear cellsHealthy donorsHIV therapyTherapy needTriphosphate metaboliteAZT monophosphateAnalogue metabolitesCellular kinasesCassette (ABC) transport proteinsInverse correlationDemographic characteristicsAZTIntracellular accumulationKinase 1 activityIndividual variationA Pilot Study of Chromium Picolinate for Weight Loss
Yazaki Y, Faridi Z, Ma Y, Ali A, Northrup V, Njike VY, Liberti L, Katz DL. A Pilot Study of Chromium Picolinate for Weight Loss. Journal Of Alternative And Complementary Medicine 2010, 16: 291-299. PMID: 20192914, PMCID: PMC5206698, DOI: 10.1089/acm.2009.0286.Peer-Reviewed Original ResearchConceptsBody mass indexOverweight adultsCentral adiposityNutritional educationChromium picolinateWeight lossSimilar mean body mass indexMean body mass indexHealthy overweight adultsPlacebo-controlled trialChromium picolinate supplementationWeight loss aidPercent body fatPlacebo groupBlood pressureMass indexUrinary biomarkersOutcome measuresBody fatDaily ingestionComputerized tomographyControl groupPlaceboNutritional supplementsAdiposity
2009
Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia
Kadan-Lottick NS, Brouwers P, Breiger D, Kaleita T, Dziura J, Northrup V, Chen L, Nicoletti M, Bostrom B, Stork L, Neglia JP. Comparison of Neurocognitive Functioning in Children Previously Randomly Assigned to Intrathecal Methotrexate Compared With Triple Intrathecal Therapy for the Treatment of Childhood Acute Lymphoblastic Leukemia. Journal Of Clinical Oncology 2009, 27: 5986-5992. PMID: 19884541, PMCID: PMC2793042, DOI: 10.1200/jco.2009.23.5408.Peer-Reviewed Original ResearchMeSH KeywordsAntimetabolites, AntineoplasticAntineoplastic Combined Chemotherapy ProtocolsAttentionChildChild, PreschoolCognitionCross-Sectional StudiesCytarabineFemaleHumansHydrocortisoneInfantInjections, SpinalIntelligence TestsLinear ModelsMaleMemoryMethotrexateNeuropsychological TestsPrecursor Cell Lymphoblastic Leukemia-LymphomaPsychomotor PerformanceTime FactorsTreatment OutcomeUnited StatesConceptsAcute lymphoblastic leukemiaIT therapyIntrathecal methotrexateMethotrexate groupLymphoblastic leukemiaChildhood acute lymphoblastic leukemiaTriple intrathecal therapyPost-therapy periodLong-term neurotoxicityNeurocognitive functioningAssociation of treatmentMajority of childrenCNS prophylaxisFull-scale intelligence quotientIntrathecal therapyNeurologic eventsPsychotropic medicationsVisual-motor integrationTherapy groupAttention/concentrationNeurocognitive evaluationIndex scoreTherapyPatientsMethotrexateIntravenous Micronutrient Therapy (Myers' Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study
Ali A, Njike VY, Northrup V, Sabina AB, Williams AL, Liberti LS, Perlman AI, Adelson H, Katz DL. Intravenous Micronutrient Therapy (Myers' Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study. Journal Of Alternative And Complementary Medicine 2009, 15: 247-257. PMID: 19250003, PMCID: PMC2894814, DOI: 10.1089/acm.2008.0410.Peer-Reviewed Original ResearchConceptsQuality of lifeTender pointsFibromyalgia syndromePlacebo groupMicronutrient therapyPilot studyPlacebo-controlled pilot studyIntegrative medicine centersTender point indexMinor adverse eventsHigh placebo responseVisual analog scaleTreatment effectsSignificant differencesAlternative medicine practitionersGlobal painAdverse eventsPrimary outcomeAnalog scalePhysical functionIntervention groupPlacebo responseTeaching hospitalWeeks postinterventionOutcome measures