2020
Bayesian analysis of the epidemiology of bleeding in critically ill children
Greenway T, Eysenbach L, Shabanova V, Faustino EVS. Bayesian analysis of the epidemiology of bleeding in critically ill children. Journal Of Critical Care 2020, 63: 133-138. PMID: 33012582, PMCID: PMC8005501, DOI: 10.1016/j.jcrc.2020.09.028.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBayes TheoremChildCritical IllnessHemorrhageHumansIntensive Care Units, PediatricProspective StudiesConceptsISTH definitionIll childrenPediatric intensive care unitProspective cohort studyIntensive care unitRelevant bleedingCohort studyCare unitMechanical ventilationEntire cohortPediatric intensivistsSurvey definitionChildrenEpidemiologyInternational SocietyPrimary analytic toolsConcordanceFindingsBleedingIntensivistsThrombosisHigh frequencyHaemostasisCohortYears
2019
Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents.
Pinto MG, Shabanova V, Li S, Trakas E, Miksa M, Gertz S, Polikoff LA, Tala JA, Faustino EVS. Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents. Pediatric Critical Care Medicine 2019, 20: 907-913. PMID: 31261231, DOI: 10.1097/pcc.0000000000002018.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnticoagulantsCritical IllnessFemaleHemorrhageHumansIntensive Care Units, PediatricMaleProspective StudiesRandomized Controlled Trials as TopicRisk FactorsVenous ThromboembolismVenous ThrombosisConceptsRelevant bleedingVenous thromboembolismIll adolescentsPharmacologic prophylaxisHigh riskClinically Relevant BleedingMulticenter observational studyRandomized clinical trialsRisk of mortalityBleeding eventsTherapeutic anticoagulationMechanical ventilationPulmonary supportClinical trialsObservational studyThromboembolismBleedingAdolescents 13EpidemiologyStatistical significanceAnticoagulationProphylaxisSurgeryAdmissionAdolescents
2014
The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis
Giuliano JS, Tran K, Li FY, Shabanova V, Tala JA, Bhandari V. The Temporal Kinetics of Circulating Angiopoietin Levels in Children With Sepsis. Pediatric Critical Care Medicine 2014, 15: e1-e8. PMID: 24141659, PMCID: PMC3947338, DOI: 10.1097/pcc.0b013e3182a553bb.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAngiopoietin-1Angiopoietin-2BiomarkersCase-Control StudiesChildChild, PreschoolFemaleHumansIntensive Care Units, PediatricLength of StayMalePredictive Value of TestsProspective StudiesSepsisSeverity of Illness IndexShock, SepticSystemic Inflammatory Response SyndromeTime FactorsConceptsSevere sepsis/shockSepsis/shockSystemic inflammatory response syndrome/sepsisPediatric patientsShock groupAngiopoietin-2Day 2Angiopoietin-1Days of illnessHours of admissionIll pediatric patientsInflammatory response syndromeRisk stratification scoresProspective observational studyCritical care physiciansVascular growth factorsEnzyme-linked immunosorbentAngiopoietin levelsPICU lengthPICU patientsSevere sepsisSepsis severityResponse syndromeStratification scoresCare physicians
2011
Survey of pharmacologic thromboprophylaxis in critically ill children*
Faustino EV, Patel S, Thiagarajan RR, Cook DJ, Northrup V, Randolph AG. Survey of pharmacologic thromboprophylaxis in critically ill children*. Critical Care Medicine 2011, 39: 1773-1778. PMID: 21423003, PMCID: PMC3118917, DOI: 10.1097/ccm.0b013e3182186ec0.Peer-Reviewed Original ResearchConceptsPediatric intensive care unitIntensive care unitCare unitIll childrenPharmacologic thromboprophylaxisPediatric intensive care unit patientsIntensive care unit patientsPresence of hypercoagulabilityDeep venous thrombosisCare unit patientsEvidence-based guidelinesCross-sectional self-administered surveyRigorous randomized trialsMajor bleedingLack of evidenceUnit patientsPatient factorsVenous thrombosisCavopulmonary anastomosisRandomized trialsWeight heparinPediatric intensivistsThromboprophylaxisInfant scenarioInvasive interventions“Change, before you have to.”–Jack Welch, Former CEO, General Electric*
Faustino EV, Lawson KA, Northrup V, Higgerson RA. “Change, before you have to.”–Jack Welch, Former CEO, General Electric*. Critical Care Medicine 2011, 40: 2227-2228. PMID: 21336130, PMCID: PMC3101274, DOI: 10.1097/ccm.0b013e31820eb8a1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsCase-Control StudiesCatheterization, Central VenousCause of DeathChildChild, PreschoolCritical CareCritical IllnessFemaleHospital MortalityHumansInfantIntensive Care Units, PediatricMalePrognosisReference ValuesRespiration, ArtificialRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTime FactorsTreatment OutcomeVenous ThrombosisConceptsVentilator-free daysIntensive care unitCentral venous lineDeep venous thrombosisDeep vein thrombosisIndex patientsVenous thrombosisCare unitMechanical ventilationIll childrenControl patientsVein thrombosisVenous lineIntensive care unit-free daysIntensive care unit stayPrevious prospective observational studyPediatric intensive care unitCentral venous line insertionSymptomatic venous thromboembolismVenous thrombosis studyProspective observational studyAlternative outcome measuresUnit stayVenous thromboembolismCohort study