2020
Bayesian analysis of the epidemiology of bleeding in critically ill children
Greenway T, Eysenbach L, Shabanova V, Faustino EVS. Bayesian analysis of the epidemiology of bleeding in critically ill children. Journal Of Critical Care 2020, 63: 133-138. PMID: 33012582, PMCID: PMC8005501, DOI: 10.1016/j.jcrc.2020.09.028.Peer-Reviewed Original ResearchConceptsISTH definitionIll childrenPediatric intensive care unitProspective cohort studyIntensive care unitRelevant bleedingCohort studyCare unitMechanical ventilationEntire cohortPediatric intensivistsSurvey definitionChildrenEpidemiologyInternational SocietyPrimary analytic toolsConcordanceFindingsBleedingIntensivistsThrombosisHigh frequencyHaemostasisCohortYearsRisks of venous thrombosis and bleeding in critically ill adolescents after trauma or major surgery
Hanson SJ, Mahajerin A, Petty JK, Shabanova V, Faustino EVS. Risks of venous thrombosis and bleeding in critically ill adolescents after trauma or major surgery. Journal Of Pediatric Surgery 2020, 56: 302-308. PMID: 32713711, DOI: 10.1016/j.jpedsurg.2020.06.037.Peer-Reviewed Original ResearchConceptsCentral venous catheterizationVenous thromboembolismMajor surgeryMechanical ventilationAnatomic sitesHigh riskIll adolescentsVirtual Pediatric Systems databasePediatric intensive care unitRisk of VTERetrospective cohort studyIntensive care unitMixed-effects logistic regressionEffects logistic regressionPharmacologic prophylaxisAdjusted riskCohort studyVenous thrombosisCare unitVenous catheterizationLower riskSurgeryLevel IILogistic regressionTrauma
2019
Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents.
Pinto MG, Shabanova V, Li S, Trakas E, Miksa M, Gertz S, Polikoff LA, Tala JA, Faustino EVS. Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents. Pediatric Critical Care Medicine 2019, 20: 907-913. PMID: 31261231, DOI: 10.1097/pcc.0000000000002018.Peer-Reviewed Original ResearchConceptsRelevant bleedingVenous thromboembolismIll adolescentsPharmacologic prophylaxisHigh riskClinically Relevant BleedingMulticenter observational studyRandomized clinical trialsRisk of mortalityBleeding eventsTherapeutic anticoagulationMechanical ventilationPulmonary supportClinical trialsObservational studyThromboembolismBleedingAdolescents 13EpidemiologyStatistical significanceAnticoagulationProphylaxisSurgeryAdmissionAdolescents
2018
Factors Associated with Adverse Outcomes among Febrile Young Infants with Invasive Bacterial Infections
Pruitt CM, Neuman MI, Shah SS, Shabanova V, Woll C, Wang ME, Alpern ER, Williams DJ, Sartori L, Desai S, Leazer RC, Marble RD, McCulloh RJ, DePorre AG, Rooholamini SN, Lumb CE, Balamuth F, Shin S, Aronson PL, Collaborative F, Nigrovic L, Browning W, Mitchell C, Peaper D, Feldman E. Factors Associated with Adverse Outcomes among Febrile Young Infants with Invasive Bacterial Infections. The Journal Of Pediatrics 2018, 204: 177-182.e1. PMID: 30297292, PMCID: PMC6309646, DOI: 10.1016/j.jpeds.2018.08.066.Peer-Reviewed Original ResearchConceptsInvasive bacterial infectionsFebrile young infantsAdverse outcomesBacterial meningitisYoung infantsIll appearanceFebrile infantsBacterial infectionsRetrospective cohort studyMedical record reviewLocal microbiology laboratoryMixed-effects logistic regressionElectronic medical record systemDays of ageIll appearingNeurologic sequelaeCohort studyMedical record systemClinical factorsMedication receiptMechanical ventilationRecord reviewClinical dataInclusion criteriaMeningitisEpidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents
Faustino EVS, Shabanova V, Pinto MG, Li S, Trakas E, Miksa M, Gertz S, Polikoff LA, Napolitano M, Brudnicki AR, Tala JA, Silva CT, Investigators T, Miksa M, Taragin B, Blickman J, Taillie E, Trakas E, Balasco A, Herliczek T, Polikoff L, Dovi G, Napolitano M, Gertz S, Riordan M, Zasa J, Brudnicki A, Eldridge P, Li S, Pinto M, Faustino E, Silva C, Tala J. Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents. The Journal Of Pediatrics 2018, 201: 176-183.e2. PMID: 29891258, DOI: 10.1016/j.jpeds.2018.05.006.Peer-Reviewed Original ResearchConceptsDeep venous thrombosisExtremity deep venous thrombosisIll adolescentsVenous thrombosisFrequency of DVTLower extremity deep venous thrombosisCases of DVTBilateral deep venous thrombosisPediatric intensive care unitInvasive mechanical ventilationCentral venous catheterizationIntensive care unitPharmacologic prophylaxisTherapeutic anticoagulationCohort studyPulmonary embolismCardiopulmonary supportCare unitMechanical ventilationVenous catheterizationSevere illnessSerial sonogramsLower extremitiesEpidemiologyThrombosis
2012
Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children
Faustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, Card ME, Northrup V, Baker KE, Goodman TR, Chen L, Silva CT. Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children. The Journal Of Pediatrics 2012, 162: 387-391. PMID: 22883418, PMCID: PMC3575007, DOI: 10.1016/j.jpeds.2012.06.059.Peer-Reviewed Original ResearchConceptsCVC-related deep venous thrombosisDeep venous thrombosisCentral venous cathetersIntensive care unitAcute complicationsIll childrenVenous cathetersVenous thrombosisCare unitPediatric intensive care unitProspective cohort studyChronic complicationsHospital lengthCohort studyPatient demographicsPulmonary embolismCompression ultrasonographyMechanical ventilationHigher oddsCurrent incidenceColor DopplerComplicationsCVC characteristicsLarger studyThrombosis
2011
“Change, before you have to.”–Jack Welch, Former CEO, General Electric*
Faustino EV, Lawson KA, Northrup V, Higgerson RA. “Change, before you have to.”–Jack Welch, Former CEO, General Electric*. Critical Care Medicine 2011, 40: 2227-2228. PMID: 21336130, PMCID: PMC3101274, DOI: 10.1097/ccm.0b013e31820eb8a1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsCase-Control StudiesCatheterization, Central VenousCause of DeathChildChild, PreschoolCritical CareCritical IllnessFemaleHospital MortalityHumansInfantIntensive Care Units, PediatricMalePrognosisReference ValuesRespiration, ArtificialRetrospective StudiesRisk AssessmentSex FactorsSurvival AnalysisTime FactorsTreatment OutcomeVenous ThrombosisConceptsVentilator-free daysIntensive care unitCentral venous lineDeep venous thrombosisDeep vein thrombosisIndex patientsVenous thrombosisCare unitMechanical ventilationIll childrenControl patientsVein thrombosisVenous lineIntensive care unit-free daysIntensive care unit stayPrevious prospective observational studyPediatric intensive care unitCentral venous line insertionSymptomatic venous thromboembolismVenous thrombosis studyProspective observational studyAlternative outcome measuresUnit stayVenous thromboembolismCohort study