2024
Barriers to Effective Infection Prevention in the Neonatal Intensive Care Unit
Weser V, Crocker A, Murray T, Wright J, Truesdell E, Ciaburri R, Marks A, Martinello R, Hieftje K, Team H. Barriers to Effective Infection Prevention in the Neonatal Intensive Care Unit. Advances In Neonatal Care 2024, 24: 475-484. PMID: 39196970, DOI: 10.1097/anc.0000000000001195.Peer-Reviewed Original ResearchConceptsPatients' family membersInfection preventionFamily membersGroup of nursesReduce nurses’ burdenHand hygieneHospital-wide surveyIntensive care unitInductive content analysisDesign of educational interventionsCare unitNeonatal intensive care unitImprove patient outcomesEffective infection preventionHH educationNursing burdenEducational interventionFrontline staffHospital staffNeonatal nursesIP educationPatient's familyRisk of infection transmissionFocus groupsIP behavior
2023
Reducing MRSA Infection in a New NICU During the COVID-19 Pandemic.
Barrett R, Fleiss N, Hansen C, Campbell M, Rychalsky M, Murdzek C, Krechevsky K, Abbott M, Allegra T, Blazevich B, Dunphy L, Fox A, Gambardella T, Garcia L, Grimm N, Scoffone A, Bizzarro M, Murray T. Reducing MRSA Infection in a New NICU During the COVID-19 Pandemic. Pediatrics 2023, 151 PMID: 36625072, DOI: 10.1542/peds.2022-057033.Peer-Reviewed Original ResearchConceptsInvasive MRSA infectionsInfection prevention strategiesMethicillin-resistant Staphylococcus aureusMRSA infectionOutcome measuresPrevention strategiesCOVID-19 pandemicMultidisciplinary quality improvement initiativeLevel IV NICUSubsequent invasive infectionsMRSA colonization rateCoronavirus disease 2019 (COVID-19) pandemicHealthcare Improvement's ModelQuality improvement initiativesDisease 2019 pandemicEffectiveness of interventionsPersonal protective equipmentSupply chain shortagesHospitalized neonatesInvasive infectionsPatient daysSkin colonizationHand hygieneMost NICUsNICU
2022
A mixed-methods evaluation on the efficacy and perceptions of needleless connector disinfectants
Roberts SC, Hendrix CA, Edwards LM, Feinn RS, Martinello RA, Murray TS. A mixed-methods evaluation on the efficacy and perceptions of needleless connector disinfectants. Infection Control And Hospital Epidemiology 2022, 44: 230-233. PMID: 35387702, PMCID: PMC9929708, DOI: 10.1017/ice.2022.72.Peer-Reviewed Original ResearchMeSH Keywords2-PropanolCatheters, IndwellingChlorhexidineCross InfectionDisinfectantsDisinfectionHumansConceptsNeedleless connectorsMixed-methods evaluationNursing staffOverall bacterial burdenBloodstream infection preventionAcademic tertiary hospitalIsopropyl alcohol wipesSterile water controlTertiary hospitalNursing assessmentBacterial burdenInfection preventionImproved complianceStaff complianceChlorhexidine gluconateScrub timeConvenience sampleAlcohol wipesStaphylococcus epidermidisEfficacyProduct efficacyDry timeWipesDisinfection practicesCompliance
2019
Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit–specific NHSN definitions
Advani SD, Murray TS, Murdzek CM, Aniskiewicz MJ, Bizzarro MJ. Shifting focus toward healthcare-associated bloodstream infections: The need for neonatal intensive care unit–specific NHSN definitions. Infection Control And Hospital Epidemiology 2019, 41: 181-186. PMID: 31694731, DOI: 10.1017/ice.2019.310.Peer-Reviewed Original ResearchConceptsBloodstream infectionsNHSN definitionsNICU populationSite-specific definitionClinical definitionNational Healthcare Safety Network definitionsNeonatal intensive care unit populationIntensive care unit populationHealthcare-associated bloodstream infectionsYale-New Haven Children's HospitalLevel IV NICUSafety Network definitionsDirect prevention effortsMcNemar χ2 testSource of infectionGut translocationPreterm neonatesRespiratory supportPremature infantsRetrospective reviewChildren's HospitalPatient daysIncidence rateNICU teamUnit population
2015
The contribution of extended-spectrum &bgr;-lactamases to multidrug-resistant infections in children
Murray TS, Peaper DR. The contribution of extended-spectrum &bgr;-lactamases to multidrug-resistant infections in children. Current Opinion In Pediatrics 2015, 27: 124-131. PMID: 25565574, DOI: 10.1097/mop.0000000000000182.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsBeta-Lactam ResistanceBeta-LactamasesChildChild, PreschoolCommunity-Acquired InfectionsCross InfectionDrug Resistance, MultipleEscherichia coliEscherichia coli InfectionsGram-Negative Bacterial InfectionsHumansInfantKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsPrevalenceConceptsMultidrug-resistant infectionsGram-negative rodsProlonged fecal carriageAntibiotic prescribing practicesPrevious antibiotic useExtended-spectrum β-lactamasesCommon risk factorsThird-generation cephalosporinsDiagnostic toolAppropriate therapyChallenging infectionsPrescribing practicesNeonatal ICULaboratory criteriaNew diagnostic toolsRisk factorsAntibiotic useFecal carriageCommunity transmissionClinical implicationsInfectionCephalosporin resistanceKlebsiella pneumoniaeReporting criteriaΒ-lactamases