2023
Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging
de Havenon A, Parasuram N, Crawford A, Mazurek M, Chavva I, Yadlapalli V, Iglesias J, Rosen M, Falcone G, Payabvash S, Sze G, Sharma R, Schiff S, Safdar B, Wira C, Kimberly W, Sheth K. Identification of White Matter Hyperintensities in Routine Emergency Department Visits Using Portable Bedside Magnetic Resonance Imaging. Journal Of The American Heart Association 2023, 12: e029242. PMID: 37218590, PMCID: PMC10381997, DOI: 10.1161/jaha.122.029242.Peer-Reviewed Original ResearchConceptsWhite matter hyperintensitiesMagnetic resonance imagingSevere white matter hyperintensitiesConventional magnetic resonance imagingResonance imagingRetrospective cohortEmergency departmentMatter hyperintensitiesVascular risk factorsProspective observational studyVascular cognitive impairmentTesla magnetic resonance imagingArea Deprivation IndexProspective cohortAdult patientsAcute careRisk factorsCardiovascular diseaseObservational studyCognitive impairmentPatientsCare magnetic resonance imagingIntermodality agreementCohortDeprivation index
2022
Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus
Hehnly C, Ssentongo P, Bebell L, Burgoine K, Bazira J, Fronterre C, Kumbakumba E, Mulondo R, Mbabazi-Kabachelor E, Morton S, Ngonzi J, Ochora M, Olupot-Olupot P, Mugamba J, Onen J, Roberts D, Sheldon K, Sinnar S, Smith J, Ssenyonga P, Kiwanuka J, Paulson J, Meier F, Ericson J, Broach J, Schiff S. Cytomegalovirus infections in infants in Uganda: Newborn-mother pairs, neonates with sepsis, and infants with hydrocephalus. International Journal Of Infectious Diseases 2022, 118: 24-33. PMID: 35150915, PMCID: PMC9058984, DOI: 10.1016/j.ijid.2022.02.005.Peer-Reviewed Original ResearchConceptsNewborn-mother pairsCMV prevalenceClinical sepsisCytomegalovirus infectionCerebrospinal fluidPrevalence of CMVQuantitative PCRCMV positivityPostinfectious hydrocephalusVaginal sheddingCMV infectionHIV seropositivityNeonatal ageMaternal ageMaternal vaginalRisk factorsMedical CenterLong-term consequencesMother pairsSepsisNeonatesInfantsPrevalenceHydrocephalusCMV
2021
Vaginal microbiome topic modeling of laboring Ugandan women with and without fever
Movassagh M, Bebell L, Burgoine K, Hehnly C, Zhang L, Moran K, Sheldon K, Sinnar S, Mbabazi-Kabachelor E, Kumbakumba E, Bazira J, Ochora M, Mulondo R, Nsubuga B, Weeks A, Gladstone M, Olupot-Olupot P, Ngonzi J, Roberts D, Meier F, Irizarry R, Broach J, Schiff S, Paulson J. Vaginal microbiome topic modeling of laboring Ugandan women with and without fever. Npj Biofilms And Microbiomes 2021, 7: 75. PMID: 34508087, PMCID: PMC8433417, DOI: 10.1038/s41522-021-00244-1.Peer-Reviewed Original ResearchConceptsIntrapartum feverClinical variablesHigh prevalenceVaginal microbiomeUgandan womenLonger labour durationMaternal clinical featuresYoung maternal ageDuration of pregnancyOnset of laborMicrobial communitiesVaginal microbial communitiesAfebrile mothersFebrile mothersPeripartum courseMaternal feverNeonatal outcomesLabor durationClinical featuresMaternal ageVaginal microbesFeverOutcome riskVeillonella genusMicrobiome influences
2016
Prevalence and correlates of MRSA and MSSA nasal carriage at a Ugandan regional referral hospital
Bebell L, Ayebare A, Boum Y, Siedner M, Bazira J, Schiff S, Metlay J, Bangsberg D, Ttendo S, Firth P. Prevalence and correlates of MRSA and MSSA nasal carriage at a Ugandan regional referral hospital. Journal Of Antimicrobial Chemotherapy 2016, 72: 888-892. PMID: 27999030, PMCID: PMC5890783, DOI: 10.1093/jac/dkw472.Peer-Reviewed Original ResearchConceptsMRSA carriageMSSA carriersSA carriageNasal carriageAntibiotic useStaphylococcus aureusOpen woundsMRSA nasal carriage prevalenceUgandan Regional Referral HospitalMultivariable logistic regression analysisMSSA nasal carriageNasal carriage prevalenceSurgical ward admissionRegional Referral HospitalMRSA nasal carriageCurrent antibiotic useLogistic regression analysisResource-limited settingsMRSA carriersSA infectionsWard admissionHIV infectionReferral hospitalCarriage prevalenceAnterior nares
2014
Acceptance of brain-computer interfaces in amyotrophic lateral sclerosis
Geronimo A, Stephens H, Schiff S, Simmons Z. Acceptance of brain-computer interfaces in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2014, 16: 258-264. PMID: 25372874, DOI: 10.3109/21678421.2014.969275.Peer-Reviewed Original Research
2013
The Microbial Spectrum of Neonatal Sepsis in Uganda: Recovery of Culturable Bacteria in Mother-Infant Pairs
Kiwanuka J, Bazira J, Mwanga J, Tumusiime D, Nyesigire E, Lwanga N, Warf B, Kapur V, Poss M, Schiff S. The Microbial Spectrum of Neonatal Sepsis in Uganda: Recovery of Culturable Bacteria in Mother-Infant Pairs. PLOS ONE 2013, 8: e72775. PMID: 24013829, PMCID: PMC3754959, DOI: 10.1371/journal.pone.0072775.Peer-Reviewed Original ResearchConceptsNeonatal sepsisMother-infant pairsVaginal specimensConsecutive mother-infant pairsMicrobial spectrumSeptic newborn infantsCerebrospinal fluid culturesBacterial culture techniquesSensitive molecular approachesClinical criteriaNewborn infantsPutative causative agentFluid cultureInfant bloodMaternal bloodSepsisCerebrospinal fluidSpinal fluidInfantsBloodCausative agentMaternal transmissionEnvironmental sourcesIdentifiable bacteriaCulture techniques
2012
Visual evoked potentials for attentional gating in a brain-computer interface
Geronimo A, Schiff S, Kamrunnahar M. Visual evoked potentials for attentional gating in a brain-computer interface. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2012, 2012: 1745-1748. PMID: 23366247, PMCID: PMC3607307, DOI: 10.1109/embc.2012.6346286.Peer-Reviewed Original ResearchConceptsBrain-computer interfaceAttentional gatingMotor imagery performanceSynchronous brain computer interfacesCue primingImagery performanceCueing methodIndependent component analysisVisual cuesVoluntary modulationSubject fixationTask completionNeural signalsBCI communityBCI applicationsVEP responsesCuesPrimingTaskLow levelsParadigm
2011
A square root ensemble Kalman filter application to a motor-imagery brain-computer interface
Kamrunnahar M, Schiff S. A square root ensemble Kalman filter application to a motor-imagery brain-computer interface. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2011, 2011: 6385-6388. PMID: 22255799, PMCID: PMC5699860, DOI: 10.1109/iembs.2011.6091576.Peer-Reviewed Original Research
2010
Feature selection on movement imagery discrimination and attention detection
Dias N, Kamrunnahar M, Mendes P, Schiff S, Correia J. Feature selection on movement imagery discrimination and attention detection. Medical & Biological Engineering & Computing 2010, 48: 331-341. PMID: 20112135, PMCID: PMC2946110, DOI: 10.1007/s11517-010-0578-1.Peer-Reviewed Original Research
2009
Advances in the Application of Technology to Epilepsy: The CIMIT/NIO Epilepsy Innovation Summit
Schachter S, Guttag J, Schiff S, Schomer D, Contributors S. Advances in the Application of Technology to Epilepsy: The CIMIT/NIO Epilepsy Innovation Summit. Epilepsy & Behavior 2009, 16: 3-46. PMID: 19780225, PMCID: PMC8118381, DOI: 10.1016/j.yebeh.2009.06.028.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnticonvulsantsBrain MappingChildDrug ResistanceElectric Stimulation TherapyElectroencephalographyEngineeringEpilepsyHumansMagnetic Resonance ImagingMedical Laboratory ScienceMicroelectrodesNanoparticlesNeuronsNeurosurgeryNeurotoxinsPredictive Value of TestsSeizuresSpectroscopy, Near-InfraredTomography, Emission-Computed, Single-PhotonTomography, OpticalTranscranial Magnetic StimulationConceptsTreatment systemEvaluation of patientsTreatment of patientsGroup of cliniciansEpilepsy surgeryEngineering technologyFurther technological developmentEpilepsySeizure onset detectionPatientsEngineersSeizure predictionTechnologyApplicationsOnset detectionSurgeryCliniciansPhysiciansUnmetDiagnosis
2008
Model-based Responses and Features in Brain Computer Interfaces
Kamrunnahar M, Dias N, Schiff S, Gluckman B. Model-based Responses and Features in Brain Computer Interfaces. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2008, 2008: 4482-4485. PMID: 19163711, DOI: 10.1109/iembs.2008.4650208.Peer-Reviewed Original ResearchConceptsBrain-computer interfaceMotor imagery tasksComputer interfaceClassification errorDifferent feature selection methodsLinear discriminant analysisFeature selection methodClassification of tasksDevelopment of BCIsImagery tasksFeature extractionHuman scalp electroencephalographySelection methodRight hand movementsTaskFilter algorithmEEG signalsNovel modelPrincipal component analysisControl systems theoryHand movementsScalp EEG correlatesFeaturesInterfaceAlgorithm
2007
Comparison of EEG Pattern Classification Methods for Brain-Computer Interfaces
Dias N, Kamrunnahar M, Mendes P, Schiff S, Correia J. Comparison of EEG Pattern Classification Methods for Brain-Computer Interfaces. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2007, 2007: 2540-2543. PMID: 18002512, DOI: 10.1109/iembs.2007.4352846.Peer-Reviewed Original Research
2005
Neuronal spatiotemporal pattern discrimination: The dynamical evolution of seizures
Schiff S, Sauer T, Kumar R, Weinstein S. Neuronal spatiotemporal pattern discrimination: The dynamical evolution of seizures. NeuroImage 2005, 28: 1043-1055. PMID: 16198127, PMCID: PMC2078330, DOI: 10.1016/j.neuroimage.2005.06.059.Peer-Reviewed Original Research
2003
Interplay of Electroencephalogram Phase and Auditory-Evoked Neural Activity
Kruglikov S, Schiff S. Interplay of Electroencephalogram Phase and Auditory-Evoked Neural Activity. Journal Of Neuroscience 2003, 23: 10122-10127. PMID: 14602828, PMCID: PMC6740863, DOI: 10.1523/jneurosci.23-31-10122.2003.Peer-Reviewed Original Research
1995
Quinolinic acid in tumors, hemorrhage and bacterial infections of the central nervous system in children
Heyes M, Saito K, Milstien S, Schiff S. Quinolinic acid in tumors, hemorrhage and bacterial infections of the central nervous system in children. Journal Of The Neurological Sciences 1995, 133: 112-118. PMID: 8583213, DOI: 10.1016/0022-510x(95)00164-w.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBacterial InfectionsBiomarkersBiopterinCentral Nervous System DiseasesCentral Nervous System NeoplasmsCerebral HemorrhageChildChild, PreschoolFemaleGuanosine TriphosphateHumansHydrocephalusInfantInfant, NewbornInterleukin-6KynurenineMaleNeopterinQuinolinic AcidTryptophan OxygenaseTumor Necrosis Factor-alphaConceptsCentral nervous systemQuinolinic acidImmune activationKynurenine pathwayNervous systemBacterial infectionsLevels of QUINCentral nervous system infectionCSF QUIN levelsNervous system infectionCytokine tumor necrosisCNS inflammationNeurological deficitsSystem infectionNeurologic dysfunctionCSF levelsQUIN levelsQUIN concentrationsInterleukin-6Tumor necrosisCerebrospinal fluidNeurotoxic metabolitesSensitive markerMacrophage activationPatients
1994
Time-related patterns of ventricular shunt failure
Kast J, Duong D, Nowzari F, Chadduck W, Schiff S. Time-related patterns of ventricular shunt failure. Child's Nervous System 1994, 10: 524-528. PMID: 7882375, DOI: 10.1007/bf00335075.Peer-Reviewed Original ResearchConceptsShunt failureVentricular shunt failureVentriculoperitoneal shunt failureAge of patientsCatheter placement techniqueVentricular catheter placementNovel valve systemDistal failureDistal malfunctionProximal malfunctionConsecutive patientsProximal obstructionShunt placementCatheter placementPrimary etiologyShunt revisionShunt malfunctionSite of failureTime-related patternOverall seriesProximal failureCommon causeOutcome studiesHigh incidencePatientsSeizure control following tumor surgery for childhood cortical low-grade gliomas.
Packer R, Sutton L, Patel K, Duhaime A, Schiff S, Weinstein S, Gaillard W, Conry J, Schut L. Seizure control following tumor surgery for childhood cortical low-grade gliomas. Journal Of Neurosurgery 1994, 80: 998-1003. PMID: 8189281, DOI: 10.3171/jns.1994.80.6.0998.Peer-Reviewed Original ResearchConceptsSeizure controlPoor seizure controlLow-grade gliomasElectrocortical mappingSeizure focusTumor resectionTumor surgeryEEG monitoringLong-term seizure controlLow-grade glial tumorsPartial tumor resectionGood seizure controlHistory of seizuresExtensive tumor resectionLow-grade neoplasmsMajority of childrenCortical tumorsSeizure outcomeSurgical resectionPartial resectionTumor locationTumor removalGlial tumorsHigh riskResection