1997
Noninvasive assessment of language dominance in children and adolescents with functional MRI: a preliminary study.
Hertz-Pannier L, Gaillard W, Mott S, Cuenod C, Bookheimer S, Weinstein S, Conry J, Papero P, Schiff S, Bihan D, Theodore W. Noninvasive assessment of language dominance in children and adolescents with functional MRI: a preliminary study. Neurology 1997, 48: 1003-12. PMID: 9109891, DOI: 10.1212/wnl.48.4.1003.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingElectrostimulation mappingLeft dominanceFunctional mapping techniquesMagnetic resonance imagingNoninvasive functional mappingRight-handed childrenLanguage dominanceBilateral languageHemodynamic changesEpilepsy surgeryPartial epilepsySurgery outcomesTemporal epilepsyAmobarbital testNeuronal activationWord generation taskFrontal lobeLanguage lateralizationRight dominanceNoninvasive assessmentResonance imagingFunctional MRISignal time courseBrain development
1995
FDG-PET in children and adolescents with partial seizures: Role in epilepsy surgery,evaluation
Gaillard W, White S, MalOw B, Flamini R, Weinstein S, Sato S, Kufta C, Schiff S, Devinsky O, Fazilat S, Reeves P, Theodore W. FDG-PET in children and adolescents with partial seizures: Role in epilepsy surgery,evaluation. Epilepsy Research 1995, 20: 77-84. PMID: 7713062, DOI: 10.1016/0920-1211(94)00065-5.Peer-Reviewed Original ResearchConceptsComplex partial seizuresEEG fociPartial seizuresFDG-PETEpileptic focusGlucose metabolismRefractory complex partial epilepsyFocal MRI abnormalitiesInterictal glucose metabolismUnilateral EEG focusFDG-PET resultsFDG-PET hypometabolismComplex partial epilepsyFocal hypometabolismPET hypometabolismMRI abnormalitiesMetabolic abnormalitiesEpilepsy surgerySurgical interventionPartial epilepsyVideo-EEGEpileptogenic zonePoor responseRegional hypometabolismDrug treatment