2005
Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults
Modjarrad K, Zulu I, Redden DT, Njobvu L, Lane HC, Bentwich Z, Vermund SH. Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV-1 RNA in Coinfected Zambian Adults. The Journal Of Infectious Diseases 2005, 192: 1277-1283. PMID: 16136473, PMCID: PMC2730764, DOI: 10.1086/444543.Peer-Reviewed Original ResearchConceptsHIV-1 RNAViral loadPlasma concentrationsAntihelminthic treatmentCopies/Helminth infectionsIntestinal helminthsHigh pretreatment viral loadMedian baseline viral loadPretreatment viral loadBaseline viral loadDysfunctional immune responseIntestinal helminth infectionsHuman immunodeficiency virusMean viral loadCopies/mLHigher helminth burdensPosttreatment visitAsymptomatic adultsImmunodeficiency virusProspective studyZambian adultsUninfected groupHIV-1Immune response
2000
T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents
Douglas SD, Rudy B, Muenz L, Starr SE, Campbell DE, Wilson C, Holland C, Crowley-Nowick P, Vermund SH. T-Lymphocyte Subsets in HIV-Infected and High-Risk HIV-Uninfected Adolescents: Retention of Naive T Lymphocytes in HIV-Infected Adolescents. JAMA Pediatrics 2000, 154: 375-380. PMID: 10768676, DOI: 10.1001/archpedi.154.4.375.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCD4 Lymphocyte CountCD8-Positive T-LymphocytesFemaleHIV InfectionsHumansMaleT-Lymphocyte SubsetsVirus ReplicationConceptsHIV-negative youthHuman immunodeficiency virus-infected adolescentsT lymphocyte subsetsNaive CD8Total CD4Immune systemCell countHIV infectionAdolescent careAdolescent Medicine HIV/AIDS Research NetworkHuman immunodeficiency virus (HIV) infectionHealth ProjectActive antiretroviral therapyCohort of HIVPercentage of CD4HIV-negative controlsHIV-positive subjectsImmunodeficiency virus infectionAIDS Research NetworkHigh-risk HIVT lymphocyte responsesHIV-negative adolescentsNaive T lymphocytesMemory cell populationsSignificant increase
1999
Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents
Douglas S, Rudy B, Muenz L, Moscicki A, Wilson C, Holland C, Crowley-Nowick P, Vermund S. Peripheral blood mononuclear cell markers in antiretroviral therapy-naive HIV-infected and high risk seronegative adolescents. AIDS 1999, 13: 1629-1635. PMID: 10509563, DOI: 10.1097/00002030-199909100-00005.Peer-Reviewed Original ResearchConceptsAdolescent Medicine HIV/AIDS Research NetworkHIV-negative adolescentsHIV-negative femalesHIV-positive femalesHIV-positive adolescentsAntiretroviral therapyHIV infectionHealthy adolescentsAntiretroviral therapy-naive HIVTotal CD4 cell countsThree-color flow cytometryMononuclear cell markersNaive CD8 cellsTherapy-naive HIVCD4 cell countHIV-negative subjectsHIV-positive malesAIDS Research NetworkHigh-risk HIVCD8 memory cellsNatural killer cellsTotal leukocyte countREACH cohortSeronegative adolescentsCD8 cells
1997
Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study.
Tuomala RE, Kalish LA, Zorilla C, Fox H, Shearer W, Landay A, Vermund SH, Landesman S, Burns D. Changes in total, CD4+, and CD8+ lymphocytes during pregnancy and 1 year postpartum in human immunodeficiency virus-infected women. The Women and Infants Transmission Study. Obstetrics And Gynecology 1997, 89: 967-74. PMID: 9170476, DOI: 10.1016/s0029-7844(97)00129-4.Peer-Reviewed Original ResearchConceptsTotal lymphocyte countFirst postpartum yearLymphocyte countYear postpartumCell countCD8 percentagesNonpregnant cohortLymphocyte subsetsPostpartum yearHuman immunodeficiency virus-infected womenCD4/CD8 ratioInfants Transmission StudyHuman immunodeficiency virusImmediate postpartum periodCD4 percentMean CD4Nonpregnant HIVRelative CD4CD8 ratioAbsolute CD4Lymphocyte parametersNonpregnant womenImmunodeficiency virusPregnant womenPostpartum period