2019
Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence
Brault MA, Spiegelman D, Hargreaves J, Nash D, Vermund SH. Treatment as Prevention: Concepts and Challenges for Reducing HIV Incidence. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: s104-s112. PMID: 31658196, PMCID: PMC6820703, DOI: 10.1097/qai.0000000000002168.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV transmissionHIV plasma loadReducing HIV IncidenceHIV prevention trialsCommunity-level interventionsDeployable vaccineViral suppressionHIV testingHIV incidencePrevention trialsUninfected personsChronic conditionsHIV investmentsEarly treatmentTreat strategySexual partnersViral expressionTransmission riskHIVTrialsTreatmentInconsistent findingsPreventionSaharan Africa
2018
HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men
Dennis AM, Volz E, Frost A, Hossain M, Poon AFY, Rebeiro P, Vermund SH, Sterling TR, Kalish ML. HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men. AIDS Research And Human Retroviruses 2018, 34: 879-888. PMID: 30027754, PMCID: PMC6204570, DOI: 10.1089/aid.2018.0039.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCluster AnalysisCross-Sectional StudiesFemaleGenotypeHIV InfectionsHIV-1Homosexuality, MaleHumansMaleMiddle AgedMolecular EpidemiologyPhylogenyPol Gene Products, Human Immunodeficiency VirusRetrospective StudiesRisk FactorsRNA, ViralSequence Analysis, DNATennesseeYoung AdultConceptsYoung MSMTransmission clustersHIV-1 pol sequencesTransmission riskComprehensive Care ClinicHIV transmission patternsVanderbilt Comprehensive Care ClinicYears of ageHIV molecular epidemiologyCross-sectional analysisHigh transmission riskClinical factorsCare clinicsRisk ratioClinical dataImportance of interventionsMSM riskPol sequencesTransmission clusteringYounger ageRisk behaviorsLogistic regressionMolecular epidemiologyMSMYoung men
2010
Effect of treating co-infections on HIV-1 viral load: a systematic review
Modjarrad K, Vermund SH. Effect of treating co-infections on HIV-1 viral load: a systematic review. The Lancet Infectious Diseases 2010, 10: 455-463. PMID: 20610327, PMCID: PMC3071714, DOI: 10.1016/s1473-3099(10)70093-1.Peer-Reviewed Original ResearchConceptsViral load differencesViral loadPlasma HIV-1 RNA concentrationSystematic reviewMean plasma viral loadPlasma HIV RNA concentrationHIV-1 RNA concentrationsHIV-1 viral loadHIV RNA concentrationPlasma viral loadHIV transmission riskViral load reductionNon-pathogenic infectionsCo-infecting pathogensSyphilis treatmentHIV progressionTuberculosis treatmentEligible studiesPopulation-level benefitsTransmission riskLow-income countriesHIVTreatmentInfectionReview
1996
Limitations in characterization of heterosexual HIV transmission risk: commentary on the models of Downs and De Vincenzi.
Vermund S. Limitations in characterization of heterosexual HIV transmission risk: commentary on the models of Downs and De Vincenzi. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1996, 11: 385-7. PMID: 8601225, DOI: 10.1097/00042560-199604010-00009.Peer-Reviewed Original Research