2019
Low awareness of influenza vaccination among pregnant women and their obstetricians: a population-based survey in Beijing, China
Wang J, Sun D, Abudusaimaiti X, Vermund SH, Li D, Hu Y. Low awareness of influenza vaccination among pregnant women and their obstetricians: a population-based survey in Beijing, China. Human Vaccines & Immunotherapeutics 2019, 15: 2637-2643. PMID: 30932729, PMCID: PMC6930072, DOI: 10.1080/21645515.2019.1596713.Peer-Reviewed Original ResearchConceptsAntenatal influenza vaccinationInfluenza vaccinationPregnant womenNational Health CommissionMore high-quality trialsHigh-quality trialsBenefits of vaccinationPopulation-based surveyHistory of vaccinationChina National Health CommissionPregnant patientsAntenatal clinicInfluenza vaccineInfluenza knowledgeSame clinicVaccinationObstetriciansPregnancyHealth CommissionWomenClinicLow awarenessGovernment recommendationsRelevant evidenceQuestionnaire
2018
Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis
Zhang X, Yu Y, Yang H, Xu H, Vermund SH, Liu K. Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis. Medical Science Monitor 2018, 24: 7727-7735. PMID: 30370903, PMCID: PMC6216479, DOI: 10.12659/msm.910216.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesPregnancy outcomesCongenital syphilisPregnant womenFirst antenatal care visitEligible pregnant womenPrevention of motherAntenatal care visitsIndependent risk factorMultivariable regression analysisLogistic regression analysisRegression analysisChild transmissionMaternal syphilisAntenatal careCare visitsNeonatal asphyxiaNeonatal deathFirst trimesterRisk womenAntibody titersAntenatal testingEpidemiological characteristicsRisk factorsSyphilis diagnosisPartners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol
Audet CM, Graves E, Barreto E, De Schacht C, Gong W, Shepherd BE, Aboobacar A, Gonzalez-Calvo L, Alvim MF, Aliyu MH, Kipp AM, Jordan H, Amico KR, Diemer M, Ciaranello A, Dugdale C, Vermund SH, Van Rompaey S. Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol. Contemporary Clinical Trials 2018, 71: 63-69. PMID: 29879469, PMCID: PMC6067957, DOI: 10.1016/j.cct.2018.05.020.Peer-Reviewed Original ResearchConceptsChild transmissionSeroconcordant couplesMale partnersResource-limited rural settingsElimination of motherRoutine clinical dataUptake of servicesClinical trial designMale partner approvalAntiretroviral therapyHIV careAntenatal careRural MozambiqueHIV servicesPostnatal carePregnant womenHIV treatmentTrial protocolClinical dataHealth facilitiesTrial designHIVNewborn childrenPartner approvalEngagement interventions
2017
HIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria
Sarko KA, Blevins M, Ahonkhai AA, Audet CM, Moon TD, Gebi UI, Gana AM, Wester CW, Vermund SH, Aliyu MH. HIV status disclosure, facility-based delivery and postpartum retention of mothers in a prevention clinical trial in rural Nigeria. International Health 2017, 9: 243-251. PMID: 28810669, PMCID: PMC5881261, DOI: 10.1093/inthealth/ihx023.Peer-Reviewed Original ResearchConceptsHIV status disclosureFacility-based deliveryPostpartum retentionStatus disclosureHIV statusIntervention armWeeks postpartumChild HIV transmission (PMTCT) trialTrial intervention armPrevention of motherUnknown HIV statusPrevention clinical trialsMixed-effects logistic regressionEffects logistic regressionPMTCT continuumHIV careTreatment-naïveAntenatal carePregnant womenFacility deliveryMaternal ageObstetric servicesCare measuresClinical trialsHealth facilitiesImpact of a critical health workforce shortage on child health in Zimbabwe: a country case study on progress in child survival, 2000–2013
Haley CA, Vermund SH, Moyo P, Kipp AM, Madzima B, Kanyowa T, Desta T, Mwinga K, Brault MA. Impact of a critical health workforce shortage on child health in Zimbabwe: a country case study on progress in child survival, 2000–2013. Health Policy And Planning 2017, 32: 613-624. PMID: 28064212, PMCID: PMC5406757, DOI: 10.1093/heapol/czw162.Peer-Reviewed Original ResearchConceptsHealth workersMortality rateHealth servicesPost-natal care visitsHigh neonatal mortality rateChild health servicesLife-saving health servicesCommunity health workersNeonatal mortality rateLife-saving interventionsCommunity-based treatmentMillennium Development Goals fourLower-level cadresHealth workforce shortagesCritical shortageHigh child mortalityNational health policyCare visitsPregnant womenSenior providersHealth staffChild healthChild survivalHealth workforceChild mortality
2016
Engagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique
Audet CM, Blevins M, Chire YM, Aliyu MH, Vaz LM, Antonio E, Alvim F, Bechtel R, Wester CW, Vermund SH. Engagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique. AIDS And Behavior 2016, 20: 2090-2100. PMID: 26906021, PMCID: PMC4995150, DOI: 10.1007/s10461-016-1341-x.Peer-Reviewed Original ResearchConceptsAntenatal careHIV testingPregnant womenProvider-initiated counselingAntenatal care servicesAntiretroviral therapy servicesPre-post intervention designUptake of ARTTraditional birth attendantsMale engagementCommunity health agentsRate of testingANC servicesTreatment uptakeBirth attendantsService uptakePartner's pregnancyCare servicesTherapy servicesHealth agentsTreatment acceptabilityMale partnersSimilar interventionsMale championsPregnancy
2015
Pregnant women with HIV in rural Nigeria have higher rates of antiretroviral treatment initiation, but similar loss to follow-up as non-pregnant women and men
Aliyu MH, Blevins M, Megazzini KM, Parrish DD, Audet CM, Chan N, Odoh C, Gebi UI, Muhammad MY, Shepherd BE, Wester CW, Vermund SH. Pregnant women with HIV in rural Nigeria have higher rates of antiretroviral treatment initiation, but similar loss to follow-up as non-pregnant women and men. International Health 2015, 7: 405-411. PMID: 26012740, PMCID: PMC4654753, DOI: 10.1093/inthealth/ihv032.Peer-Reviewed Original ResearchConceptsNon-pregnant womenPregnant womenPregnancy statusCumulative incidenceART-naïve patientsEarly ART initiationPost-ART initiationAntiretroviral therapy initiationDays of enrollmentART-naïve HIVAntiretroviral treatment initiationRural NigeriaART initiationHigher CD4Therapy initiationTreatment initiationClinical stageCox regressionPatient groupPregnant clientsHIVLTFUWomenHigh rateSexHigh mobile phone ownership, but low Internet and email usage among pregnant, HIV-infected women attending antenatal care in Johannesburg
Clouse K, Schwartz SR, Van Rie A, Bassett J, Vermund SH, Pettifor AE. High mobile phone ownership, but low Internet and email usage among pregnant, HIV-infected women attending antenatal care in Johannesburg. Journal Of Telemedicine And Telecare 2015, 21: 104-107. PMID: 25586808, PMCID: PMC4860457, DOI: 10.1177/1357633x14566569.Peer-Reviewed Original ResearchConceptsHIV-positive pregnant womenMedian timePregnant womenPrevention of motherPrimary care clinicsInternet-based interventionsMobile phone interventionCurrent phone numbersAntenatal careChild transmissionMedian ageAntenatal servicesCare clinicsHigh mobile phone ownershipPhone interventionWomenHIVOne-thirdMobile phone ownershipOne-fifthInterventionYearsMobile phone numbersPhone numberSemi-structured interviews
2014
Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China
Wang AL, Qiao YP, Wang LH, Fang LW, Wang F, Jin X, Qiu J, Wang XY, Wang Q, Wu JL, Vermund SH, Song L. Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China. Bulletin Of The World Health Organization 2014, 93: 52-56. PMID: 25558108, PMCID: PMC4271682, DOI: 10.2471/blt.14.139626.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis B virusAntenatal care clinicsChild transmissionPregnant womenPMTCT servicesCare clinicsImmunodeficiency virusB virusChild transmission effortsRate of maternalChild health clinicsChild health servicesRoutine maternalHBV infectionInfected womenCongenital syphilisHIV programsGeneral HospitalHealth clinicsLive birthsFurther interventionStandardized preventionSyphilis transmissionHealth servicesCorrelates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria
Aliyu MH, Blevins M, Megazzini KM, Audet CM, Dunlap J, Sodangi IS, Gebi UI, Shepherd BE, Wester CW, Vermund SH. Correlates of Suboptimal Entry Into Early Infant Diagnosis in Rural North Central Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2014, 67: e19-e26. PMID: 24853310, PMCID: PMC4134378, DOI: 10.1097/qai.0000000000000215.Peer-Reviewed Original ResearchConceptsEarly infant diagnosisRural North-Central NigeriaInfant diagnosisPregnant womenChild HIV transmission (PMTCT) programsHIV care/treatmentClinic of enrolmentPediatric HIV infectionPrevention of motherNorth Central NigeriaMultivariable logistic regressionCare/treatmentDate of enrollmentHIV service uptakeEID uptakeCohort studyHIV infectionLaboratory variablesClinic locationService uptakeMaternal factorsTransmission programInfantsReferral sourceLogistic regression
2013
Educational Intervention Increased Referrals to Allopathic Care by Traditional Healers in Three High HIV-Prevalence Rural Districts in Mozambique
Audet CM, Salato J, Blevins M, Amsalem D, Vermund SH, Gaspar F. Educational Intervention Increased Referrals to Allopathic Care by Traditional Healers in Three High HIV-Prevalence Rural Districts in Mozambique. PLOS ONE 2013, 8: e70326. PMID: 23936407, PMCID: PMC3731350, DOI: 10.1371/journal.pone.0070326.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusReferral ratesTraditional healersHealth facilitiesNon-pregnant personsFavorable clinical outcomeHIV knowledge scoresPost-intervention ratesMonthly referral rateRural districtsClinical outcomesImmunodeficiency virusPregnant womenHIV knowledgeZambézia ProvincePatientsKnowledge scoreInexpensive interventionClinical servicesHealth systemMedian scoreEducational interventionTuberculosisCareClinicOptimizing PMTCT service delivery in rural North-Central Nigeria: Protocol and design for a cluster randomized study
Aliyu MH, Blevins M, Audet C, Shepherd BE, Hassan A, Onwujekwe O, Gebi UI, Kalish M, Lindegren ML, Vermund SH, Wester CW. Optimizing PMTCT service delivery in rural North-Central Nigeria: Protocol and design for a cluster randomized study. Contemporary Clinical Trials 2013, 36: 187-197. PMID: 23816493, PMCID: PMC3786261, DOI: 10.1016/j.cct.2013.06.013.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Retroviral AgentsCD4 Lymphocyte CountCost-Benefit AnalysisFamilyFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMaternal-Child Health CentersMentorsNigeriaPatient SatisfactionPoint-of-Care SystemsPregnancyPrenatal CareResearch DesignRural PopulationSocioeconomic FactorsConceptsAntiretroviral therapyPMTCT servicesChild transmissionHIV service integrationPMTCT service deliveryPMTCT service provisionChild HIV transmissionPrevention of motherCell count testingSimilar resource-limited settingsRural health facilitiesRural North-Central NigeriaResource-limited settingsPatient care responsibilitiesPMTCT careMore HIVHIV infectionCare CD4Cell count resultsHIV transmissionPregnant womenUNAIDS/Health facilitiesHealth providersInfluential community members
2010
Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route
Duan S, Shen S, Bulterys M, Jia Y, Yang Y, Xiang L, Tian F, Lu L, Xiao Y, Wang M, Jia M, Jiang H, Vermund SH, Jiang Y. Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route. BMC Public Health 2010, 10: 180. PMID: 20374618, PMCID: PMC2858119, DOI: 10.1186/1471-2458-10-180.Peer-Reviewed Original ResearchConceptsHIV incidenceDiscordant couplesHIV epidemicMajor drug trafficking routesRecent HIV-1 infectionAnnual HIV incidenceHIV-discordant couplesHIV-1 prevalenceHIV-1 incidenceHIV-1 infectionMigration of HIVFemale sex workersPre-marital couplesCross-sectional surveyBED IgGRecent seroconversionIntensive prevention measuresHIV-positivePregnant womenHIV preventionHigh riskResultsFrom 2004Drug usersMultivariate analysisEnzyme immunoassay
2009
Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol
Mwinga K, Vermund SH, Chen YQ, Mwatha A, Read JS, Urassa W, Carpenetti N, Valentine M, Goldenberg RL. Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol. BMC Pediatrics 2009, 9: 49. PMID: 19664210, PMCID: PMC2746190, DOI: 10.1186/1471-2431-9-49.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsBlood Cell CountDouble-Blind MethodFemaleFollow-Up StudiesGestational AgeHematocritHemoglobinsHIVHIV InfectionsHumansIncidenceInfantInfant, NewbornMalawiNevirapinePregnancyPregnancy Complications, InfectiousRetrospective StudiesRNA, ViralTanzaniaTreatment OutcomeYoung AdultZambiaConceptsHIV infectionPregnant African womenRandomized clinical trialsTime of laborComplete laboratory dataWeeks of ageNevirapine prophylaxisChild transmissionHIV exposureWeeks' gestationHIV statusPregnant womenNewborn infantsClinical trialsPublic clinicsHIVInfantsBiochemical measurementsCaucasian populationWomenLaboratory dataNormative dataAfrican womenInfectionWeeksPreventing HIV in Developing Countries: Status of Biomedical Interventions
Vermund S. Preventing HIV in Developing Countries: Status of Biomedical Interventions. The FASEB Journal 2009, 23: 199.1-199.1. DOI: 10.1096/fasebj.23.1_supplement.199.1.Peer-Reviewed Original ResearchHIV Prevention Trials NetworkPrevention of motherHIV drug resistanceNeedle exchange programsDNA boostBehavior changeHIV seroconversionHIV seroincidenceEarly therapyPregnant womenHSV-2Clinical trialsHIVMale circumcisionDrug addiction treatmentDrug resistanceTrials NetworkAddiction treatmentBiomedical interventionsSeroincidenceInfantsRisk reductionTherapyPrevention challengesEfficacy
2008
Do Targeted HIV Programs Improve Overall Care for Pregnant Women?
Potter D, Goldenberg RL, Chao A, Sinkala M, Degroot A, Stringer JS, Bulterys M, Vermund SH. Do Targeted HIV Programs Improve Overall Care for Pregnant Women? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2008, 47: 79-85. PMID: 17984757, PMCID: PMC2745056, DOI: 10.1097/qai.0b013e31815d2f71.Peer-Reviewed Original ResearchConceptsPrevalence odds ratiosHIV programsPMTCT programme implementationChild HIV transmissionPrevention of motherConfidence intervalsRoutine clinical servicesDisease-specific researchHealth policy makersAntenatal clinicSyphilis treatmentHIV transmissionPregnant womenOverall careOdds ratioFirst visitCare impactClinical servicesService programsImplementation of researchScreeningProgram implementationClinicVisitsCare
2007
Use of Traditional Medicine among Pregnant Women in Lusaka, Zambia
Banda Y, Chapman V, Goldenberg RL, Stringer JS, Culhane JF, Sinkala M, Vermund SH, H. B. Use of Traditional Medicine among Pregnant Women in Lusaka, Zambia. Journal Of Alternative And Complementary Medicine 2007, 13: 123-128. PMID: 17309386, DOI: 10.1089/acm.2006.6225.Peer-Reviewed Original ResearchMeSH KeywordsAdultClinical Trials as TopicFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansMaternal BehaviorMaternal Health ServicesMedicine, African TraditionalPatient Acceptance of Health CarePregnancyPregnancy Complications, InfectiousPrevalenceSeroepidemiologic StudiesSurveys and QuestionnairesZambiaConceptsPregnant womenTraditional healersTraditional medicineHuman immunodeficiency virus (HIV) prevention strategiesWorse medical careHealth care providersTraditional medicine usePublic health systemAntiretroviral regimensCurrent pregnancyMedical regimenHIV transmissionMedicine useHIV knowledgeClinical trialsPostpartum questionnaireCare providersPrevention strategiesSex partnersMedical carePrior useHealth systemDry sexPregnancyWomen
2006
Correlates of Syphilis Seroreactivity Among Pregnant Women: The HIVNET 024 Trial in Malawi, Tanzania, and Zambia
Potter D, Goldenberg RL, Read JS, Wang J, Hoffman IF, Saathoff E, Kafulafula G, Aboud S, Martinson FE, Dahab M, Vermund SH. Correlates of Syphilis Seroreactivity Among Pregnant Women: The HIVNET 024 Trial in Malawi, Tanzania, and Zambia. Sexually Transmitted Diseases 2006, 33: 604-609. PMID: 16601659, PMCID: PMC2743105, DOI: 10.1097/01.olq.0000216029.00424.ae.Peer-Reviewed Original ResearchConceptsSub-Saharan African settingHistory of stillbirthCross-sectional studyMultisite clinical trialSyphilis preventionSyphilis seroprevalenceSyphilis seroreactivityAntenatal attendeesPreterm deliveryYoung HIVAntenatal HIVHIV infectionPregnant womenSyphilis screeningRisk factorsClinical trialsUlcer treatmentHigh riskHIVAge 20African settingWomenSignificant correlatesTrialsCorrelatesUse of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes
Goldenberg RL, McClure EM, Saleem S, Rouse D, Vermund S. Use of Vaginally Administered Chlorhexidine During Labor to Improve Pregnancy Outcomes. Obstetrics And Gynecology 2006, 107: 1139-1146. PMID: 16648420, DOI: 10.1097/01.aog.0000215000.65665.dd.Peer-Reviewed Original ResearchConceptsPregnancy outcomesHuman immunodeficiency virusExcellent safety profileGroup B streptococciUse of chlorhexidineChild transmissionNeonatal sepsisNeonatal infectionChlorhexidine useVaginal treatmentImmunodeficiency virusNeonatal mortalityPregnant womenSafety profileAdverse outcomesNewborn periodSTUDY SELECTIONB streptococciPromising treatmentChlorhexidine treatmentBacterial loadChlorhexidineEffective killersEnglish literatureFurther studies
2004
Marginal validity of syndromic management for reproductive tract infections among pregnant women in Jamaica
Hylton-Kong T, Brathwaite AR, Del Rosario GR, Kristensen S, Kamara P, Jolly PE, Hook EW, Figueroa JP, Vermund SH. Marginal validity of syndromic management for reproductive tract infections among pregnant women in Jamaica. International Journal Of STD & AIDS 2004, 15: 371-375. PMID: 15186580, DOI: 10.1258/095646204774195209.Peer-Reviewed Original ResearchConceptsReproductive tract infectionsSyndromic managementPregnant womenAntenatal clinicTract infectionsSyndromic case management approachAntenatal care facilitiesHigh-risk womenAffordable diagnostic testsPositive predictive valueCase management approachAntenatal attendersClinical algorithmClinical careCare facilitiesPredictive valueJamaican womenDiagnostic testsLaboratory supportWomenClinicInfectionLow sensitivityCervicitisCandidiasis