2024
Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies
Buchanan A, Hernández-Ramírez R, Lok J, Vermund S, Friedman S, Forastiere L, Spiegelman D. Assessing Direct and Spillover Effects of Intervention Packages in Network-randomized Studies. Epidemiology 2024, 35: 481-488. PMID: 38709023, DOI: 10.1097/ede.0000000000001742.Peer-Reviewed Original ResearchIntervention packageEffectiveness of interventional packageImprove intervention deliveryPeer education interventionHIV prevention trialsPeer educator trainingMarginal structural modelsPublic health impactHIV risk behaviorsIntervention deliveryIntervention NetworkEducational interventionParticipant visitsPrevention trialsFollow-up visitRisk behaviorsHealth impactsInterventionEducational trainingParticipantsSpillover effectsVisitsHIVExposed networksPeer
2023
Overall, Direct, Spillover, and Composite Effects of Components of a Peer-Driven Intervention Package on Injection Risk Behavior Among People Who Inject Drugs in the HPTN 037 Study
Hernández-Ramírez R, Spiegelman D, Lok J, Forastiere L, Friedman S, Latkin C, Vermund S, Buchanan A. Overall, Direct, Spillover, and Composite Effects of Components of a Peer-Driven Intervention Package on Injection Risk Behavior Among People Who Inject Drugs in the HPTN 037 Study. AIDS And Behavior 2023, 28: 225-237. PMID: 37932493, PMCID: PMC11062514, DOI: 10.1007/s10461-023-04213-x.Peer-Reviewed Original ResearchInjection risk behaviorsPeer education interventionRisk behaviorsClinical trial registrationSubsequent risk behaviorsTRIAL REGISTRATIONOutcome ratesSecondary data analysisIndex individualsRoutine evaluationIntervention componentsIntervention NetworkMixed effects modelsIntervention packageGroups/networksPeer education trainingPeer educatorsOverall rateInterventionPeer educationEffects modelTraining sessionsDrugsControl conditionBehavioral measures
2022
Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda
Sileo K, Wanyenze R, Anecho A, Luttinen R, Semei C, Mukasa B, Musoke W, Vermund S, Dworkin S, Dovidio J, Taylor B, Kershaw T. Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda. Pilot And Feasibility Studies 2022, 8: 264. PMID: 36564795, PMCID: PMC9783690, DOI: 10.1186/s40814-022-01202-0.Peer-Reviewed Original ResearchHIV care engagementHIV outcomesCare engagementViral load suppressionPilot intervention trialPatient-provider relationshipEffective clinical interventionsPreliminary evidenceEvidence-based strategiesHIV providersHIV counselingHIV disparitiesHIV treatmentIntervention trialsControl clinicsImplementation strategiesProvider outcomesClinical interventionsProvider capacityTrialsGender-responsive treatmentInterventionOutcomesPatientsTreatmentDoes Voluntary Medical Male Circumcision Reduce HIV Risk in Men Who Have Sex with Men?
Lin Y, Gao Y, Sun Y, Turner D, Zou H, Vermund S, Qian H. Does Voluntary Medical Male Circumcision Reduce HIV Risk in Men Who Have Sex with Men? Current HIV/AIDS Reports 2022, 19: 522-525. PMID: 36520379, DOI: 10.1007/s11904-022-00637-7.Peer-Reviewed Original ResearchConceptsVoluntary medical male circumcisionRandomized clinical trialsHIV riskMedical male circumcisionPurpose of ReviewToSubgroup of menHIV prevalenceClinical trialsAnal sexMale circumcisionPopulation-level impactAvailable evidenceMSMInsertive roleConflicting resultsMenSexRiskOriginal studyEfficacyInterventionEvidenceReviewToStrong evidencePrevalence
2021
Community-based health workers implementing universal access to HIV testing and treatment: lessons from South Africa and Zambia—HPTN 071 (PopART)
Viljoen L, Mainga T, Casper R, Mubekapi-Muzadaidzwa C, Wademan D, Bond V, Pliakas T, Bwalya C, Stangl A, Phiri M, Yang B, Shanaube K, Bock P, Fidler S, Hayes R, Ayles H, Hargreaves J, Hoddinott G, Seeley J, Donnell D, Floyd S, Mandla N, Bwalya J, Sabapathy K, Eshleman S, Macleod D, Moore A, Vermund S, Hauck K, Shanaube K. Community-based health workers implementing universal access to HIV testing and treatment: lessons from South Africa and Zambia—HPTN 071 (PopART). Health Policy And Planning 2021, 36: 881-890. PMID: 33963387, PMCID: PMC8227454, DOI: 10.1093/heapol/czab019.Peer-Reviewed Original ResearchConceptsCommunity-based health workersHIV testingHealth workersHIV prevention packageHPTN 071 (PopART) trialHIV epidemic controlPopulation health benefitsPopART interventionCHW interventionPrevention packageTreatment servicesIntervention staffTrial outcomesBaseline quantitative dataReferral servicesCHW retentionHealth benefitsIntervention packageProcess evaluationEpidemic controlGroup discussionsInterventionTrialsKey informant interviewsEmotional support
2019
From surviving to thriving: the role of resilience in meeting global HIV goals.
Harrison SE, Li X, Vermund SH. From surviving to thriving: the role of resilience in meeting global HIV goals. AIDS 2019, 33 Suppl 1: s1-s4. PMID: 31397717, PMCID: PMC7024581, DOI: 10.1097/qad.0000000000002242.Peer-Reviewed Original ResearchConceptsResilience-based interventionsRole of resiliencePositive adaptationHealth-related domainsCurrent conceptualizationsHIV care continuumPsychosocial aspectsPublic health strategiesVulnerable individualsHIV populationHIV treatmentCare continuumResilienceHealth strategiesHIVPeopleScientific studiesTreatmentGlobal targetsConceptualizationGlobal fightPopulationIndividualsInterventionAttention
2018
Exploration of Implementation Patterns and Content from a Text-Based Outreach Intervention Clinical Trial for Newly Diagnosed, HIV-Positive MSM in Beijing, China
Knudson A, Shaw S, Yin L, Xiao D, Qian HZ, Sullivan S, Liu H, Ruan Y, Shao Y, Vermund SH, Amico KR. Exploration of Implementation Patterns and Content from a Text-Based Outreach Intervention Clinical Trial for Newly Diagnosed, HIV-Positive MSM in Beijing, China. AIDS And Behavior 2018, 23: 1158-1165. PMID: 30288683, PMCID: PMC6566097, DOI: 10.1007/s10461-018-2287-y.Peer-Reviewed Original ResearchAssessing Individual and Disseminated Effects in Network-Randomized Studies
Buchanan AL, Vermund SH, Friedman SR, Spiegelman D. Assessing Individual and Disseminated Effects in Network-Randomized Studies. American Journal Of Epidemiology 2018, 187: 2449-2459. PMID: 30052722, PMCID: PMC6211234, DOI: 10.1093/aje/kwy149.Peer-Reviewed Original Research
2017
Adapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique
Audet CM, Salato J, Vermund SH, Amico KR. Adapting an adherence support workers intervention: engaging traditional healers as adherence partners for persons enrolled in HIV care and treatment in rural Mozambique. Implementation Science 2017, 12: 50. PMID: 28407813, PMCID: PMC5390357, DOI: 10.1186/s13012-017-0582-z.Peer-Reviewed Original ResearchConceptsCommunity health workersAntiretroviral therapyWorker interventionTraditional healersHealth workersHealth systemAllopathic health systemEvidence-informed interventionsLow-literacy populationsHIV careHIV diagnosisRural MozambiquePatient adherenceHIV epidemicHealth facilitiesClinical careHealthcare providersHealth workforceHIVTraditional treatmentCommunity-based activitiesInterventionTraditional medicineCareSuccessful program implementation
2016
Seeking Male Sexual Partners via Internet and Traditional Venues among Chinese Men Who Have Sex with Men: Implications for HIV Risk Reduction Interventions
Liu Y, Wang J, Qian HZ, Liu H, Yin L, Lu H, Zhang C, Ruan Y, Shao Y, Vermund SH. Seeking Male Sexual Partners via Internet and Traditional Venues among Chinese Men Who Have Sex with Men: Implications for HIV Risk Reduction Interventions. AIDS And Behavior 2016, 20: 2222-2230. PMID: 27000143, PMCID: PMC7784627, DOI: 10.1007/s10461-016-1371-4.Peer-Reviewed Original ResearchConceptsMale sexual partnersChinese menSexual partnersHIV risk reduction interventionsCondomless receptive anal sexReceptive anal sexRisk reduction interventionsBehaviors of MSMCross-sectional surveyHigh-risk behaviorsHIV epidemicChinese MSMAnal sexReduction interventionsMSMSociodemographic predictorsLonger durationSexMenInterventionHigher incomeHIVTraditional venues
2015
High mobile phone ownership, but low Internet and email usage among pregnant, HIV-infected women attending antenatal care in Johannesburg
Clouse K, Schwartz SR, Van Rie A, Bassett J, Vermund SH, Pettifor AE. High mobile phone ownership, but low Internet and email usage among pregnant, HIV-infected women attending antenatal care in Johannesburg. Journal Of Telemedicine And Telecare 2015, 21: 104-107. PMID: 25586808, PMCID: PMC4860457, DOI: 10.1177/1357633x14566569.Peer-Reviewed Original ResearchConceptsHIV-positive pregnant womenMedian timePregnant womenPrevention of motherPrimary care clinicsInternet-based interventionsMobile phone interventionCurrent phone numbersAntenatal careChild transmissionMedian ageAntenatal servicesCare clinicsHigh mobile phone ownershipPhone interventionWomenHIVOne-thirdMobile phone ownershipOne-fifthInterventionYearsMobile phone numbersPhone numberSemi-structured interviews
2014
Modeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China
Lou J, Blevins M, Ruan Y, Vermund SH, Tang S, Webb GF, Shepherd BE, He X, Lu H, Shao Y, Qian HZ. Modeling the Impact on HIV Incidence of Combination Prevention Strategies among Men Who Have Sex with Men in Beijing, China. PLOS ONE 2014, 9: e90985. PMID: 24626165, PMCID: PMC3953201, DOI: 10.1371/journal.pone.0090985.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyHIV epidemicCondom useHIV prevalenceART coverageCombination prevention strategiesHIV/AIDSHIV testingHIV incidenceCombination interventionsBeijing MSMPrevention strategiesPrevalence estimatesPrevalenceEpidemic expansionMenInterventionEpidemicIncidenceBasic reproduction numberPrevention scenariosCurrent coverageSexReproduction numberIntervention levels
2012
Effectiveness of Integrated HIV Prevention Interventions among Chinese Men Who Have Sex with Men: Evaluation of a 16-City Public Health Program
Ye S, Xiao Y, Jin C, Cassell H, Blevins M, Sun J, Vermund SH, Qian HZ. Effectiveness of Integrated HIV Prevention Interventions among Chinese Men Who Have Sex with Men: Evaluation of a 16-City Public Health Program. PLOS ONE 2012, 7: e50873. PMID: 23300528, PMCID: PMC3534092, DOI: 10.1371/journal.pone.0050873.Peer-Reviewed Original ResearchConceptsPublic health programsSelf-reported receiptHIV prevalenceCondom useHealth programsLast sexMultivariable logistic regression analysisMale partnersLow HIV prevalenceHIV prevention interventionsLogistic regression analysisYearly cross-sectional surveysSelf-reported condom useCross-sectional surveyHIV infectionIndependent predictorsHIV epidemicMSM populationPrevention interventionsChinese menDisease ratesEffective interventionsPrevalenceInterventionSex
2010
Combination HIV Prevention: Significance, Challenges, and Opportunities
Kurth AE, Celum C, Baeten JM, Vermund SH, Wasserheit JN. Combination HIV Prevention: Significance, Challenges, and Opportunities. Current HIV/AIDS Reports 2010, 8: 62-72. PMID: 20941553, PMCID: PMC3036787, DOI: 10.1007/s11904-010-0063-3.Peer-Reviewed Original ResearchConceptsHIV prevention strategiesHIV transmissionPrevention strategiesPopulation-level HIV transmissionBehavioral risk reductionEvidence-based strategiesNumber of interventionsAntiretroviral medicationsHIV serostatusPrevention packageUninfected personsEpidemiologic profileHIV pandemicMale circumcisionNeedle exchangeEffective interventionsTarget populationInterventionRisk reductionMeasurable reductionPopulation levelDiverse subgroupsMedicationsSerostatusHIVRethinking Prevention of HIV Type 1 Infection
Burns DN, Dieffenbach CW, Vermund SH. Rethinking Prevention of HIV Type 1 Infection. Clinical Infectious Diseases 2010, 51: 725-731. PMID: 20707698, PMCID: PMC3071685, DOI: 10.1086/655889.Peer-Reviewed Original Research
2005
An Intervention to Reduce Vaginal Douching Among Adolescent and Young Adult Women: A Randomized, Controlled Trial
Grimley DM, Oh MK, Desmond RA, Hook EW, Vermund SH. An Intervention to Reduce Vaginal Douching Among Adolescent and Young Adult Women: A Randomized, Controlled Trial. Sexually Transmitted Diseases 2005, 32: 752-758. PMID: 16314772, DOI: 10.1097/01.olq.0000190018.58079.05.Peer-Reviewed Original ResearchConceptsVaginal douchingYoung adult womenAdult womenIndividualized counseling sessionsTreat modelPrimary outcome measureStage of readinessSecondary outcomesIntervention groupOutcome measuresStages of changeHealthy eatingStage-matched interventionsYoung womenDouchingYoung adultsComparison groupWomenMonthsCounseling sessionsInterventionExperimental groupTrialsCessationComparison conditionParents’/guardians’ willingness to vaccinate their children against genital herpes
Liddon N, Pulley L, Cockerham WC, Lueschen G, Vermund SH, Hook EW. Parents’/guardians’ willingness to vaccinate their children against genital herpes. Journal Of Adolescent Health 2005, 37: 187-193. PMID: 16109337, DOI: 10.1016/j.jadohealth.2005.05.030.Peer-Reviewed Original ResearchConceptsHSV-2Type 2 vaccineLogistic regression modelsParents/guardiansInfluenza shotSTD vaccinesCorrelates of intentionGenital herpesMajority of parentsVaccine acceptanceDisease vaccineVaccinationLogistic regressionOptimal timingFuture interventionsVaccineAppropriate timingSexual activityTelephone surveyChildrenParents' acceptanceInterventionOne-thirdDescriptive statisticsOverall attitude
2004
Tolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025
Wilson CM, Gray G, Read JS, Mwatha A, Lala S, Johnson S, Violari A, Sibiya PM, Fleming TR, Koonce A, Vermund SH, McIntyre J. Tolerance and Safety of Different Concentrations of Chlorhexidine for Peripartum Vaginal and Infant Washes: HIVNET 025. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2004, 35: 138-143. PMID: 14722445, PMCID: PMC2753236, DOI: 10.1097/00126334-200402010-00006.Peer-Reviewed Original ResearchConceptsChris Hani Baragwanath HospitalPrevention of motherHIV Type 1Solution of chlorhexidineConcentrations of chlorhexidineChild transmissionBaragwanath HospitalMaternal symptomsPrevention trialsThird trimesterClinical indicationsMaternity unitsSubjective complaintsVaginal areaWash groupType 1ChlorhexidineInfant examinationWomenSustainable interventionsTolerable concentrationInterventionMothersWashDifferent concentrations
2002
Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies.
Stringer JS, Sinkala M, Rouse DJ, Goldenberg RL, Vermund SH. Effect of nevirapine toxicity on choice of perinatal HIV prevention strategies. American Journal Of Public Health 2002, 92: 365-6. PMID: 11867311, PMCID: PMC1447080, DOI: 10.2105/ajph.92.3.365.Peer-Reviewed Original ResearchTransmission of HIV
Kristensen S, Sinkala M, Vermund S. Transmission of HIV. 2002, 217-230. DOI: 10.1007/0-306-47817-x_13.Peer-Reviewed Original ResearchSafe male circumcisionSustained antiretroviral therapyTransmission of HIVProportion of infectionsSexual partner numberAntiretroviral therapyHIV vaccineSexual exposureHIV preventionSTD treatmentHuman studiesMale circumcisionCondom useMale partnersBehavioral interventionsPartner numbersEmployment-related exposureInterventionHIVAdditional strategiesLower ratesHigh rateLimited valueSaharan AfricaExposure