2023
Combination HIV prevention during pregnancy and the post‐partum period in Malawi and Zambia: a mathematical modelling analysis
Powers K, Mutale W, Rosenberg N, Graybill L, Mollan K, Freeborn K, Saidi F, Maman S, Mulenga P, Jahn A, Nyirenda R, Stringer J, Vermund S, H. B. Combination HIV prevention during pregnancy and the post‐partum period in Malawi and Zambia: a mathematical modelling analysis. Journal Of The International AIDS Society 2023, 26: e26128. PMID: 37403422, PMCID: PMC10320044, DOI: 10.1002/jia2.26128.Peer-Reviewed Original ResearchConceptsFemale HIV transmissionMaternal HIV acquisitionMaternal HIV incidenceHIV prevention strategiesPost-partum periodAntiretroviral therapyHIV transmissionMale partnersHIV acquisitionHIV incidenceANC patientsPrevention strategiesCombination HIV prevention strategiesCombination HIV prevention interventionSuppressive antiretroviral therapyPre-exposure prophylaxisVertical HIV transmissionAntenatal care programsCombination HIV preventionHIV prevention interventionsANC initiationART initiationUnsuppressed HIVIncident infectionsUndiagnosed HIV
2022
Voluntary Medical Male Circumcision to Reduce HIV Acquisition and Transmission
Vermund S. Voluntary Medical Male Circumcision to Reduce HIV Acquisition and Transmission. Current HIV/AIDS Reports 2022, 19: 471-473. PMID: 36478080, PMCID: PMC10767716, DOI: 10.1007/s11904-022-00631-z.Peer-Reviewed Original ResearchConceptsHIV acquisitionVoluntary medical male circumcisionHIV infection acquisitionVoluntary medical male circumcision (VMMC) programsMinor surgical interventionsMale circumcision programsHIV incidence ratesHigh HIV prevalenceMedical male circumcisionFirst clinical trialUninfected menHIV incidenceHIV prevalenceInfection acquisitionSaharan AfricaSurgical interventionCircumcision programsClinical trialsIncidence ratePreventive benefitsHIV riskCircumcision ratesRecent FindingsSinceMale circumcisionHealth section
2020
An unrecognized key population? Traditional treatment practices associated with HIV risk among traditional healers in rural South Africa.
Audet CM, Ngobeni S, Mkansi M, Wafawanaka F, Aliyu MH, Vermund SH, Wagner RG. An unrecognized key population? Traditional treatment practices associated with HIV risk among traditional healers in rural South Africa. AIDS 2020, 34: 2313-2317. PMID: 33048882, PMCID: PMC7674239, DOI: 10.1097/qad.0000000000002710.Peer-Reviewed Original ResearchConceptsSkin incisionPatient's bloodHIV testTraditional healersHIV prevalenceKey populationsRapid HIV testsRisk of acquisitionHigh HIV prevalenceBlood-borne pathogensTraditional treatment practicesSouth African traditional healersPositive test resultsCross-sectional surveyPersonal protective equipmentHIV acquisitionHIV infectionPosttest counselingPretest counselingHIV riskOccupational exposureMAIN OUTCOMERural South AfricaHIVAfrican traditional healersIncident HIV among pregnant and breast-feeding women in sub-Saharan Africa: a systematic review and meta-analysis.
Graybill LA, Kasaro M, Freeborn K, Walker JS, Poole C, Powers KA, Mollan KR, Rosenberg NE, Vermund SH, Mutale W, Chi BH. Incident HIV among pregnant and breast-feeding women in sub-Saharan Africa: a systematic review and meta-analysis. AIDS 2020, 34: 761-776. PMID: 32167990, PMCID: PMC7275092, DOI: 10.1097/qad.0000000000002487.Peer-Reviewed Original ResearchConceptsBreast-feeding womenMaternal HIV incidenceHIV incidenceHIV acquisitionIncidence rateHIV preventionSystematic reviewHigh HIV incidencePartner's HIV statusHIV incidence ratesCombination HIV preventionNonpregnant periodsIncident HIVTreatment landscapeHIV statusSaharan AfricaElevated riskSummary estimatesRelevant conferencesIncidenceAverage incidenceLimited evidenceWomenCalendar timePrevention
2019
Modeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China
Zhang C, Penson DF, Qian HZ, Webb GF, Lou J, Shephard BE, Liu Y, Vermund SH. Modeling economic and epidemiological impact of voluntary medical male circumcision among men who have sex with men in Beijing, China. International Journal Of STD & AIDS 2019, 30: 630-638. PMID: 30890118, PMCID: PMC6666307, DOI: 10.1177/0956462419831859.Peer-Reviewed Original ResearchConceptsVoluntary medical male circumcisionNew HIV casesMedical male circumcisionHIV casesMale circumcisionHIV/AIDS epidemicCoverage rateHIV acquisitionHIV incidenceCumulative numberCircumcision ratesDeterministic compartmental modelEpidemiological impactVMMC implementationAIDS epidemicMenMSMCircumcisionSexYearsCompartmental modelCasesIncidence
2018
Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China
Yin L, Zhao Y, Peratikos MB, Song L, Zhang X, Xin R, Sun Z, Xu Y, Zhang L, Hu Y, Hao C, Ruan Y, Shao Y, Vermund SH, Qian HZ. Risk Prediction Score for HIV Infection: Development and Internal Validation with Cross-Sectional Data from Men Who Have Sex with Men in China. AIDS And Behavior 2018, 22: 2267-2276. PMID: 29786768, PMCID: PMC7024582, DOI: 10.1007/s10461-018-2129-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingChinaCondomsCross-Sectional StudiesHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceRisk AssessmentRisk FactorsRisk-TakingSafe SexSexual and Gender MinoritiesSexual BehaviorSexual PartnersSurveys and QuestionnairesSyphilisUnsafe SexYoung AdultConceptsHIV infectionRisk scoreHuman immunodeficiency virus (HIV) riskMultivariable logistic regression modelingBootstrap-corrected C-indexMultiple male sexual partnersValid risk scoreVaccine clinical trialsHigh-risk MSMHigh-risk personsRisk prediction scoreReceptive anal intercourseReceptive anal sexInconsistent condom useMale sexual partnersHIV prevention programmingLogistic regression modelingDrug/alcohol addictionHIV acquisitionRisk reduction programsSyphilis infectionHIV prevalenceClinical trialsC-indexIllegal drug use
2016
C-107 Stigma and depression among newly diagnosed HIV infected MSM in China
Tao J, Wang L, Kipp A, Qian H, Yin L, Ruan Y, Shao Y, Lu H, Vermund S. C-107 Stigma and depression among newly diagnosed HIV infected MSM in China. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 71: 49. DOI: 10.1097/01.qai.0000479593.51216.ff.Peer-Reviewed Original ResearchInternalized stigmaRisk factorsStigma scoresRandomized clinical trialsAntiretroviral therapyHIV acquisitionPotential social isolationHIV diagnosisHospital AnxietyCare continuumClinical trialsDepression ScaleChinese MSMHigh riskHIVExploratory factor analysisStigma ScaleLogistic regressionMedian scoreBaseline surveyMSMStrong associationDepressionSocial isolationScores
2013
Can Combination Prevention Strategies Reduce HIV Transmission in Generalized Epidemic Settings in Africa? The HPTN 071 (PopART) Study Plan in South Africa and Zambia
Vermund SH, Fidler SJ, Ayles H, Beyers N, Hayes RJ. Can Combination Prevention Strategies Reduce HIV Transmission in Generalized Epidemic Settings in Africa? The HPTN 071 (PopART) Study Plan in South Africa and Zambia. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2013, 63: s221-s227. PMID: 23764639, PMCID: PMC3739051, DOI: 10.1097/qai.0b013e318299c3f4.Peer-Reviewed Original ResearchConceptsHIV Prevention Trials NetworkHPTN 071 (PopART) studyHPTN 071HIV incidenceHIV transmissionHome-based HIV testingVoluntary medical male circumcisionGeneralized epidemic settingsLinkage of HIVUniversal antiretroviral therapyChild HIV transmissionPrevention of motherHIV viral loadCommunity health workersMedical male circumcisionCommunity-randomized trialIntervention strategiesCombination prevention strategiesAntiretroviral therapyHIV acquisitionSeropositive personsTuberculosis servicesHIV testingViral loadTuberculosis transmission
2009
Willingness to Be Circumcised for Preventing HIV among Chinese Men Who Have Sex with Men
Ruan Y, Qian HZ, Li D, Shi W, Li Q, Liang H, Yang Y, Luo F, Vermund SH, Shao Y. Willingness to Be Circumcised for Preventing HIV among Chinese Men Who Have Sex with Men. AIDS Patient Care And STDs 2009, 23: 315-321. PMID: 19335172, PMCID: PMC2743100, DOI: 10.1089/apc.2008.0199.Peer-Reviewed Original ResearchConceptsClinical trialsChinese MSMChinese menMale circumcisionEffectiveness of circumcisionLack of historyUncircumcised MSMHIV acquisitionHIV/Genital hygieneAdult circumcisionFree medical servicesTight foreskinSide effectsSexual partnersInfection riskMSMCircumcisionPreventing HIVMedical servicesTrialsMenHeterosexual menCommunity educationSexHIV Incidence Rates and Risk Factors for Urban Women in Zambia: Preparing for a Microbicide Clinical Trial
Kapina M, Reid C, Roman K, Cyrus-Cameron E, Kwiecien A, Weiss S, Vermund SH. HIV Incidence Rates and Risk Factors for Urban Women in Zambia: Preparing for a Microbicide Clinical Trial. Sexually Transmitted Diseases 2009, 36: 129-133. PMID: 19174729, PMCID: PMC2889146, DOI: 10.1097/olq.0b013e318190191d.Peer-Reviewed Original ResearchConceptsHigh HIV prevalenceHIV prevalenceHIV incidenceIncidence rateHighest age-specific prevalenceHuman immunodeficiency virus (HIV) incidencePreparedness studiesBaseline HIV prevalenceRisk reduction counselingAge-specific prevalenceHIV incidence ratesMicrobicide clinical trialsWomen yearsSexual behavioral characteristicsPopulation of womenSame study proceduresGeneral population sampleHIV acquisitionReduction counselingEligible womenHIV/Infection testingRisk factorsClinical trialsPregnancy rate
2003
Comparison of Two Strategies for Administering Nevirapine to Prevent Perinatal HIV Transmission in High-Prevalence, Resource-Poor Settings
Stringer JS, Sinkala M, Stout JP, Goldenberg RL, Acosta EP, Chapman V, Kumwenda-Phiri R, Vermund SH. Comparison of Two Strategies for Administering Nevirapine to Prevent Perinatal HIV Transmission in High-Prevalence, Resource-Poor Settings. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2003, 32: 506-513. PMID: 12679702, PMCID: PMC2745994, DOI: 10.1097/00126334-200304150-00007.Peer-Reviewed Original ResearchConceptsHigh-prevalence settingsClinic AClinic BVCT servicesPrevent Perinatal HIV TransmissionPerinatal HIV acquisitionPerinatal HIV preventionPerinatal HIV transmissionKnowledge of serostatusResource-poor settingsNevirapine therapyNVP therapyHIV acquisitionHIV testingHIV statusHIV transmissionPregnant womenCord bloodHIV preventionHigh prevalenceInfant deathUniversal therapyClinicTherapyMaternal reports