2020
Linked-read sequencing identifies abundant microinversions and introgression in the arboviral vector Aedes aegypti
Redmond S, Sharma A, Sharakhov I, Tu Z, Sharakhova M, Neafsey D. Linked-read sequencing identifies abundant microinversions and introgression in the arboviral vector Aedes aegypti. BMC Biology 2020, 18: 26. PMID: 32164699, PMCID: PMC7068900, DOI: 10.1186/s12915-020-0757-y.Peer-Reviewed Original ResearchMeSH KeywordsAedesAnimalsChromosome InversionChromosomesGenetic IntrogressionGenetic VariationHigh-Throughput Nucleotide SequencingMosquito VectorsConceptsChromosomal inversionsFuture population genetic studiesRelated sister speciesPolytene chromosome analysisArboviral vector Aedes aegyptiLinked-read sequencingPopulation genetic studiesChromosome banding patternsHost-feeding preferencesAedes aegyptiPhenotypic divergenceSister speciesSecondary contactChromosomal diversityDeep Illumina sequencingDipteran insectsRepetitive genomesIllumina sequencingFeeding preferencesGenomic rearrangementsHost preferenceSequencing dataVector Aedes aegyptiGenetic studiesSubspecies
2019
In Silico Karyotyping of Chromosomally Polymorphic Malaria Mosquitoes in the Anopheles gambiae Complex
Love R, Redmond S, Pombi M, Caputo B, Petrarca V, della Torre A, Consortium T, Besansky N. In Silico Karyotyping of Chromosomally Polymorphic Malaria Mosquitoes in the Anopheles gambiae Complex. G3: Genes, Genomes, Genetics 2019, 9: 3249-3262. PMID: 31391198, PMCID: PMC6778791, DOI: 10.1534/g3.119.400445.Peer-Reviewed Original ResearchConceptsInversion genotypesSingle nucleotide polymorphismsInversion polymorphismTag single nucleotide polymorphismsChromosomal inversion polymorphismTag SNP genotypesAnopheles gambiae complexParacentric inversion polymorphismEnvironmental heterogeneityChromosomal rearrangementsImportant phenotypesMalaria mosquitoesSilico karyotypingNatural variationGambiae complexMosquito speciesTraditional cytogeneticsCytogenetic methodsBiallelic genotypesSignificant vectorSNP genotypesGonotrophic stagesNucleotide polymorphismsGenomeHuman malaria