2015
Association mapping by pooled sequencing identifies TOLL 11 as a protective factor against Plasmodium falciparum in Anopheles gambiae
Redmond S, Eiglmeier K, Mitri C, Markianos K, Guelbeogo W, Gneme A, Isaacs A, Coulibaly B, Brito-Fravallo E, Maslen G, Mead D, Niare O, Traore S, Sagnon N, Kwiatkowski D, Riehle M, Vernick K. Association mapping by pooled sequencing identifies TOLL 11 as a protective factor against Plasmodium falciparum in Anopheles gambiae. BMC Genomics 2015, 16: 779. PMID: 26462916, PMCID: PMC4603968, DOI: 10.1186/s12864-015-2009-z.Peer-Reviewed Original ResearchConceptsGenetic mappingFounder coloniesHigh nucleotide diversityNon-model genomesLow linkage disequilibriumPhenotype-genotype mappingPopulation stratificationParasite infection levelsHuman malaria parasiteGenotyping of SNPsNucleotide diversityPooled sequencesAssociation mappingGenomic lociLinkage mappingPlasmodium falciparumSignificant SNPsMosquito systemMarker densityDNA poolsAnopheles gambiaeNatural variationIndividual mosquitoesLinkage disequilibriumSequencing identifies
2012
Transcriptome of the adult female malaria mosquito vector Anopheles albimanus
Martínez-Barnetche J, Gómez-Barreto R, Ovilla-Muñoz M, Téllez-Sosa J, López D, Dinglasan R, Mohien C, MacCallum R, Redmond S, Gibbons J, Rokas A, Machado C, Cazares-Raga F, González-Cerón L, Hernández-Martínez S, López M. Transcriptome of the adult female malaria mosquito vector Anopheles albimanus. BMC Genomics 2012, 13: 207. PMID: 22646700, PMCID: PMC3442982, DOI: 10.1186/1471-2164-13-207.Peer-Reviewed Original ResearchConceptsMalaria vectorsProtein-coding transcriptsAvailable genomic informationPlasmodium-mosquito interactionsHigh-quality assemblyImportant malaria vectorAnopheles albimanusFemale transcriptomesPutative orthologsDivergence timesPlasmodium lifecycleEukaryotic genomesTranscriptome projectsEvolutionary biologyInterPro annotationProtein familyMosquito biologyInsect vectorsGenomic informationNeotropical vectorsCDNA libraryIllumina sequencesAnopheline mosquito vectorsGenus AnophelesFat body
2011
VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
Megy K, Emrich S, Lawson D, Campbell D, Dialynas E, Hughes D, Koscielny G, Louis C, MacCallum R, Redmond S, Sheehan A, Topalis P, Wilson D, . VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics. Nucleic Acids Research 2011, 40: d729-d734. PMID: 22135296, PMCID: PMC3245112, DOI: 10.1093/nar/gkr1089.Peer-Reviewed Original ResearchConceptsBioinformatics resourcesHigh-throughput dataPopulation geneticsTaxonomic coverageInsecticide resistance dataGenome browserGenomic variationInvertebrate vectorsGenomic featuresBiology resourcesExpression dataHuman pathogensTsetse fliesGenomeBody liceTimely releaseVectorBaseGenomicsGeneticsBioinformaticsFliesMultiple typesAnnotationLicePathogens
2010
SNP Genotyping Defines Complex Gene-Flow Boundaries Among African Malaria Vector Mosquitoes
Neafsey D, Lawniczak M, Park D, Redmond S, Coulibaly M, Traoré S, Sagnon N, Costantini C, Johnson C, Wiegand R, Collins F, Lander E, Wirth D, Kafatos F, Besansky N, Christophides G, Muskavitch M. SNP Genotyping Defines Complex Gene-Flow Boundaries Among African Malaria Vector Mosquitoes. Science 2010, 330: 514-517. PMID: 20966254, PMCID: PMC4811326, DOI: 10.1126/science.1193036.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesFemaleGene FlowGenes, InsectGenotypeInsect VectorsMalariaPolymorphism, Single NucleotideConceptsGenomic differentiationGenome-wide monitoringGreater genetic divergenceVector mosquito populationsMalaria vector mosquitoesAfrican malaria vector mosquitoesReproductive isolationBehavioral diversificationGenetic divergenceGenomic regionsNatural selectionPopulation structurePolymorphic inversionsSelective eventsSNP genotypingVector control effortsMosquito populationsVector mosquitoesDifferentiationComplex showDivergenceMosquitoesCentromeresGenomeSpecies
2006
VectorBase: a home for invertebrate vectors of human pathogens
Lawson D, Arensburger P, Atkinson P, Besansky N, Bruggner R, Butler R, Campbell K, Christophides G, Christley S, Dialynas E, Emmert D, Hammond M, Hill C, Kennedy R, Lobo N, MacCallum M, Madey G, Megy K, Redmond S, Russo S, Severson D, Stinson E, Topalis P, Zdobnov E, Birney E, Gelbart W, Kafatos F, Louis C, Collins F. VectorBase: a home for invertebrate vectors of human pathogens. Nucleic Acids Research 2006, 35: d503-d505. PMID: 17145709, PMCID: PMC1751530, DOI: 10.1093/nar/gkl960.Peer-Reviewed Original Research