Featured Publications
Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia.
Redeker N, Conley S, O'Connell M, Geer J, Yaggi H, Jeon S. Sleep-related predictors of cognition among adults with chronic insomnia and heart failure enrolled in a randomized controlled trial of cognitive behavioral therapy for insomnia. Journal Of Clinical Sleep Medicine 2023, 19: 1073-1081. PMID: 36740924, PMCID: PMC10235706, DOI: 10.5664/jcsm.10498.Peer-Reviewed Original ResearchConceptsChronic heart failureCognitive behavioral therapyHeart failureGroup time effectsRest-activity rhythmBehavioral therapyChronic insomniaCBT-I groupSelf-reported cognitive functionProportion of participantsTrial of CBTQuality of lifeSelf-management strategiesGroup-based CBTWalk distanceSleep apneaChronic illnessWrist actigraphyCognitive impairmentInsomniaTherapyCognitive functionMinute walkSelf-reported cognitive abilitiesBaseline cognitionRest-activity rhythms predict time to hospitalizations and emergency department visits among participants in a randomized control of adults with heart failure and insomnia
Jeon S, Conley S, Hollenbeak C, O'Connell M, Wang Z, Tocchi C, Redeker N. Rest-activity rhythms predict time to hospitalizations and emergency department visits among participants in a randomized control of adults with heart failure and insomnia. Sleep Medicine 2023, 108: 1-7. PMID: 37301192, PMCID: PMC10336725, DOI: 10.1016/j.sleep.2023.05.019.Peer-Reviewed Original ResearchConceptsRest-activity rhythmED visitsHeart failureEmergency departmentCircadian quotientEarly hospitalizationWrist actigraphyEarly ED visitsChronic heart failureLow ejection fractionFirst cardiac eventCox proportional hazardsEffects of insomniaCognitive behavioral therapyComposite eventsNYHA classHF patientsCardiac eventsCPAP useSevere painEjection fractionMale sexSevere insomniaHospitalizationInsomnia severityTrajectory of self-care in people with stable heart failure and insomnia after two self-care interventions
Conley S, Jeon S, Andrews L, Breazeale S, Hwang Y, O'Connell M, Linsky S, Redeker N. Trajectory of self-care in people with stable heart failure and insomnia after two self-care interventions. Patient Education And Counseling 2022, 105: 3487-3493. PMID: 36088189, DOI: 10.1016/j.pec.2022.09.001.Peer-Reviewed Original ResearchConceptsStable heart failureSelf-care interventionsHeart failureSevere baseline fatigueSelf-care supportSelf-care educationSelf-care groupEffects of CBTCognitive behavioral therapyGroup-based trajectory modelingBaseline fatigueEfficacious interventionsHealthcare providersSecondary analysisInsomniaBehavioral therapySelf-CareChi-squareDemographic characteristicsInterventionT-testFunctional performanceAdultsTrajectory modelingFailureSymptom Cluster Profiles Among Adults with Insomnia and Heart Failure
Conley S, Jeon S, Breazeale S, O’Connell M, Hollenbeak CS, Jacoby D, Linsky S, Yaggi HK, Redeker NS. Symptom Cluster Profiles Among Adults with Insomnia and Heart Failure. Behavioral Sleep Medicine 2022, 21: 150-161. PMID: 35388730, PMCID: PMC9537348, DOI: 10.1080/15402002.2022.2060226.Peer-Reviewed Original ResearchConceptsHigh symptom burdenHeart failureSymptom burdenSleep characteristicsLower symptom burdenChronic heart failureStable heart failureBody mass indexTreatment of insomniaStudy of insomniaHigh symptom profileCognitive behavioral therapyBeta blockersClinical characteristicsDaytime symptomsMass indexSevere insomniaSingle symptomInsomnia severitySymptom profilesInsomniaSymptom clustersBehavioral therapyHigher symptomsSymptomsCognitive behavioral therapy for insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: the HeartSleep Study
Redeker NS, Yaggi HK, Jacoby D, Hollenbeak CS, Breazeale S, Conley S, Hwang Y, Iennaco J, Linsky S, Nwanaji-Enwerem U, O’Connell M, Jeon S. Cognitive behavioral therapy for insomnia has sustained effects on insomnia, fatigue, and function among people with chronic heart failure and insomnia: the HeartSleep Study. Sleep 2021, 45: zsab252. PMID: 34657160, PMCID: PMC8754495, DOI: 10.1093/sleep/zsab252.Peer-Reviewed Original ResearchConceptsChronic heart failureSix-minute walk distanceStable heart failureHeart failureInsomnia severityWalk distanceSleep characteristicsSelf-reported sleep latencyGeneral linear mixed modelSelf-reported sleep characteristicsMonths of treatmentSelf-management educationSelf-management programSleep hygiene educationCognitive behavioral therapyEjection fractionPrimary outcomeDaytime symptomsExcessive daytimePhysical functionDaytime sleepinessSleep latencyMild insomniaSleep qualitySleep efficiencyRest-activity rhythms, daytime symptoms, and functional performance among people with heart failure
Jeon S, Conley S, Redeker NS. Rest-activity rhythms, daytime symptoms, and functional performance among people with heart failure. Chronobiology International 2020, 37: 1223-1234. PMID: 32588662, PMCID: PMC7529895, DOI: 10.1080/07420528.2020.1779280.Peer-Reviewed Original ResearchConceptsRest-activity rhythmStable heart failureHeart failureDaytime symptomsCircadian quotientPoorer New York Heart Association classNew York Heart Association classHF disease management programFunctional performanceBetter NYHA classChronic heart failureMinute walk testDisease management programsLess sleep fragmentationHF independentUnattended polysomnographyNYHA classGreater comorbidityAssociation classWalk testIntra-daily variabilityFunctional outcomePhysical functionPoor functionSleep fragmentationDiscrepancy between wrist‐actigraph and polysomnographic measures of sleep in patients with stable heart failure and a novel approach to evaluating discrepancy
Jeon S, Conley S, Redeker NS. Discrepancy between wrist‐actigraph and polysomnographic measures of sleep in patients with stable heart failure and a novel approach to evaluating discrepancy. Journal Of Sleep Research 2018, 28: e12717. PMID: 29943403, PMCID: PMC6309769, DOI: 10.1111/jsr.12717.Peer-Reviewed Original ResearchConceptsPoor sleep qualityTotal sleep timeHeart failurePolysomnographic measuresSleep qualitySleep measuresSleep timeHeart failure disease management programsMotor activityDaytime motor activityStable heart failureShorter total sleep timeCross-sectional studyPoor sleep efficiencyImportance of agingDisease management programsOlder patientsBland-Altman plotsSevere insomniaRisk factorsClinical dataIntra-class correlationSleep characteristicsSleep efficiencyWrist actigraphyEffects of Cognitive Behavioral Therapy for Insomnia on Sleep-Related Cognitions Among Patients With Stable Heart Failure
Redeker NS, Jeon S, Andrews L, Cline J, Mohsenin V, Jacoby D. Effects of Cognitive Behavioral Therapy for Insomnia on Sleep-Related Cognitions Among Patients With Stable Heart Failure. Behavioral Sleep Medicine 2017, 17: 342-354. PMID: 28745520, PMCID: PMC5904007, DOI: 10.1080/15402002.2017.1357120.Peer-Reviewed Original ResearchConceptsEffects of CBTHF patientsSleep disturbance questionnaireCognitive behavioral therapySleep-related cognitionsStable New York Heart Association class IINew York Heart Association class IIInsomnia severityChronic heart failure patientsBehavioral therapyPittsburgh Sleep Quality IndexHigh symptom burdenStable heart failureHeart failure patientsSleep Quality IndexImproved sleep qualityInsomnia Severity IndexSelf-reported fatigueDysfunctional sleep-related cognitionsSymptom burdenFailure patientsHeart failureMixed-effects modelingSleep latencyPoor sleepSleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure
Jeon S, Redeker NS. Sleep Disturbance, Daytime Symptoms, and Functional Performance in Patients With Stable Heart Failure. Nursing Research 2016, 65: 259-267. PMID: 27362512, PMCID: PMC4930009, DOI: 10.1097/nnr.0000000000000169.Peer-Reviewed Original ResearchConceptsSelf-reported functional performanceStable heart failureDaytime symptomsHeart failureSleep disturbancesNew York Heart Association class ISix-minute walk testFunctional performanceRespiratory disturbance indexPoorer functional performanceHF patientsSymptom burdenWalk testRespiratory indexObservational studySleep qualityInsomnia symptomsAmbulatory polysomnographyPatientsSecondary analysisSymptomsClass IDisturbance indexExploratory regression analysisRegression analysis
2022
Correlates of cognition among people with chronic heart failure and insomnia
Geer JH, Jeon S, O’Connell M, Linsky S, Conley S, Hollenbeak CS, Jacoby D, Yaggi HK, Redeker NS. Correlates of cognition among people with chronic heart failure and insomnia. Sleep And Breathing 2022, 27: 1287-1296. PMID: 36214945, PMCID: PMC10084469, DOI: 10.1007/s11325-022-02716-w.Peer-Reviewed Original ResearchConceptsChronic heart failureHigher body mass indexHeart failureBody mass indexQuality of lifeMass indexDaytime sleepinessNew York Heart Association class ICognitive impairmentSignificant risk factorsNon-white raceSelf-reported cognitive impairmentInsomnia Severity IndexSleep disturbance questionnaireCross-sectional analysisCognitive behavioral therapyFrequency of lapsesMedical comorbiditiesCommon comorbiditiesClinical factorsEjection fractionPulmonary diseaseMultivariable analysisRisk factorsSleep characteristicsTreatment Fidelity in a Randomized Controlled Trial of Cognitive Behavioral Therapy for Insomnia in Heart Failure
O’Connell M, Iennaco JD, Linsky S, Jeon S, Conley S, Gaiser E, Redeker NS. Treatment Fidelity in a Randomized Controlled Trial of Cognitive Behavioral Therapy for Insomnia in Heart Failure. Nursing Research 2022, 71: 459-468. PMID: 35997691, PMCID: PMC9617756, DOI: 10.1097/nnr.0000000000000616.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapySleep disturbance questionnaireTreatment fidelityDysfunctional beliefsBehavioral therapyDisturbance QuestionnaireSleep-related beliefsCBT-I interventionTrial of CBTMost participantsNap frequencyChronic insomniaSleep scheduleSleep behaviorSleep onsetSleep ScaleSleep efficiencySleep itemsCBTBeliefsEfficacious treatmentTotal scoreFidelity evaluationHeart failureInsomniaCoping, symptoms, and insomnia among people with heart failure during the COVID-19 pandemic
O’Connell M, Jeon S, Conley S, Linsky S, Redeker NS. Coping, symptoms, and insomnia among people with heart failure during the COVID-19 pandemic. European Journal Of Cardiovascular Nursing 2022, 22: 291-298. PMID: 35938348, PMCID: PMC9384676, DOI: 10.1093/eurjcn/zvac072.Peer-Reviewed Original ResearchConceptsSleep-related cognitionsCognitive behavioral therapySleep characteristicsPandemic-related stressPandemic-related stressorsSymptoms of anxietyInvoluntary engagementInvoluntary disengagementBehavioral therapyStressful eventsSleep problemsInsomnia severityMood disturbanceCopingCOVID-19 pandemicSecondary controlAnxietyCognitionParticipantsDaytime symptomsHeart failureInsomniaDepressionPeopleCBTSleep Characteristics, Mood, Somatic Symptoms, and Self-Care Among People With Heart Failure and Insomnia
Breazeale S, Jeon S, Hwang Y, O’Connell M, Nwanaji-Enwerem U, Linsky S, Yaggi HK, Jacoby DL, Conley S, Redeker NS. Sleep Characteristics, Mood, Somatic Symptoms, and Self-Care Among People With Heart Failure and Insomnia. Nursing Research 2022, 71: 189-199. PMID: 35149627, PMCID: PMC9038676, DOI: 10.1097/nnr.0000000000000585.Peer-Reviewed Original ResearchConceptsSelf-care maintenanceStable heart failureSelf-care confidenceVentricular ejection fractionHeart failureChronic insomniaSleep characteristicsSomatic symptomsClinical factorsEjection fractionLeft ventricular ejection fractionChronic heart failureSelf-care behaviorsPoor sleep characteristicsSymptoms of anxietyCross-sectional designSleep disturbancesSingle symptomWhite raceHigh riskCombined associationsInsomnia severityInsomniaSymptomsHealthcare needsSleep, Stress, and Symptoms Among People With Heart Failure During the COVID-19 Pandemic
O'Connell M, Jeon S, Conley S, Linsky S, Redeker NS. Sleep, Stress, and Symptoms Among People With Heart Failure During the COVID-19 Pandemic. The Journal Of Cardiovascular Nursing 2022, 38: e55-e60. PMID: 35324509, PMCID: PMC9508278, DOI: 10.1097/jcn.0000000000000906.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapySleep-related cognitionsHeart failureSelf-reported sleep characteristicsStressful eventsEffects of stressCOVID-19 pandemicMental healthMonths post treatmentSelf-management educationSleep characteristicsMoodSleepChronic conditionsInsomniaSymptomsTherapyPeopleCognitionCopingPost treatmentAnxietyPandemicSignificant improvement
2020
Day-to-day Relationships between Physical Activity and Sleep Characteristics among People with Heart Failure and Insomnia
Ash G, Jeon S, Conley S, Knies AK, Yaggi HK, Jacoby D, Hollenbeak CS, Linsky S, O’Connell M, Redeker NS. Day-to-day Relationships between Physical Activity and Sleep Characteristics among People with Heart Failure and Insomnia. Behavioral Sleep Medicine 2020, 19: 602-614. PMID: 33048589, PMCID: PMC8496686, DOI: 10.1080/15402002.2020.1824918.Peer-Reviewed Original ResearchConceptsNext-day physical activityHeart failureTotal sleep timePhysical activityCounts/minuteSleep characteristicsSleep timeSleep variablesNYHA class IIAdvanced heart failureStable heart failureDaytime physical activityBody mass indexCommunity-dwelling adultsWrist actigraphy recordingsCognitive behavioral therapyNYHA classHF classMass indexSleep improvementActigraphy recordingsLong sleepBehavioral therapyClass IIInsomniaEmpagliflozin in Heart Failure
Griffin M, Rao VS, Ivey-Miranda J, Fleming J, Mahoney D, Maulion C, Suda N, Siwakoti K, Ahmad T, Jacoby D, Riello R, Bellumkonda L, Cox Z, Collins S, Jeon S, Turner JM, Wilson FP, Butler J, Inzucchi SE, Testani JM. Empagliflozin in Heart Failure. Circulation 2020, 142: 1028-1039. PMID: 32410463, PMCID: PMC7521417, DOI: 10.1161/circulationaha.120.045691.Peer-Reviewed Original ResearchConceptsSodium-glucose cotransporter 2 inhibitorsCotransporter 2 inhibitorsNeurohormonal activationHeart failureRenal dysfunctionBlood volumeHeart failure-related outcomesPlacebo-controlled crossover studyType 2 diabetes mellitusProximal tubular siteHeart failure outcomesStable heart failureUrinary glucose excretionUric acid levelsElectrolyte wastingEmpagliflozin monotherapyOral empagliflozinPlacebo periodStudy drugGlucose excretionNatriuretic effectPotassium wastingTubular sitesDiabetes mellitusFractional excretionPerceived Stress, Subjective, and Objective Symptoms of Disturbed Sleep in Men and Women with Stable Heart Failure
Gaffey AE, Jeon S, Conley S, Jacoby D, Ash GI, Yaggi HK, O’Connell M, Linsky SJ, Redeker NS. Perceived Stress, Subjective, and Objective Symptoms of Disturbed Sleep in Men and Women with Stable Heart Failure. Behavioral Sleep Medicine 2020, 19: 363-377. PMID: 32394733, PMCID: PMC7658015, DOI: 10.1080/15402002.2020.1762601.Peer-Reviewed Original ResearchMeSH KeywordsAgedFemaleHeart FailureHumansMaleMiddle AgedSleep Initiation and Maintenance DisordersStress, PsychologicalConceptsDysfunctional beliefsCognitive abilitiesMental healthCognitive behavioral therapySymptom severitySleep disturbance questionnaireSleep disturbancesHF patientsSelf-reported sleep disturbanceHeart failurePerceived Stress ScaleBehavioral therapyInsomnia Severity IndexPerceived stressStress ScaleBaseline stressPittsburgh Sleep Quality IndexDisturbance QuestionnaireLower symptomsSleep Quality IndexNew York Heart Association classification ISF-36 mental healthSleep-related characteristicsStable heart failureSleep ScaleReal World Use of Hypertonic Saline in Refractory Acute Decompensated Heart Failure A U.S. Center’s Experience
Griffin M, Soufer A, Goljo E, Colna M, Rao VS, Jeon S, Raghavendra P, D'Ambrosi J, Riello R, Coca SG, Mahoney D, Jacoby D, Ahmad T, Chen M, Tang WHW, Turner J, Mullens W, Wilson FP, Testani JM. Real World Use of Hypertonic Saline in Refractory Acute Decompensated Heart Failure A U.S. Center’s Experience. JACC Heart Failure 2020, 8: 199-208. PMID: 32035891, PMCID: PMC7814403, DOI: 10.1016/j.jchf.2019.10.012.Peer-Reviewed Original ResearchConceptsAcute decompensated heart failureHypertonic saline administrationHypertonic saline therapyHypertonic salineSaline administrationSaline therapyDiuretic efficiencyUrine outputSerum sodiumWeight lossAcute decompensated heartDecompensated heart failureCohort of patientsTotal urine outputReal-world safetyU.S. academic medical centersAcademic medical centerLarge U.S. academic medical centerDiuretic doseCenter experienceHeart failureMetabolic derangementsPrimary analytic approachRespiratory statusClinical variables
2019
Daytime and Nighttime Sleep Characteristics and Pain Among Adults With Stable Heart Failure.
Conley S, Feder SL, Jeon S, Redeker NS. Daytime and Nighttime Sleep Characteristics and Pain Among Adults With Stable Heart Failure. The Journal Of Cardiovascular Nursing 2019, 34: 390-398. PMID: 31365442, PMCID: PMC6690780, DOI: 10.1097/jcn.0000000000000593.Peer-Reviewed Original ResearchConceptsPoor sleep qualityHeart failureSleep medicationSleep characteristicsDaytime sleepinessSleep qualitySleep durationSelf-reported poor sleep qualityPittsburgh Sleep Quality IndexMore sleep medicationsStable heart failureBodily pain scaleSleep Quality IndexCross-sectional studyPresence of insomniaLong sleep durationNighttime sleep characteristicsSpecific sleep characteristicsSleep Habits QuestionnaireNocturnal sleep characteristicsPain scaleSymptom burdenMore painSleep disturbancesInsomnia symptoms
2018
Effects of Cognitive Behavioral Therapy for Insomnia on Sleep, Symptoms, Stress, and Autonomic Function Among Patients With Heart Failure
Redeker NS, Conley S, Anderson G, Cline J, Andrews L, Mohsenin V, Jacoby D, Jeon S. Effects of Cognitive Behavioral Therapy for Insomnia on Sleep, Symptoms, Stress, and Autonomic Function Among Patients With Heart Failure. Behavioral Sleep Medicine 2018, 18: 190-202. PMID: 30461315, PMCID: PMC6529289, DOI: 10.1080/15402002.2018.1546709.Peer-Reviewed Original ResearchConceptsUrinary free cortisolHeart failureAutonomic functionCognitive behavioral therapyFree cortisolSleep characteristicsSleep-related cognitionsBehavioral therapyChronic heart failureStable heart failureSleep-related symptomsHypothalamic-pituitary axisStable class IISelf-reported insomnia severityEffects of CBTFunctional performanceDaytime symptomsPituitary axisSleep disturbancesSleep interventionsWrist actigraphySleep durationInsomnia severityBiomarkers of stressRatio of days