The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes
Knobf MT, Jeon S, Smith B, Harris L, Thompson S, Stacy MR, Insogna K, Sinusas AJ. The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes. Heart & Lung 2017, 46: 375-381. PMID: 28803675, PMCID: PMC6129386, DOI: 10.1016/j.hrtlng.2017.06.001.Peer-Reviewed Original ResearchConceptsFemale cancer survivorsCancer survivorsCenter interventionMET-minutes/weekStable insulin levelsMetabolic risk factorsResistance exercise programExercise stress testCardiovascular disease riskPhysical activity groupImproved insulin resistanceHeart rate recoveryMinutes/weekRisk reduction interventionsMajority of subjectsAdjuvant chemotherapyPremature menopauseExercise programInsulin levelsInsulin resistanceIntervention trialsRisk factorsCardiovascular functionBreast cancerRate recoveryExercise, metabolic syndrome, and cardiovascular fitness in breast cancer survivors.
Knobf M, Sinusas A, Holland M, Jeon S. Exercise, metabolic syndrome, and cardiovascular fitness in breast cancer survivors. Journal Of Clinical Oncology 2017, 35: 165-165. DOI: 10.1200/jco.2017.35.5_suppl.165.Peer-Reviewed Original ResearchBreast cancer survivorsPhysical activity groupHeart rate recoveryMetabolic syndromeCancer survivorsLifestyle behaviorsCardiovascular diseaseRate recoveryCardiovascular fitnessAge-matched postmenopausal womenBreast cancer-specific mortalityActivity groupHigh baseline incidenceCancer-specific mortalityFirst-line interventionCause mortalityEndocrine therapyPostmenopausal womenExercise interventionMetS componentsMetS criteriaDiastolic BPSystolic BPMonths interventionMetabolic outcomes