2017
Exercise, metabolic syndrome, and cardiovascular fitness in breast cancer survivors.
Knobf M, Sinusas A, Holland M, Jeon S. Exercise, metabolic syndrome, and cardiovascular fitness in breast cancer survivors. Journal Of Clinical Oncology 2017, 35: 165-165. DOI: 10.1200/jco.2017.35.5_suppl.165.Peer-Reviewed Original ResearchBreast cancer survivorsPhysical activity groupHeart rate recoveryMetabolic syndromeCancer survivorsLifestyle behaviorsCardiovascular diseaseRate recoveryCardiovascular fitnessAge-matched postmenopausal womenBreast cancer-specific mortalityActivity groupHigh baseline incidenceCancer-specific mortalityFirst-line interventionCause mortalityEndocrine therapyPostmenopausal womenExercise interventionMetS componentsMetS criteriaDiastolic BPSystolic BPMonths interventionMetabolic outcomes
2016
Effect of a randomized controlled exercise trial on bone outcomes: influence of adjuvant endocrine therapy
Knobf MT, Jeon S, Smith B, Harris L, Kerstetter J, Thompson AS, Insogna K. Effect of a randomized controlled exercise trial on bone outcomes: influence of adjuvant endocrine therapy. Breast Cancer Research And Treatment 2016, 155: 491-500. PMID: 26850265, DOI: 10.1007/s10549-016-3693-3.Peer-Reviewed Original ResearchConceptsFemale cancer survivorsPhysical activity groupEndocrine therapyBone outcomesExercise interventionBone lossFemoral neckAromatase inhibitorsActivity groupAdjuvant AI therapyChemotherapy-induced menopauseSufficient serum levelsAdjuvant endocrine therapyVitamin D supplementsHealthy postmenopausal womenLess bone lossHome-based groupSignificant BMD lossSignificant clinical problemMajority of subjectsAI therapyD supplementsPostmenopausal womenBMD lossBMD outcomes