2020
Treatment Selection and Survival Outcomes in Locally Advanced Proximal Gastric Cancer: A National Cancer Data Base Analysis
Tang S, Liu F, Li Y, Zhao L, Wang X, Khan SA, Chen Y, Zhang Y. Treatment Selection and Survival Outcomes in Locally Advanced Proximal Gastric Cancer: A National Cancer Data Base Analysis. Frontiers In Oncology 2020, 10: 537051. PMID: 33102212, PMCID: PMC7546198, DOI: 10.3389/fonc.2020.537051.Peer-Reviewed Original ResearchBetter long-term outcomesProximal gastrectomyTotal gastrectomyLong-term outcomesPreoperative chemotherapyAdvanced proximal gastric cancer patientsNational Cancer Data Base analysisAdvanced proximal gastric cancerProximal gastric cancer patientsNational Cancer Data BaseCox proportional hazards modelPostoperative chemoradiation therapyProximal gastric cancerUnderwent proximal gastrectomyUnderwent total gastrectomyImproved overall survivalProximal gastric adenocarcinomaGastric cancer patientsProportional hazards modelLong-term survivalEligible patientsPostoperative chemotherapyAdjuvant therapyChemoradiation therapyMultimodality treatment
2018
Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum
Zhu R, Liu F, Grisotti G, Pérez-Irizarry J, Cha CH, Johnson CH, Boffa DJ, Han D, Johung KL, Zhang Y, Khan SA. Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum. Journal Of Gastrointestinal Oncology 2018, 9: 231-240. PMID: 29755761, PMCID: PMC5934147, DOI: 10.21037/jgo.2017.11.12.Peer-Reviewed Original ResearchRectal gastrointestinal stromal tumorGastric gastrointestinal stromal tumorsGastrointestinal stromal tumorsNational Cancer Data BaseAdjuvant therapyOverall survivalSystemic therapyStromal tumorsCases of GISTColonic gastrointestinal stromal tumorsSmall bowel originAdjuvant systemic therapyWorse overall survivalUnique clinicopathologic featuresBowel originTherapy prolongsClinical characteristicsPatient demographicsLocal excisionPrognostic factorsPropensity matchingSurgical treatmentTreatment guidelinesClinicopathologic featuresClinical care
2017
Post-operative radiotherapy is associated with improved survival in esophageal cancer with positive surgical margins
Gao SJ, Park HS, Corso CD, Rutter CE, Khan SA, Johung KL. Post-operative radiotherapy is associated with improved survival in esophageal cancer with positive surgical margins. Journal Of Gastrointestinal Oncology 2017, 8: 953-961. PMID: 29299354, PMCID: PMC5750177, DOI: 10.21037/jgo.2017.08.12.Peer-Reviewed Original ResearchPost-operative radiotherapyClinical stage INational Cancer Data BaseEarly-stage esophageal cancerOverall survivalPositive surgical marginsPositive marginsUpfront esophagectomyEsophageal cancerStage IImproved survivalSurgical marginsMultivariable Cox regression analysisImproved overall survivalReceipt of chemotherapyCox regression analysisMultivariable logistic regressionEsophageal cancer patientsLog-rank testAdjuvant chemotherapyOS benefitPostoperative chemotherapyPN0 diseaseMultivariable analysisCancer patientsPredictors of Nonadherence to NCCN Guideline Recommendations for the Management of Stage I Anal Canal Cancer.
Kole AJ, Stahl JM, Park HS, Khan SA, Johung KL. Predictors of Nonadherence to NCCN Guideline Recommendations for the Management of Stage I Anal Canal Cancer. Journal Of The National Comprehensive Cancer Network 2017, 15: 355-362. PMID: 28275036, DOI: 10.6004/jnccn.2017.0035.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsAnus NeoplasmsCombined Modality TherapyDatabases, FactualDisease ManagementFemaleHumansMaleMedication AdherenceMiddle AgedNeoplasm GradingNeoplasm StagingOdds RatioPractice Guidelines as TopicPrognosisProportional Hazards ModelsRisk FactorsTreatment OutcomeConceptsAnal canal cancerAnal cancerNCCN recommendationsSurgical proceduresNCCN Clinical Practice GuidelinesNational Cancer Data BaseGuideline-discordant careAnal canal carcinomaPredictors of nonadherenceClinical practice guidelinesHigh tumor gradeLow-grade tumorsLogistic regression modelingNon-academic facilitiesChi-square testDefinitive chemoradiotherapyGuideline concordantConcurrent chemoradiotherapyAnal carcinomaStandard therapyClinicopathologic factorsGuideline recommendationsMultivariable analysisMale sexTumor size