2023
Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas.
Tabor J, O'Brien J, Vasandani S, Vetsa S, Lei H, Jalal M, Marianayagam N, Jin L, Millares Chavez M, Haynes J, Dincer A, Yalcin K, Aguilera S, Omay S, Mishra-Gorur K, McGuone D, Morales-Valero S, Fulbright R, Gunel M, Erson-Omay E, Moliterno J. Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas. Journal Of Neurosurgery 2023, 139: 1648-1656. PMID: 37243548, DOI: 10.3171/2023.4.jns222929.Peer-Reviewed Original ResearchConceptsSubtotal resectionSupratentorial tumorsElevated Ki-67High-risk featuresProgression-free survivalChromosome 1p deletionInfratentorial counterpartsInfratentorial tumorsPostoperative managementSomatic driver mutationsCerebral convexityGrade IIInfratentorial meningiomasKi-67Posterior fossaLoss of heterozygosityMeningiomasResectionTumorsWhole-exome sequencing dataDriver mutationsHigh gradeSignificant differencesExome sequencing dataSporadic meningiomas
2017
Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas?
Omay SB, Almeida JP, Chen YN, Shetty SR, Liang B, Ni S, Anand VK, Schwartz TH. Is the chiasm-pituitary corridor size important for achieving gross-total resection during endonasal endoscopic resection of craniopharyngiomas? Journal Of Neurosurgery 2017, 129: 642-647. PMID: 29171802, DOI: 10.3171/2017.6.jns163188.Peer-Reviewed Original ResearchConceptsGross total resectionExtended endonasal approachSubtotal resectionLarge tumorsPituitary glandFirst-line surgical approachEndonasal endoscopic resectionAvailable preoperative imagingMidline craniopharyngiomasOBJECTIVE CraniopharyngiomasPrefixed chiasmEndocrine outcomesRelative contraindicationVisual outcomeEndoscopic resectionAuthors' centerPreoperative imagingOptic chiasmSurgical approachVisual deteriorationResults ThirtyPituitary stalkThird ventricleHigh riskResection