2020
In-Depth Analysis of Genetic Variation Associated with Severe West Nile Viral Disease
Cahill ME, Loeb M, Dewan AT, Montgomery RR. In-Depth Analysis of Genetic Variation Associated with Severe West Nile Viral Disease. Vaccines 2020, 8: 744. PMID: 33302579, PMCID: PMC7768385, DOI: 10.3390/vaccines8040744.Peer-Reviewed Original ResearchAdditional novel variantsWest Nile virusNovel genetic variantsComprehensive genetic studiesGenetic Variation AssociatedGenetic architectureGene-gene interaction analysisNovel lociGene targetsLocus analysisBiological roleGenetic studiesGenetic variantsVirus datasetCell linesVariation AssociatedSevere West Nile neuroinvasive diseaseNovel variantsMosquito-borne virusViable targetViral diseasesNile virusInteraction analysisGenesLoci
2018
Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis
Cahill ME, Conley S, DeWan AT, Montgomery RR. Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis. BMC Infectious Diseases 2018, 18: 282. PMID: 29929468, PMCID: PMC6014009, DOI: 10.1186/s12879-018-3186-6.Peer-Reviewed Original ResearchConceptsWest Nile virus diseaseSevere diseaseVirus diseaseWest Nile virus infectionGenetic factorsGenetic variantsSevere disease outcomesPotential therapeutic interventionsGenetic risk factorsAdditional genetic factorsWest Nile virusMinority of individualsSymptomatic infectionAsymptomatic infectionMechanisms of resistanceRisk factorsImmune mechanismsInitial symptomsDisease outcomeVirus infectionImmune responseDengue diseaseDisease pathogenesisTherapeutic interventionsSystematic review