2008
Human Babesiosis
Vannier E, Gewurz BE, Krause PJ. Human Babesiosis. Infectious Disease Clinics Of North America 2008, 22: 469-488. PMID: 18755385, PMCID: PMC3998201, DOI: 10.1016/j.idc.2008.03.010.Peer-Reviewed Original ResearchConceptsBabesial infectionHuman babesiosisCombination of atovaquoneTreatment of choiceSpecific laboratory diagnosisModerate illnessExchange transfusionPolymerase chain reactionSevere diseaseLaboratory diagnosisMorphologic examinationBlood smearsProtozoal parasitesInfectionChain reactionBabesial DNABabesiosisIntraerythrocytic infectionUnited StatesIxodid ticksTransfusionUpper midwestern regionsClindamycinSerologyAzithromycinPersistent and Relapsing Babesiosis in Immunocompromised Patients
Krause PJ, Gewurz BE, Hill D, Marty FM, Vannier E, Foppa IM, Furman RR, Neuhaus E, Skowron G, Gupta S, McCalla C, Pesanti EL, Young M, Heiman D, Hsue G, Gelfand JA, Wormser GP, Dickason J, Bia FJ, Hartman B, Telford SR, Christianson D, Dardick K, Coleman M, Girotto JE, Spielman A. Persistent and Relapsing Babesiosis in Immunocompromised Patients. Clinical Infectious Diseases 2008, 46: 370-376. PMID: 18181735, DOI: 10.1086/525852.Peer-Reviewed Original ResearchConceptsCase patientsAntibabesial treatmentClinical courseControl subjectsBlood smearsRetrospective case-control studyOptimal treatment regimenStandard antimicrobial therapyMalaria-like illnessBabesia microti infectionMost cases patientsCase-control studyCourse of therapyB-cell lymphomaAdministration of atovaquoneImmunologic statusStandard therapyAntimicrobial regimenSuch patientsTreatment regimenMicroti infectionAntimicrobial therapyPersistent infectionCell lymphomaAcute babesiosis
2002
Disease-Specific Diagnosis of Coinfecting Tickborne Zoonoses: Babesiosis, Human Granulocytic Ehrlichiosis, and Lyme Disease
Krause PJ, McKay K, Thompson CA, Sikand VK, Lentz R, Lepore T, Closter L, Christianson D, Telford SR, Persing D, Radolf JD, Spielman A, Group A. Disease-Specific Diagnosis of Coinfecting Tickborne Zoonoses: Babesiosis, Human Granulocytic Ehrlichiosis, and Lyme Disease. Clinical Infectious Diseases 2002, 34: 1184-1191. PMID: 11941544, DOI: 10.1086/339813.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisLyme diseaseImmunoglobulin M antibody testGranulocytic ehrlichiosisPolymerase chain reaction testingShort-term complicationsComplete blood countDisease-specific diagnosisFlulike illnessThin blood smearsLaboratory manifestationsAcute manifestationsBlood countBlood samplesAntibody testReaction testingBlood smearsTickborne zoonosesDiseaseHuman babesiosisLaboratory test resultsPatientsStructured questionnaireSymptomsBabesiosis
2001
Coinfecting Deer-Associated Zoonoses: Lyme Disease, Babesiosis, and Ehrlichiosis
Goldstein E, Thompson C, Spielman A, Krause P. Coinfecting Deer-Associated Zoonoses: Lyme Disease, Babesiosis, and Ehrlichiosis. Clinical Infectious Diseases 2001, 33: 676-685. PMID: 11486290, DOI: 10.1086/322681.Peer-Reviewed Original ResearchConceptsLyme diseaseDuration of symptomsHuman granulocytic ehrlichiosisTickborne infectionClinical managementHealth burdenHuman coinfectionsDiagnostic proceduresGranulocytic ehrlichiosisDisease syndromeHuman babesiosisRodent reservoirsHuman hostInfectionDiseaseEhrlichiosisDiversity of pathogensBabesiosisPathogensCoinfectionSyndromeSymptomsIncidenceVector host