2021
Babesiosis
Chen T, Mamoun C, Krause P. Babesiosis. 2021, 1298-1304. DOI: 10.1093/med/9780190888367.003.0200.Peer-Reviewed Original ResearchB. microtiHard-bodied ticksHuman granulocytic anaplasmosisPowassan virusEtiologic agentIntraerythrocytic protozoaLyme diseaseBorrelia miyamotoiGranulocytic anaplasmosisBabesia infectionBorrelia burgdorferiDiseaseZoonotic diseaseB. duncaniAnaplasma phagocytophilumApicomplexa phylumInfectionMicrotiB. venatorumB. divergensBabesia sppBabesiosisIxodes scapularisPrimary vectorFever
2015
Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences
Diuk-Wasser MA, Vannier E, Krause PJ. Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences. Trends In Parasitology 2015, 32: 30-42. PMID: 26613664, PMCID: PMC4713283, DOI: 10.1016/j.pt.2015.09.008.Peer-Reviewed Original ResearchConceptsB. microtiDisease severityGreater disease severityEnzootic cycleCoinfected individualsTick-borne pathogenClinical consequencesTherapeutic strategiesLyme diseaseBabesia microtiHost factorsCoinfectionBorrelia burgdorferiB. burgdorferiIxodes ticksMicrotiReservoir hostsSeverityHuman pathogensBurgdorferi
2010
Emergence of Resistance to Azithromycin-Atovaquone in Immunocompromised Patients with Babesia microti Infection
Wormser GP, Prasad A, Neuhaus E, Joshi S, Nowakowski J, Nelson J, Mittleman A, Aguero-Rosenfeld M, Topal J, Krause PJ. Emergence of Resistance to Azithromycin-Atovaquone in Immunocompromised Patients with Babesia microti Infection. Clinical Infectious Diseases 2010, 50: 381-386. PMID: 20047477, DOI: 10.1086/649859.Peer-Reviewed Original ResearchConceptsDrug regimenB. microtiLevel of immunosuppressionBabesia microti infectionTreatment of babesiosisDrug-resistant strainsEmergence of resistanceActive babesiosisMicrobiologic relapseLaboratory abnormalitiesDrug regimensImmunocompromised patientsOptimal therapyTreatment failureDrug therapyMicroti infectionPatientsClinical case historiesDrug resistanceBabesia microtiInfectionRegimenMicrotiEventual developmentBabesiosis
2000
Serological Expression Cloning of Novel Immunoreactive Antigens of Babesia microti
Lodes M, Houghton R, Bruinsma E, Mohamath R, Reynolds L, Benson D, Krause P, Reed S, Persing D. Serological Expression Cloning of Novel Immunoreactive Antigens of Babesia microti. Infection And Immunity 2000, 68: 2783-2790. PMID: 10768973, PMCID: PMC97488, DOI: 10.1128/iai.68.5.2783-2790.2000.Peer-Reviewed Original ResearchConceptsRelated antigensBabesia microtiSerological expression cloningB. microtiHumoral immune responseB. microti infectionClass of antigensSporozoite surface antigenPatient serum poolsWestern blot analysisBlood transfusionMicroti infectionImmune responseSurface antigenImmunodominant antigensAntigenHuman babesiosisMolecular testsGenomic expression libraryPlasmodium spCausative agentSerum poolsImmunoreactive antigensBlot analysisMicroti