2002
Notch Signaling in the Brain: More than Just a Developmental Story
Šestan N, Rakic P. Notch Signaling in the Brain: More than Just a Developmental Story. Research And Perspectives In Alzheimer's Disease 2002, 19-40. DOI: 10.1007/978-3-642-55996-9_2.Peer-Reviewed Original ResearchNotch signalingNeural developmentCell-cell interaction mechanismCell fate acquisitionCell fate decisionsEarly neural developmentDifferent signaling mechanismsVariety of speciesFate acquisitionNotch signalsCellular phenotypesNotch pathwayMolecular mechanismsSignaling mechanismApoptotic cuesNeuronal differentiationMolecular processesNervous systemAlzheimer's diseaseAdult-onset neurological disordersNeural cellsImportant playersSignalingNeurodegenerative disordersLife span
1999
Contact-Dependent Inhibition of Cortical Neurite Growth Mediated by Notch Signaling
Šestan N, Artavanis-Tsakonas S, Rakic P. Contact-Dependent Inhibition of Cortical Neurite Growth Mediated by Notch Signaling. Science 1999, 286: 741-746. PMID: 10531053, DOI: 10.1126/science.286.5440.741.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell CommunicationCell CountCell DifferentiationCell MovementCell NucleusCell SizeCells, CulturedCerebral CortexContact InhibitionHumansLigandsMembrane ProteinsMiceMitosisNeuritesNeuronsProtein Structure, TertiaryReceptor, Notch1Receptor, Notch2Receptors, Cell SurfaceSignal TransductionTranscription FactorsTranscriptional ActivationUp-RegulationConceptsNeurite growthMouse cerebral cortexCapacity of neuronsCortical neurite growthStudy of neuronsInhibition of NotchCerebral cortexNotch signalingCortical neuronsNotch activityMature neuronsInterneuronal contactsRetraction of neuritesHigh Notch activityNeuronsNeuronal growthNeuritesContact-dependent inhibitionExuberant growthNeurite extensionNotch receptorsInhibitionLow Notch activitySignalingActivity