1992
Immunocytochemical localization of DARPP‐32, a dopamine and cyclic‐ AMP‐regulated phosphoprotein, in the primate brain
Ouimet C, Lamantia A, Goldman‐Rakic P, Rakic P, Greengard P. Immunocytochemical localization of DARPP‐32, a dopamine and cyclic‐ AMP‐regulated phosphoprotein, in the primate brain. The Journal Of Comparative Neurology 1992, 323: 209-218. PMID: 1328330, DOI: 10.1002/cne.903230206.Peer-Reviewed Original ResearchConceptsDARPP-32Axon terminalsCaudate nucleusDARPP-32-positive neuronsSubstantia nigra pars reticulataAnterior olfactory areaMajority of somataSubcortical white matterUnlabeled axon terminalsAction of dopamineVentral tegmental areaDARPP-32 immunoreactivityCerebral cortexPars reticulataDopaminergic neuronsImmunoreactive somataSubstantia nigraArcuate nucleusGlobus pallidusTegmental areaMedial habenulaDopamine receptorsOlfactory areasVentral pallidumBed nucleus
1989
Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride.
Lidow M, Goldman-Rakic P, Rakic P, Innis R. Dopamine D2 receptors in the cerebral cortex: distribution and pharmacological characterization with [3H]raclopride. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 6412-6416. PMID: 2548214, PMCID: PMC297850, DOI: 10.1073/pnas.86.16.6412.Peer-Reviewed Original ResearchConceptsDopamine D2 receptorsD2 receptorsD2 sitesDopamine D1 receptorsNeostriatum of ratsD2-selective antagonistRostral-caudal gradientCerebral cortexDopaminergic innervationD1 receptorsDopamine levelsDopamine receptorsPharmacological characterizationRat cortexSelective antagonistOccipital cortexPharmacological profileCognitive functionCortexReceptorsNeostriatumApparent involvementPresent studySaturable mannerMonkeys