2024
Safety and Efficacy of a Composite Lipid Emulsion with Fish Oil in Hospitalized Neonates and Infants Requiring Prolonged Parenteral Nutrition - A Randomized, Double-Blind, Multicenter, Controlled Trial
Abrams S, Ernst K, Weitkamp J, Mascarenhas M, Anderson-Berry A, Rudolph J, Ling C, Robinson D, Shores D, Hair A, Lai J, Lane B, McCallie K, Levit O, Kim J. Safety and Efficacy of a Composite Lipid Emulsion with Fish Oil in Hospitalized Neonates and Infants Requiring Prolonged Parenteral Nutrition - A Randomized, Double-Blind, Multicenter, Controlled Trial. Journal Of Nutrition 2024 PMID: 39374788, DOI: 10.1016/j.tjnut.2024.10.005.Peer-Reviewed Original ResearchSoybean oil lipid emulsionsInitial treatment phaseHigh-risk neonatesParenteral nutritionTreatment phaseLipid emulsionDouble-blindEfficacy of parenteral nutritionEvidence of essential fatty acid deficiencyComposite lipid emulsionProlonged parenteral nutritionRisk of cholestasisEssential fatty acid deficiencyHigh-risk infantsIntravenous lipid emulsionFatty acid deficiencyExtended treatment phaseIntravenous lipidsHospitalized neonatesConjugated bilirubin concentrationsMedian timeGastrointestinal malformationsMulticenter studyLaboratory evidencePrimary outcome
2015
Is a haptic simulation interface more effective than computer mouse-based interface for neonatal intubation skills training?
Anup Agarwal, Julie Leviter, Candace Mannarino, Orly Levit, Lindsay Johnston, Marc Auerbach. BMJ STEL 2015;1:5-11 Published Online First: 7 May 2015 doi:10.1136/bmjstel-2015-000016Peer-Reviewed Original ResearchDo you see what I see? A randomised pilot study to evaluate the effectiveness and efficiency of simulation-based training with videolaryngoscopy for neonatal intubation
Lindsay C Johnston, Ruijun Chen, Travis M Whitfill, Christie J Bruno, Orly L Levit, Marc A Auerbach. BMJ STEL 2015;1:12-18 Published Online First: 20 May 2015 doi:10.1136/bmjstel-2015-000031Peer-Reviewed Original Research
2014
Systematic use of the RAM nasal cannula in the Yale–New Haven Children’s Hospital Neonatal Intensive Care Unit: a quality improvement project
Nzegwu NI, Mack T, DellaVentura R, Dunphy L, Koval N, Levit O, Bhandari V. Systematic use of the RAM nasal cannula in the Yale–New Haven Children’s Hospital Neonatal Intensive Care Unit: a quality improvement project. The Journal Of Maternal-Fetal & Neonatal Medicine 2014, 28: 718-721. PMID: 24874561, DOI: 10.3109/14767058.2014.929659.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitNon-invasive ventilationNasal continuous positive airway pressure ventilationNasal intermittent positive pressure ventilationHospital Neonatal Intensive Care UnitNasal cannulaIntensive care unitCare unitPressure ventilationChildren's Hospital neonatal intensive care unitContinuous positive airway pressure ventilationPositive airway pressure ventilationIntermittent positive pressure ventilationPositive pressure ventilationQuality improvement projectOverall success rateNIPPV groupRespiratory supportNeonatal populationSingle centerClinical efficacySmall trialsObservational studyStatement recommendationsInfantsLow‐Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates
Levit OL, Calkins KL, Gibson LC, Kelley‐Quon L, Robinson DT, Elashoff DA, Grogan TR, Li N, Bizzarro MJ, Ehrenkranz RA. Low‐Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates. Journal Of Parenteral And Enteral Nutrition 2014, 40: 374-382. PMID: 24963025, PMCID: PMC4537394, DOI: 10.1177/0148607114540005.Peer-Reviewed Original ResearchConceptsDays of lifeIntravenous fat emulsionPreterm neonatesPrimary outcomeGestational ageControl groupControl doseFat emulsionDays of PNFull enteral feedsPrevention of cholestasisMajor neonatal morbidityHours of lifeEffective preventive strategiesLow groupHospital stayNeonatal morbidityBaseline characteristicsParenteral nutritionSecondary outcomesEnteral feedsEssential fatty acidsPremature infantsLiver diseaseTotal bilirubinClinical and Laboratory Factors That Predict Death in Very Low Birth Weight Infants Presenting With Late-onset Sepsis
Levit O, Bhandari V, Li FY, Shabanova V, Gallagher PG, Bizzarro MJ. Clinical and Laboratory Factors That Predict Death in Very Low Birth Weight Infants Presenting With Late-onset Sepsis. The Pediatric Infectious Disease Journal 2014, 33: 143-146. PMID: 24418836, PMCID: PMC3917323, DOI: 10.1097/inf.0000000000000024.Peer-Reviewed Original ResearchConceptsLate-onset sepsisLow birth weight infantsBirth weight infantsIndependent risk factorLaboratory factorsWeight infantsVLBW infantsRisk factorsCases of LOSEpisodes of LOSRisk of LOSFungal LOSNeonatal intensive care unitMultivariate logistic regression analysisSepsis-related deathsIntensive care unitOnset of illnessSepsis-associated mortalityGram-positive infectionsLogistic regression analysisOnset of diseasePresentation of illnessComposite risk profileLaboratory signsNecrotizing enterocolitis