2022
Anticoagulation strategies and recurrence of venous thromboembolic events in patients with sickle cell disease: a systematic review and meta-analysis
El-Amin N, Iness A, Cyrus JW, Sisler I, Karam O. Anticoagulation strategies and recurrence of venous thromboembolic events in patients with sickle cell disease: a systematic review and meta-analysis. Annals Of Hematology 2022, 101: 1931-1940. PMID: 35895101, DOI: 10.1007/s00277-022-04901-z.Peer-Reviewed Original ResearchConceptsVenous thromboembolic eventsSickle cell diseaseCell diseaseThromboembolic eventsPulmonary embolismSystematic reviewDevelopment of bleedingOverall bleeding rateVenous thrombotic eventsRisk of mortalityProgression of thrombusAnticoagulant classDifferent anticoagulationAnticoagulation strategiesOverall recurrenceOverall mortalityThrombotic eventsAdverse outcomesPatient populationBleeding rateObservational studyOutcome measuresAppropriate managementPatientsRecurrence
2021
Epidemiology of Bleeding in Critically Ill Children
Sequeira J, Nellis ME, Karam O. Epidemiology of Bleeding in Critically Ill Children. Frontiers In Pediatrics 2021, 9: 699991. PMID: 34422724, PMCID: PMC8371326, DOI: 10.3389/fped.2021.699991.Peer-Reviewed Original ResearchPediatric critical care unitRisk of mortalityCritical care unitsIll childrenCare unitClinical outcomesProspective observational cohort studyEpidemiology of BleedingPICU-free daysPercent of patientsVentilator-free daysDuration of surgeryObservational cohort studyCritically Ill ChildrenWorse clinical outcomesType of surgeryFurther multicenter studiesHigher severityCohort studyCritical illnessPediatric IndexSevere complicationsConsecutive patientsIll patientsMedian age