2019
Development of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections.
Shein SL, Karam O, Beardsley A, Karsies T, Prentice E, Tarquinio KM, Willson DF. Development of an Antibiotic Guideline for Children With Suspected Ventilator-Associated Infections. Pediatric Critical Care Medicine 2019, 20: 697-706. PMID: 30985606, DOI: 10.1097/pcc.0000000000001942.Peer-Reviewed Original ResearchConceptsVentilator-associated infectionPhase 1 dataAntibiotic guidelinesGuideline scoreAntibiotic usePediatric Logistic Organ Dysfunction-2 scoreDuration of antibioticsPICU-free daysVentilator-Associated InfectionsVentilator-free daysInitiation of antibioticsProspective data collectionPhase 3Median ageMechanical ventilationVentilated childrenScore 3Consensus conferenceClinical testingScoring systemInfectionLiterature searchExpert panelAntibioticsScores
2016
Performance of the PEdiatric Logistic Organ Dysfunction-2 score in critically ill children requiring plasma transfusions
Karam O, Demaret P, Duhamel A, Shefler A, Spinella PC, Stanworth SJ, Tucci M, Leteurtre S, for the PlasmaTV investigators. Performance of the PEdiatric Logistic Organ Dysfunction-2 score in critically ill children requiring plasma transfusions. Annals Of Intensive Care 2016, 6: 98. PMID: 27714707, PMCID: PMC5053948, DOI: 10.1186/s13613-016-0197-6.Peer-Reviewed Original ResearchPELOD-2 scorePlasma transfusionIll childrenDay 1General pediatric intensive care unit populationPediatric Logistic Organ Dysfunction-2 scorePediatric intensive care unit populationIntensive care unit populationSpecific subpopulationsOrgan dysfunction scoreProspective observational studyHosmer-Lemeshow testObserved mortality ratePELOD-2Dysfunction scoreClinical outcomesOrgan failureResultsFour hundredClinical trialsScore scoresSerial evaluationAncillary studiesObservational studyTransfusionUnit population