2021
Epidemiology of Bleeding in Critically Ill Children
Sequeira J, Nellis ME, Karam O. Epidemiology of Bleeding in Critically Ill Children. Frontiers In Pediatrics 2021, 9: 699991. PMID: 34422724, PMCID: PMC8371326, DOI: 10.3389/fped.2021.699991.Peer-Reviewed Original ResearchPediatric critical care unitRisk of mortalityCritical care unitsIll childrenCare unitClinical outcomesProspective observational cohort studyEpidemiology of BleedingPICU-free daysPercent of patientsVentilator-free daysDuration of surgeryObservational cohort studyCritically Ill ChildrenWorse clinical outcomesType of surgeryFurther multicenter studiesHigher severityCohort studyCritical illnessPediatric IndexSevere complicationsConsecutive patientsIll patientsMedian age
2019
Quantifiable Bleeding in Children Supported by Extracorporeal Membrane Oxygenation and Outcome.
Nellis ME, Dalton H, Karam O. Quantifiable Bleeding in Children Supported by Extracorporeal Membrane Oxygenation and Outcome. Critical Care Medicine 2019, 47: e886-e892. PMID: 31449061, PMCID: PMC8608374, DOI: 10.1097/ccm.0000000000003968.Peer-Reviewed Original ResearchConceptsChest tube bleedingExtracorporeal membrane oxygenationCollaborative Pediatric Critical Care Research NetworkMembrane oxygenationChest tubeClinical outcomesPlatelet countML/Large observational cohort studyEunice Kennedy Shriver National InstituteCritical Care Research NetworkPICU-free daysPercent of patientsObservational cohort studyWorse clinical outcomesHuman Development Collaborative Pediatric Critical Care Research NetworkMembrane oxygenation specialistsHospital mortalityTransfusion volumeCohort studyHeparin doseConsecutive patientsThrombotic eventsPediatric institutionHemostatic tests
2017
Hypoglycemic relapse in term infants treated with glucose infusion
Sternberg J, Pfister R, Karam O. Hypoglycemic relapse in term infants treated with glucose infusion. Journal Of Clinical Neonatology 2017, 6: 163-167. DOI: 10.4103/jcn.jcn_10_17.Peer-Reviewed Original ResearchLow birth weightGlucose infusionBirth weightSingle-center retrospective studyProportion of infantsMain risk factorsTerm infantsConsecutive patientsNeonatal hypoglycemiaTerm newbornsGestational ageRetrospective studyRisk infantsRisk factorsMild severityRelapseInfusionProgressive weaningInfantsHypoglycemiaNewbornsSmall proportionLittle evidenceLevel 3Patients
2010
Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study
Karam O, Tucci M, Bateman ST, Ducruet T, Spinella PC, Randolph AG, Lacroix J. Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. Critical Care 2010, 14: r57. PMID: 20377853, PMCID: PMC2887178, DOI: 10.1186/cc8953.Peer-Reviewed Original ResearchConceptsPediatric intensive care unitMultiple organ dysfunction syndromeRed blood cell unitsOrgan dysfunction syndromeDysfunction syndromeIll childrenPICU lengthClinical outcomesOdds ratioObservational studyMultiple logistic regression modelProspective observational studyWorse clinical outcomesPrimary outcome measureIntensive care unitNorth American centersCell unitsLogistic regression modelsSecondary outcomesConsecutive patientsOrgan dysfunctionCare unitMedian lengthProspective studyClinical impact
2009
Blunt Abdominal Trauma in Children: A Score to Predict the Absence of Organ Injury
Karam O, Sanchez O, Chardot C, La Scala G. Blunt Abdominal Trauma in Children: A Score to Predict the Absence of Organ Injury. The Journal Of Pediatrics 2009, 154: 912-917. PMID: 19230903, DOI: 10.1016/j.jpeds.2009.01.001.Peer-Reviewed Original ResearchConceptsBlunt abdominal traumaIU/LNegative predictive valueAbdominal Doppler ultrasoundAbdominal traumaOrgan injuryDoppler ultrasoundIntra-abdominal organ injuryWhite blood cell countGood negative predictive valueIntra-abdominal injuriesTertiary care hospitalIntra-abdominal lesionsBlood cell countSystematic CT scanAbdominal painPeritoneal irritationHemodynamic instabilityInitial workupCare hospitalConsecutive patientsHospital admissionStable patientsAlanine aminotransferaseCT scan