2024
Child routines moderate a brief behavioral intervention to enhance sleep in school-aged children
Gebre A, Hawley N, Carskadon M, Raynor H, Jelalian E, Owens J, Wing R, Hart C. Child routines moderate a brief behavioral intervention to enhance sleep in school-aged children. Journal Of Pediatric Psychology 2024, 49: 365-371. PMID: 38553029, PMCID: PMC11098045, DOI: 10.1093/jpepsy/jsae015.Peer-Reviewed Original ResearchConceptsMonths post-randomizationSchool-aged childrenBehavioral sleep interventionsPost-randomizationBehavioral interventionsSleep interventionsChild routinesChild Routines InventoryEnhance sleepIntervention groupRoutine behaviorSecondary analysisSleep periodIntervention responseInterventionShort sleepWrist actigraphyModeration analysisRoutines InventoryPROCESS macroBehavior modificationChildrenBaselineTreatment conditionsSleep
2023
Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma
Recto K, Kachroo P, Huan T, Van Den Berg D, Lee G, Bui H, Lee D, Gereige J, Yao C, Hwang S, Joehanes R, Weiss S, Consortium N, Abe N, Abecasis G, Aguet F, Albert C, Almasy L, Alonso A, Ament S, Anderson P, Anugu P, Applebaum-Bowden D, Ardlie K, Arking D, Arnett D, Ashley-Koch A, Aslibekyan S, Assimes T, Auer P, Avramopoulos D, Ayas N, Balasubramanian A, Barnard J, Barnes K, Barr R, Barron-Casella E, Barwick L, Beaty T, Beck G, Becker D, Becker L, Beer R, Beitelshees A, Benjamin E, Benos T, Bezerra M, Bielak L, Bis J, Blackwell T, Blangero J, Blue N, Boerwinkle E, Bowden D, Bowler R, Brody J, Broeckel U, Broome J, Brown D, Bunting K, Burchard E, Bustamante C, Buth E, Cade B, Cardwell J, Carey V, Carrier J, Carson A, Carty C, Casaburi R, Romero J, Casella J, Castaldi P, Chaffin M, Chang C, Chang Y, Chasman D, Chavan S, Chen B, Chen W, Chen Y, Cho M, Choi S, Chuang L, Chung M, Chung R, Clish C, Comhair S, Conomos M, Cornell E, Correa A, Crandall C, Crapo J, Cupples L, Curran J, Curtis J, Custer B, Damcott C, Darbar D, David S, Davis C, Daya M, de Andrade M, de las Fuentes L, de Vries P, DeBaun M, Deka R, DeMeo D, Devine S, Dinh H, Doddapaneni H, Duan Q, Dugan-Perez S, Duggirala R, Durda J, Dutcher S, Eaton C, Ekunwe L, Boueiz A, Ellinor P, Emery L, Erzurum S, Farber C, Farek J, Fingerlin T, Flickinger M, Fornage M, Franceschini N, Frazar C, Fu M, Fullerton S, Fulton L, Gabriel S, Gan W, Gao S, Gao Y, Gass M, Geiger H, Gelb B, Geraci M, Germer S, Gerszten R, Ghosh A, Gibbs R, Gignoux C, Gladwin M, Glahn D, Gogarten S, Gong D, Goring H, Graw S, Gray K, Grine D, Gross C, Gu C, Guan Y, Guo X, Gupta N, Haessler J, Hall M, Han Y, Hanly P, Harris D, Hawley N, He J, Heavner B, Heckbert S, Hernandez R, Herrington D, Hersh C, Hidalgo B, Hixson J, Hobbs B, Hokanson J, Hong E, Hoth K, Hsiung C, Hu J, Hung Y, Huston H, Hwu C, Irvin M, Jackson R, Jain D, Jaquish C, Johnsen J, Johnson A, Johnson C, Johnston R, Jones K, Kang H, Kaplan R, Kardia S, Kelly S, Kenny E, Kessler M, Khan A, Khan Z, Kim W, Kimoff J, Kinney G, Konkle B, Kooperberg C, Kramer H, Lange C, Lange E, Lange L, Laurie C, Laurie C, LeBoff M, Lee J, Lee S, Lee W, LeFaive J, Levine D, Levy D, Lewis J, Li X, Li Y, Lin H, Lin H, Lin X, Liu S, Liu Y, Liu Y, Loos R, Lubitz S, Lunetta K, Luo J, Magalang U, Mahaney M, Make B, Manichaikul A, Manning A, Manson J, Martin L, Marton M, Mathai S, Mathias R, May S, McArdle P, McDonald M, McFarland S, McGarvey S, McGoldrick D, McHugh C, McNeil B, Mei H, Meigs J, Menon V, Mestroni L, Metcalf G, Meyers D, Mignot E, Mikulla J, Min N, Minear M, Minster R, Mitchell B, Moll M, Momin Z, Montasser M, Montgomery C, Muzny D, Mychaleckyj J, Nadkarni G, Naik R, Naseri T, Natarajan P, Nekhai S, Nelson S, Neltner B, Nessner C, Nickerson D, Nkechinyere O, North K, O'Connell J, O'Connor T, Ochs-Balcom H, Okwuonu G, Pack A, Paik D, Palmer N, Pankow J, Papanicolaou G, Parker C, Peloso G, Peralta J, Perez M, Perry J, Peters U, Peyser P, Phillips L, Pleiness J, Pollin T, Post W, Becker J, Boorgula M, Preuss M, Psaty B, Qasba P, Qiao D, Qin Z, Rafaels N, Raffield L, Rajendran M, Ramachandran V, Rao D, Rasmussen-Torvik L, Ratan A, Redline S, Reed R, Reeves C, Regan E, Reiner A, Reupena M, Rice K, Rich S, Robillard R, Robine N, Roden D, Roselli C, Rotter J, Ruczinski I, Runnels A, Russell P, Ruuska S, Ryan K, Sabino E, Saleheen D, Salimi S, Salvi S, Salzberg S, Sandow K, Sankaran V, Santibanez J, Schwander K, Schwartz D, Sciurba F, Seidman C, Seidman J, Sériès F, Sheehan V, Sherman S, Shetty A, Shetty A, Sheu W, Shoemaker M, Silver B, Silverman E, Skomro R, Smith A, Smith J, Smith J, Smith N, Smith T, Smoller S, Snively B, Snyder M, Sofer T, Sotoodehnia N, Stilp A, Storm G, Streeten E, Su J, Sung Y, Sylvia J, Szpiro A, Taliun D, Tang H, Taub M, Taylor K, Taylor M, Taylor S, Telen M, Thornton T, Threlkeld M, Tinker L, Tirschwell D, Tishkoff S, Tiwari H, Tong C, Tracy R, Tsai M, Vaidya D, Van Den Berg D, VandeHaar P, Vrieze S, Walker T, Wallace R, Walts A, Wang F, Wang H, Wang J, Watson K, Watt J, Weeks D, Weinstock J, Weir B, Weiss S, Weng L, Wessel J, Willer C, Williams K, Williams L, Williams S, Wilson C, Wilson J, Winterkorn L, Wong Q, Wu B, Wu J, Xu H, Yanek L, Yang I, Yu K, Zekavat S, Zhang Y, Zhao S, Zhao W, Zhu X, Ziv E, Zody M, Zoellner S, O’Connor G, Levy D, DeMeo D. Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma. EBioMedicine 2023, 95: 104758. PMID: 37598461, PMCID: PMC10462855, DOI: 10.1016/j.ebiom.2023.104758.Peer-Reviewed Original ResearchConceptsMethylation quantitative trait lociAssociation studiesNovel epigenetic signatureIdentifies novel targetsQuantitative trait lociTranscription factor bindingEpigenome-wide association studiesGene ontology analysisWide association studyClosest genesTrait lociCausal regulatorsDrug target analysisTranscription patternsOntology analysisDNA methylationEpigenetic signaturesFactor bindingGene expressionMolecular mechanismsMendelian randomizationCosta Rica StudyPotential therapeutic targetNovel targetGenetic epidemiologyCross-sectional and prospective associations between household socioeconomic resources, appetite traits, and body size among Samoan infants
Oyama S, Arslanian K, Fidow U, Naseri T, Soti-Ulberg C, Hawley N. Cross-sectional and prospective associations between household socioeconomic resources, appetite traits, and body size among Samoan infants. Appetite 2023, 185: 106519. PMID: 36870391, DOI: 10.1016/j.appet.2023.106519.Peer-Reviewed Original ResearchScoping review protocol of multicomponent interventions to address cardiometabolic disease risk among Pacific Islander children
Choy C, Nyhan K, Savusa K, Soti-Ulberg C, Rosen R, Naseri T, Hawley N, Sharifi M. Scoping review protocol of multicomponent interventions to address cardiometabolic disease risk among Pacific Islander children. PLOS ONE 2023, 18: e0280888. PMID: 36689458, PMCID: PMC9870166, DOI: 10.1371/journal.pone.0280888.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPacific Islander childrenCMD risk factorsMulticomponent interventionRisk factorsCardiometabolic disease risk factorsDisease risk factorsCardiometabolic disease riskClinical trial registrationPreferred Reporting ItemsJoanna Briggs Institute ManualFormal ethical approvalTRIAL REGISTRATIONCochrane LibraryHigh prevalenceEligible interventionsStudy populationEthical approvalReporting ItemsCMD riskDisease riskIntervention componentsProQuest DissertationsReview protocolEvidence mappingEvidence synthesisPrediction of fat mass from anthropometry at ages 7 to 9 years in Samoans: a cross-sectional study in the Ola Tuputupua’e cohort
Choy C, Johnson W, Duckham R, Naseri T, Soti-Ulberg C, Reupena M, Braun J, McGarvey S, Hawley N. Prediction of fat mass from anthropometry at ages 7 to 9 years in Samoans: a cross-sectional study in the Ola Tuputupua’e cohort. European Journal Of Clinical Nutrition 2023, 77: 495-502. PMID: 36624192, PMCID: PMC7614464, DOI: 10.1038/s41430-022-01256-6.Peer-Reviewed Original ResearchConceptsFat massSex-specific prediction modelsCross-sectional studyAge 7 yearsHigh-risk settingsFuture obesity preventionModel development sampleSamoan childrenObesity prevalenceObesity preventionBody fatHigh riskSex-specific modelsBland-Altman limitsSubscapularSubstantial concordanceAge 7Pacific IslandersChildrenDXADevelopment samplePreventionConcordanceYearsValidation samplePrevalence of malnutrition among Samoan children aged 5 to 11 years in 2019–2020
Choy C, Lupematasila V, Arorae M, Tafunaina F, Unasa F, Soti-Ulberg C, Reupena M, Duckham R, Faasalele-Savusa K, Naseri T, Hawley N. Prevalence of malnutrition among Samoan children aged 5 to 11 years in 2019–2020. Annals Of Human Biology 2023, 50: 200-205. PMID: 37166449, PMCID: PMC10214481, DOI: 10.1080/03014460.2023.2197298.Peer-Reviewed Original ResearchConceptsOverweight/obesityExact testWorld Health Organization z scoreNutrition transitionPrevalence of malnutritionBody mass indexFisher's exact testComplete physical assessmentLevel of malnutritionComprehensive intervention strategiesAnemia prevalenceMass indexSamoan childrenHigh prevalenceObesityHemoglobin concentrationAnemiaZ-scorePhysical assessmentPrevalenceModerate stuntingUnderweightChi-squareMalnutritionChild's age
2022
Psychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis
Mew E, Nyhan K, Bonumwezi J, Blas V, Gorman H, Hennein R, Quach K, Shabanova V, Hawley N, Lowe S. Psychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis. PLOS ONE 2022, 17: e0276753. PMID: 36378630, PMCID: PMC9665367, DOI: 10.1371/journal.pone.0276753.Peer-Reviewed Original ResearchConceptsChild mental health outcomesSystematic review registrationRelevant study characteristicsMental health outcomesParental trauma exposureReview registrationBias assessmentRegistration IDConference abstractsPeer-reviewed publicationsPsychosocial factorsFamily-level factorsHealth outcomesSystematic reviewNarrative synthesisPsychosocial mediatorsPublication biasTrauma exposureStudy characteristicsEpidemiological researchProQuest DissertationsTraumaTrauma typesPsychological impactMediatorsA loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes
Bastard P, Hsiao KC, Zhang Q, Choin J, Best E, Chen J, Gervais A, Bizien L, Materna M, Harmant C, Roux M, Hawley NL, Weeks DE, McGarvey ST, Sandoval K, Barberena-Jonas C, Quinto-Cortés CD, Hagelberg E, Mentzer AJ, Robson K, Coulibaly B, Seeleuthner Y, Bigio B, Li Z, Uzé G, Pellegrini S, Lorenzo L, Sbihi Z, Latour S, Besnard M, de Beaumais T, Aigrain E, Béziat V, Deka R, Tulifau L, Viali S, Reupena M, Naseri T, McNaughton P, Sarkozy V, Peake J, Blincoe A, Primhak S, Stables S, Gibson K, Woon ST, Drake KM, Hill AVS, Chan CY, King R, Ameratunga R, Teiti I, Aubry M, Cao-Lormeau VM, Tangye SG, Zhang SY, Jouanguy E, Gray P, Abel L, Moreno-Estrada A, Minster RL, Quintana-Murci L, Wood AC, Casanova JL. A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes. Journal Of Experimental Medicine 2022, 219: e20220028. PMID: 35442418, PMCID: PMC9026234, DOI: 10.1084/jem.20220028.Peer-Reviewed Original ResearchIs overweight or obesity associated with anemia in children? Follow-up of Samoans in the Ola Tuputupua’e “Growing Up” study
Choy CC, Howe CJ, Soti-Ulberg C, Naseri T, Reupena MS, Duckham RL, Hawley NL. Is overweight or obesity associated with anemia in children? Follow-up of Samoans in the Ola Tuputupua’e “Growing Up” study. Obesity Research & Clinical Practice 2022, 16: 144-150. PMID: 35256305, PMCID: PMC9636893, DOI: 10.1016/j.orcp.2022.02.008.Peer-Reviewed Original ResearchConceptsOverweight/obesityObesity-related inflammationPrevalence ratiosIron deficiencyDouble burdenPrevalence of anemiaBody mass indexAge z-scorePoisson regression modelsCohort studyMass indexSamoan childrenHigh prevalenceObesityAnemiaZ-scoreCovariate adjustmentConfidence intervalsMicronutrient deficienciesInflammationChildrenPrevalenceFurther investigationRegression modelsDeficiency
2021
Randomized controlled trial to enhance children’s sleep, eating, and weight
Hart CN, Hawley NL, Coffman DL, Raynor HA, Carskadon MA, Jelalian E, Owens JA, Spaeth A, Wing RR. Randomized controlled trial to enhance children’s sleep, eating, and weight. Pediatric Research 2021, 92: 1075-1081. PMID: 34930967, PMCID: PMC9413537, DOI: 10.1038/s41390-021-01870-3.Peer-Reviewed Original ResearchConceptsBrief behavioral interventionChildren's sleepBehavioral interventionsBMI/BMI z-scoreSleep periodDomains of functioningNocturnal sleepMin/nightTreatment controlGood night's sleepSleep interventionsBrief interventionCaloric intakeLower BMIPercent caloriesNight sleepWeight regulationChildren 8Body mass index (BMI) changeSleepBMI z-scoreBackgroundThe present studyInterventionWeight statusPrimary outcomeSocial Support for Self-Care: Patient Strategies for Managing Diabetes and Hypertension in Rural Uganda
Tusubira AK, Nalwadda CK, Akiteng AR, Hsieh E, Ngaruiya C, Rabin TL, Katahoire A, Hawley NL, Kalyesubula R, Ssinabulya I, Schwartz JI, Armstrong-Hough M. Social Support for Self-Care: Patient Strategies for Managing Diabetes and Hypertension in Rural Uganda. Annals Of Global Health 2021, 87: 86. PMID: 34458110, PMCID: PMC8378074, DOI: 10.5334/aogh.3308.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesSelf-care practicesPrescribed medicinesConventional medicinePatient's social support networkRural UgandaSelf-care activitiesBlood sugar levelsCross-sectional qualitative studyResource-limited settingsSelf-care effortsSocial support networksSocial supportNCD clinicsNineteen patientsAdult patientsHealth facilitiesPatientsPatient strategiesManaging diabetesHypertensionSelf-CareDiabetesDiagnostic testsLow-income countriesComparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of Ola Tuputupua’e Data
Warmath CR, Choy CC, Frame EA, Sherar LB, Duckham RL, Soti-Ulberg C, Naseri T, Reupena MS, Hawley NL. Comparability of The Netherlands Physical Activity Questionnaire with Accelerometer-Measured Physical Activity in Samoan Children: A Retrospective Analysis of Ola Tuputupua’e Data. International Journal Of Environmental Research And Public Health 2021, 18: 8438. PMID: 34444185, PMCID: PMC8391931, DOI: 10.3390/ijerph18168438.Peer-Reviewed Original ResearchConceptsPhysical Activity QuestionnaireActivity QuestionnairePhysical activityHigh-intensity physical activityMonitor wear timePhysical activity levelsPhysical activity measurementPhysical activity dataAccelerometer outcomesCardiometabolic healthMixed longitudinal studyObesity developmentRetrospective analysisCombination of questionsChild growthWear timeActivity levelsMarginal meansAged childrenTertileScoresChildrenIndividual questionsQuestionnaireSamoan childrenFactorial validation analysis of the Baby and Children's Eating Behavior Questionnaires in Samoa
Oyama S, Arslanian KJ, Fidow UT, Naseri T, Soti-Ulberg C, Hawley NL. Factorial validation analysis of the Baby and Children's Eating Behavior Questionnaires in Samoa. Eating Behaviors 2021, 42: 101530. PMID: 34051664, PMCID: PMC8380697, DOI: 10.1016/j.eatbeh.2021.101530.Peer-Reviewed Original ResearchConceptsBaby Eating Behaviour QuestionnaireEating Behavior QuestionnaireMonths postpartumChildren's Eating Behaviour QuestionnaireInfant feeding behaviorsMother-infant dyadsBehavior QuestionnaireCEBQ scoresPediatric obesityElimination of factorsPostpartumTime pointsFurther qualitative researchCEBQEarly childhoodPacific IslandersLongitudinal analysisNine-itemMonthsFactor structureLow internal reliabilityInternal reliabilityThree-factor structureExploratory factor analysisQuestionnaire's factor structure
2020
Longitudinal Assessment of Childhood Dietary Patterns: Associations with Body Mass Index z-Score among Children in the Samoan Ola Tuputupua'e (Growing Up) Cohort
Choy CC, Wang D, Naseri T, Soti-Ulberg C, Reupena MS, Duckham RL, Baylin A, Hawley NL. Longitudinal Assessment of Childhood Dietary Patterns: Associations with Body Mass Index z-Score among Children in the Samoan Ola Tuputupua'e (Growing Up) Cohort. Childhood Obesity 2020, 16: 534-543. PMID: 32907355, PMCID: PMC7575349, DOI: 10.1089/chi.2020.0058.Peer-Reviewed Original ResearchConceptsDietary patternsHigh adherenceBody mass index zChildhood obesity prevention strategiesObesity prevention strategiesBody mass indexFood frequency dataChildhood dietary patternsBiological mother-child dyadsCohort studyMass indexPattern adherencePotential confoundersChildhood obesityPrevention strategiesMother-child dyadsLongitudinal assessmentTime pointsConvenience sampleAdherenceBMIzIntervention strategiesChildrenScoresAssociationPiloting a food photo sorting activity in Samoa to assess maternal beliefs and their role in child diet
Tanawattanacharoen VK, Choy CC, Anesi TJ, Naseri T, Soti‐Ulberg C, Reupena MS, Hawley NL. Piloting a food photo sorting activity in Samoa to assess maternal beliefs and their role in child diet. Maternal And Child Nutrition 2020, 16: e12974. PMID: 32056393, PMCID: PMC7296816, DOI: 10.1111/mcn.12974.Peer-Reviewed Original ResearchConceptsChildren's dietary intakeDietary intakeChildhood obesityChildren's dietsHealthier child dietMaternal beliefsAlarming burdenSamoan mothersKnowledge/beliefsNutritional knowledgeEating habitsNutritional expertsIntakeHealthy foodsMothersObesityCountry settingsCost of foodStatusDietPearson correlationFood costsAdditional supportParental beliefsFood