Loss of Peristaltic Reserve, Determined by Multiple Rapid Swallows, Is the Most Frequent Esophageal Motility Abnormality in Patients With Systemic Sclerosis
Carlson DA, Crowell MD, Kimmel JN, Patel A, Gyawali CP, Hinchcliff M, Griffing WL, Pandolfino JE, Vela MF. Loss of Peristaltic Reserve, Determined by Multiple Rapid Swallows, Is the Most Frequent Esophageal Motility Abnormality in Patients With Systemic Sclerosis. Clinical Gastroenterology And Hepatology 2016, 14: 1502-1506. PMID: 27062902, PMCID: PMC5028229, DOI: 10.1016/j.cgh.2016.03.039.Peer-Reviewed Original ResearchConceptsMultiple rapid swallowsHigh-resolution manometrySystemic sclerosisDistal contractile integralPeristaltic reserveEsophageal motility diagnosisRapid swallowsMotility diagnosisContractile integralEsophageal motility findingsEsophageal high-resolution manometryTertiary referral centerIneffective esophageal motilityMedian distal contractile integralEsophageal motility abnormalitiesEsophageal motility disordersAbsent contractilityHRM findingsMotility findingsReferral centerEsophageal motilityMotility abnormalitiesMotility disordersRetrospective analysisSupine swallowsThe association between systemic sclerosis disease manifestations and esophageal high‐resolution manometry parameters
Kimmel JN, Carlson DA, Hinchcliff M, Carns MA, Aren KA, Lee J, Pandolfino JE. The association between systemic sclerosis disease manifestations and esophageal high‐resolution manometry parameters. Neurogastroenterology & Motility 2016, 28: 1157-1165. PMID: 26921101, PMCID: PMC4956560, DOI: 10.1111/nmo.12813.Peer-Reviewed Original ResearchConceptsHigh-resolution manometrySSc disease durationClinical characteristicsMotility diagnosisNormal motilityHigh-resolution manometry parametersSevere esophageal dysfunctionWorse lung functionIneffective esophageal motilityPulmonary function testsRetrospective chart reviewRodnan skin scoreSkin disease severitySymptoms of dysphagiaAbsent contractilityEsophageal dysfunctionChart reviewSkin involvementSSc patientsLung functionSkin scoreSystemic manifestationsSystemic sclerosisEsophageal contractilityEsophageal motility