2017
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016
Collaborators G, Wang H, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abera S, Abraha H, Abu-Raddad L, Abu-Rmeileh N, Adedeji I, Adedoyin R, Adetifa I, Adetokunboh O, Afshin A, Aggarwal R, Agrawal A, Agrawal S, Kiadaliri A, Ahmed M, Aichour M, Aichour A, Aichour I, Aiyar S, Akanda A, Akinyemiju T, Akseer N, Al Lami F, Alabed S, Alahdab F, Al-Aly Z, Alam K, Alam N, Alasfoor D, Aldridge R, Alene K, Al-Eyadhy A, Alhabib S, Ali R, Alizadeh-Navaei R, Aljunid S, Alkaabi J, Alkerwi A, Alla F, Allam S, Allebeck P, Al-Raddadi R, Alsharif U, Altirkawi K, Alvis-Guzman N, Amare A, Ameh E, Amini E, Ammar W, Amoako Y, Anber N, Andrei C, Androudi S, Ansari H, Ansha M, Antonio C, Anwari P, Ärnlöv J, Arora M, Artaman A, Aryal K, Asayesh H, Asgedom S, Asghar R, Assadi R, Assaye A, Atey T, Atre S, Avila-Burgos L, Avokpaho E, Awasthi A, Babalola T, Bacha U, Badawi A, Balakrishnan K, Balalla S, Barac A, Barber R, Barboza M, Barker-Collo S, Bärnighausen T, Barquera S, Barregard L, Barrero L, Baune B, Bazargan-Hejazi S, Bedi N, Beghi E, Béjot Y, Bekele B, Bell M, Bello A, Bennett D, Bennett J, Bensenor I, Benson J, Berhane A, Berhe D, Bernabé E, Beuran M, Beyene A, Bhala N, Bhansali A, Bhaumik S, Bhutta Z, Bicer B, Bidgoli H, Bikbov B, Birungi C, Biryukov S, Bisanzio D, Bizuayehu H, Bjerregaard P, Blosser C, Boneya D, Boufous S, Bourne R, Brazinova A, Breitborde N, Brenner H, Brugha T, Bukhman G, Bulto L, Bumgarner B, Burch M, Butt Z, Cahill L, Cahuana-Hurtado L, Campos-Nonato I, Car J, Car M, Cárdenas R, Carpenter D, Carrero J, Carter A, Castañeda-Orjuela C, Castro F, Castro R, Catalá-López F, Chen H, Chiang P, Chibalabala M, Chisumpa V, Chitheer A, Choi J, Christensen H, Christopher D, Ciobanu L, Cirillo M, Cohen A, Colquhoun S, Coresh J, Criqui M, Cromwell E, Crump J, Dandona L, Dandona R, Dargan P, Neves J, Davey G, Davitoiu D, Davletov K, de Courten B, De Leo D, Degenhardt L, Deiparine S, Dellavalle R, Deribe K, Deribew A, Jarlais D, Dey S, Dharmaratne S, Dherani M, Diaz-Torné C, Ding E, Dixit P, Djalalinia S, Phuc H, Doku D, Donnelly C, dos Santos K, Douwes-Schultz D, Driscoll T, Duan L, Dubey M, Duncan B, Dwivedi L, Ebrahimi H, Bcheraoui C, Ellingsen C, Enayati A, Endries A, Ermakov S, Eshetie S, Eshrati B, Eskandarieh S, Esteghamati A, Estep K, Fanuel F, Faro A, Farvid M, Farzadfar F, Feigin V, Fereshtehnejad S, Fernandes J, Fernandes J, Feyissa T, Filip I, Fischer F, Foigt N, Foreman K, Frank T, Franklin R, Fraser M, Friedman J, Frostad J, Fullman N, Fürst T, Furtado J, Futran N, Gakidou E, Gambashidze K, Gamkrelidze A, Gankpé F, Garcia-Basteiro A, Gebregergs G, Gebrehiwot T, Gebrekidan K, Gebremichael M, Gelaye A, Geleijnse J, Gemechu B, Gemechu K, Genova-Maleras R, Gesesew H, Gething P, Gibney K, Gill P, Gillum R, Giref A, Girma B, Giussani G, Goenka S, Gomez B, Gona P, Gopalani S, Goulart A, Graetz N, Gugnani H, Gupta P, Gupta R, Gupta R, Gupta T, Gupta V, Haagsma J, Hafezi-Nejad N, Hakuzimana A, Halasa Y, Hamadeh R, Hambisa M, Hamidi S, Hammami M, Hancock J, Handal A, Hankey G, Hao Y, Harb H, Hareri H, Harikrishnan S, Haro J, Hassanvand M, Havmoeller R, Hay R, Hay S, He F, Heredia-Pi I, Herteliu C, Hilawe E, Hoek H, Horita N, Hosgood H, Hostiuc S, Hotez P, Hoy D, Hsairi M, Htet A, Hu G, Huang J, Huang H, Iburg K, Igumbor E, Ileanu B, Inoue M, Irenso A, Irvine C, Islam M, Islam N, Jacobsen K, Jaenisch T, Jahanmehr N, Jakovljevic M, Javanbakht M, Jayatilleke A, Jeemon P, Jensen P, Jha V, Jin Y, John D, John O, Johnson S, Jonas J, Jürisson M, Kabir Z, Kadel R, Kahsay A, Kalkonde Y, Kamal R, Kan H, Karch A, Karema C, Karimi S, Karthikeyan G, Kasaeian A, Kassaw N, Kassebaum N, Kastor A, Katikireddi S, Kaul A, Kawakami N, Kazanjan K, Keiyoro P, Kelbore S, Kemp A, Kengne A, Keren A, Kereselidze M, Kesavachandran C, Ketema E, Khader Y, Khalil I, Khan E, Khan G, Khang Y, Khera S, Khoja A, Khosravi M, Kibret G, Kieling C, Kim Y, Kim C, Kim D, Kim P, Kim S, Kimokoti R, Kinfu Y, Kishawi S, Kissoon N, Kivimaki M, Knudsen A, Kokubo Y, Kopec J, Kosen S, Koul P, Koyanagi A, Kravchenko M, Krohn K, Defo B, Kuipers E, Kulikoff X, Kulkarni V, Kumar G, Kumar P, Kumsa F, Kutz M, Lachat C, Lagat A, Lager A, Lal D, Lalloo R, Lambert N, Lan Q, Lansingh V, Larson H, Larsson A, Laryea D, Lavados P, Laxmaiah A, Lee P, Leigh J, Leung J, Leung R, Levi M, Li Y, Liao Y, Liben M, Lim S, Linn S, Lipshultz S, Liu S, Lodha R, Logroscino G, Lorch S, Lorkowski S, Lotufo P, Lozano R, Lunevicius R, Lyons R, Ma S, Macarayan E, Machado I, Mackay M, Razek M, Magis-Rodriguez C, Mahdavi, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malhotra R, Malta D, Mantovani L, Manyazewal T, Mapoma C, Marczak L, Marks G, Martin E, Martinez-Raga J, Martins-Melo F, Massano J, Maulik P, Mayosi B, Mazidi M, McAlinden C, McGarvey S, McGrath J, McKee M, Mehata S, Mehndiratta M, Mehta K, Meier T, Mekonnen T, Meles K, Memiah P, Memish Z, Mendoza W, Mengesha M, Mengistie M, Mengistu D, Menon G, Menota B, Mensah G, Meretoja T, Meretoja A, Mezgebe H, Micha R, Mikesell J, Miller T, Mills E, Minnig S, Mirarefin M, Mirrakhimov E, Misganaw A, Mishra S, Mohammad K, Mohammadi A, Mohammed K, Mohammed S, Mohan M, Mohanty S, Mokdad A, Mollenkopf S, Molokhia M, Monasta L, Hernandez J, Montico M, Mooney M, Moore A, Moradi-Lakeh M, Moraga P, Morawska L, Mori R, Morrison S, Mruts K, Mueller U, Mullany E, Muller K, Murthy G, Murthy S, Musa K, Nachega J, Nagata C, Nagel G, Naghavi M, Naidoo K, Nanda L, Nangia V, Nascimento B, Natarajan G, Negoi I, Nguyen C, Le Nguyen Q, Nguyen T, Nguyen G, Ningrum D, Nisar M, Nomura M, Nong V, Norheim O, Norrving B, Noubiap J, Nyakarahuka L, O'Donnell M, Obermeyer C, Ogbo F, Oh I, Okoro A, Oladimeji O, Olagunju A, Olusanya B, Olusanya J, Oren E, Ortiz A, Osgood-Zimmerman A, Ota E, Owolabi M, Oyekale A, Mahesh P, Pacella R, Pakhale S, Pana A, Panda B, Panda-Jonas S, Park E, Parsaeian M, Patel T, Patten S, Patton G, Paudel D, Pereira D, Perez-Padilla R, Perez-Ruiz F, Perico N, Pervaiz A, Pesudovs K, Peterson C, Petri W, Petzold M, Phillips M, Piel F, Pigott D, Pishgar F, Plass D, Polinder S, Popova S, Postma M, Poulton R, Pourmalek F, Prasad N, Purwar M, Qorbani M, Quintanilla B, Rabiee R, Radfar A, Rafay A, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman M, Rahman S, Rahman M, Kumar R, Rajsic S, Ram U, Rana S, Ranabhat C, Rao P, Rawaf S, Ray S, Rego M, Rehm J, Reiner R, Remuzzi G, Renzaho A, Resnikoff S, Rezaei S, Rezai M, Ribeiro A, Rivas J, Rokni M, Ronfani L, Roshandel G, Roth G, Rothenbacher D, Roy A, Rubagotti E, Ruhago G, Saadat S, Sabde Y, Sachdev P, Sadat N, Safdarian, Safi S, Safiri S, Sagar R, Sahathevan R, Sahebkar A, Sahraian M, Salama J, Salamati P, Salomon J, Salvi S, Samy A, Sanabria J, Sanchez-Niño M, Santos I, Milicevic M, Sarmiento-Suarez R, Sartorius B, Satpathy M, Sawhney M, Saxena S, Saylan M, Schmidt M, Schneider I, Schulhofer-Wohl S, Schutte A, Schwebel D, Schwendicke F, Seedat S, Seid A, Sepanlou S, Servan-Mori E, Shackelford K, Shaheen A, Shahraz S, Shaikh M, Shamsipour M, Shamsizadeh M, Sharma J, Sharma R, She J, Shen J, Shetty B, Shi P, Shibuya K, Shifa G, Shigematsu M, Shiri R, Shiue I, Shrime M, Sigfusdottir I, Silberberg D, Silpakit N, Silva D, Silva J, Silveira D, Sindi S, Singh J, Singh P, Singh A, Singh V, Sinha D, Skarbek K, Skiadaresi E, Sligar A, Smith D, Sobaih B, Sobngwi E, Soneji S, Soriano J, Sreeramareddy C, Srinivasan V, Stathopoulou V, Steel N, Stein D, Steiner C, Stöckl H, Stokes M, Strong M, Sufiyan M, Suliankatchi R, Sunguya B, Sur P, Swaminathan S, Sykes B, Szoeke C, Tabarés-Seisdedos R, Tadakamadla S, Tadese F, Tandon N, Tanne D, Tarajia M, Tavakkoli M, Taveira N, Tehrani-Banihashemi A, Tekelab T, Tekle D, Temsah M, Terkawi A, Tesema C, Tesssema B, Theis A, Thomas N, Thompson A, Thomson A, Thrift A, Tiruye T, Tobe-Gai R, Tonelli M, Topor-Madry R, Topouzis F, Tortajada M, Tran B, Truelsen T, Trujillo U, Tsilimparis N, Tuem K, Tuzcu E, Tyrovolas S, Ukwaja K, Undurraga E, Uthman O, Uzochukwu B, van Boven J, Varakin Y, Varughese S, Vasankari T, Vasconcelos A, Velasquez I, Venketasubramanian N, Vidavalur R, Violante F, Vishnu A, Vladimirov S, Vlassov V, Vollset S, Vos T, Waid J, Wakayo T, Wang Y, Weichenthal S, Weiderpass E, Weintraub R, Werdecker A, Wesana J, Wijeratne T, Wilkinson J, Wiysonge C, Woldeyes B, Wolfe C, Workicho A, Workie S, Xavier D, Xu G, Yaghoubi M, Yakob B, Yalew A, Yan L, Yano Y, Yaseri M, Ye P, Yimam H, Yip P, Yirsaw B, Yonemoto N, Yoon S, Yotebieng M, Younis M, Zaidi Z, Zaki M, Zeeb H, Zenebe Z, Zerfu T, Zhang A, Zhang X, Zodpey S, Zuhlke L, Lopez A, Murray C. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet 2017, 390: 1084-1150. PMID: 28919115, PMCID: PMC5605514, DOI: 10.1016/s0140-6736(17)31833-0.Peer-Reviewed Original ResearchConceptsSocio-demographic IndexMortality rateDeath rateAge groupsAge-sex groupsAge-specific death ratesCause mortalityLife expectancyRegistration of deathsGlobal burdenBirth historyNational InstituteAge-specific mortalityAge-standardised death rateRisk Factors Study 2016Young adult age groupDisease Study 2016Rate of stillbirthSex-specific death ratesCivil Registration SystemAdult age groupsHigher life expectancyEpidemic infectious diseasesHIV/AIDSFemale life expectancy
2016
Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Collaborators G, Vos T, Allen C, Arora M, Barber R, Bhutta Z, Brown A, Carter A, Casey D, Charlson F, Chen A, Coggeshall M, Cornaby L, Dandona L, Dicker D, Dilegge T, Erskine H, Ferrari A, Fitzmaurice C, Fleming T, Forouzanfar M, Fullman N, Gething P, Goldberg E, Graetz N, Haagsma J, Hay S, Johnson C, Kassebaum N, Kawashima T, Kemmer L, Khalil I, Kinfu Y, Kyu H, Leung J, Liang X, Lim S, Lopez A, Lozano R, Marczak L, Mensah G, Mokdad A, Naghavi M, Nguyen G, Nsoesie E, Olsen H, Pigott D, Pinho C, Rankin Z, Reinig N, Salomon J, Sandar L, Smith A, Stanaway J, Steiner C, Teeple S, Thomas B, Troeger C, Wagner J, Wang H, Wanga V, Whiteford H, Zoeckler L, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abraham B, Abubakar I, Abu-Raddad L, Abu-Rmeileh N, Ackerman I, Adebiyi A, Ademi Z, Adou A, Afanvi K, Agardh E, Agarwal A, Kiadaliri A, Ahmadieh H, Ajala O, Akinyemi R, Akseer N, Al-Aly Z, Alam K, Alam N, Aldhahri S, Alegretti M, Alemu Z, Alexander L, Alhabib S, Ali R, Alkerwi A, Alla F, Allebeck P, Al-Raddadi R, Alsharif U, Altirkawi K, Alvis-Guzman N, Amare A, Amberbir A, Amini H, Ammar W, Amrock S, Andersen H, Anderson G, Anderson B, Antonio C, Aregay A, Ärnlöv J, Artaman A, Asayesh H, Assadi R, Atique S, Avokpaho E, Awasthi A, Quintanilla B, Azzopardi P, Bacha U, Badawi A, Balakrishnan K, Banerjee A, Barac A, Barker-Collo S, Bärnighausen T, Barregard L, Barrero L, Basu A, Bazargan-Hejazi S, Beghi E, Bell B, Bell M, Bennett D, Bensenor I, Benzian H, Berhane A, Bernabé E, Betsu B, Beyene A, Bhala N, Bhatt S, Biadgilign S, Bienhoff K, Bikbov B, Biryukov S, Bisanzio D, Bjertness E, Blore J, Borschmann R, Boufous S, Brainin M, Brazinova A, Breitborde N, Brown J, Buchbinder R, Buckle G, Butt Z, Calabria B, Campos-Nonato I, Campuzano J, Carabin H, Cárdenas R, Carpenter D, Carrero J, Castañeda-Orjuela C, Rivas J, Catalá-López F, Chang J, Chiang P, Chibueze C, Chisumpa V, Choi J, Chowdhury R, Christensen H, Christopher D, Ciobanu L, Cirillo M, Coates M, Colquhoun S, Cooper C, Cortinovis M, Crump J, Damtew S, Dandona R, Daoud F, Dargan P, Neves J, Davey G, Davis A, De Leo D, Degenhardt L, Del Gobbo L, Dellavalle R, Deribe K, Deribew A, Derrett S, Jarlais D, Dharmaratne S, Dhillon P, Diaz-Torné C, Ding E, Driscoll T, Duan L, Dubey M, Duncan B, Ebrahimi H, Ellenbogen R, Elyazar I, Endres M, Endries A, Ermakov S, Eshrati B, Estep K, Farid T, Farinha C, Faro A, Farvid M, Farzadfar F, Feigin V, Felson D, Fereshtehnejad S, Fernandes J, Fernandes J, Fischer F, Fitchett J, Foreman K, Fowkes F, Fox J, Franklin R, Friedman J, Frostad J, Fürst T, Futran N, Gabbe B, Ganguly P, Gankpé F, Gebre T, Gebrehiwot T, Gebremedhin A, Geleijnse J, Gessner B, Gibney K, Ginawi I, Giref A, Giroud M, Gishu M, Giussani G, Glaser E, Godwin W, Gomez-Dantes H, Gona P, Goodridge A, Gopalani S, Gotay C, Goto A, Gouda H, Grainger R, Greaves F, Guillemin F, Guo Y, Gupta R, Gupta R, Gupta V, Gutiérrez R, Haile D, Hailu A, Hailu G, Halasa Y, Hamadeh R, Hamidi S, Hammami M, Hancock J, Handal A, Hankey G, Hao Y, Harb H, Harikrishnan S, Haro J, Havmoeller R, Hay R, Heredia-Pi I, Heydarpour P, Hoek H, Horino M, Horita N, Hosgood H, Hoy D, Htet A, Huang H, Huang J, Huynh C, Iannarone M, Iburg K, Innos K, Inoue M, Iyer V, Jacobsen K, Jahanmehr N, Jakovljevic M, Javanbakht M, Jayaraman S, Jayatilleke A, Jee S, Jeemon P, Jensen P, Jiang Y, Jibat T, Jimenez-Corona A, Jin Y, Jonas J, Kabir Z, Kalkonde Y, Kamal R, Kan H, Karch A, Karema C, Karimkhani C, Kasaeian A, Kaul A, Kawakami N, Keiyoro P, Kemp A, Keren A, Kesavachandran C, Khader Y, Khan A, Khan E, Khang Y, Khera S, Khoja T, Khubchandani J, Kieling C, Kim P, Kim C, Kim D, Kim Y, Kissoon N, Knibbs L, Knudsen A, Kokubo Y, Kolte D, Kopec J, Kosen S, Kotsakis G, Koul P, Koyanagi A, Kravchenko M, Defo B, Bicer B, Kudom A, Kuipers E, Kumar G, Kutz M, Kwan G, Lal A, Lalloo R, Lallukka T, Lam H, Lam J, Langan S, Larsson A, Lavados P, Leasher J, Leigh J, Leung R, Levi M, Li Y, Li Y, Liang J, Liu S, Liu Y, Lloyd B, Lo W, Logroscino G, Looker K, Lotufo P, Lunevicius R, Lyons R, Mackay M, Magdy M, Razek A, Mahdavi, Majdan M, Majeed A, Malekzadeh R, Marcenes W, Margolis D, Martinez-Raga J, Masiye F, Massano J, McGarvey S, McGrath J, McKee M, McMahon B, Meaney P, Mehari A, Mejia-Rodriguez F, Mekonnen A, Melaku Y, Memiah P, Memish Z, Mendoza W, Meretoja A, Meretoja T, Mhimbira F, Millear A, Miller T, Mills E, Mirarefin M, Mitchell P, Mock C, Mohammadi A, Mohammed S, Monasta L, Hernandez J, Montico M, Mooney M, Moradi-Lakeh M, Morawska L, Mueller U, Mullany E, Mumford J, Murdoch M, Nachega J, Nagel G, Naheed A, Naldi L, Nangia V, Newton J, Ng M, Ngalesoni F, Le Nguyen Q, Nisar M, Pete P, Nolla J, Norheim O, Norman R, Norrving B, Nunes B, Ogbo F, Oh I, Ohkubo T, Olivares P, Olusanya B, Olusanya J, Ortiz A, Osman M, Ota E, Mahesh P, Park E, Parsaeian M, de Azeredo Passos V, Caicedo A, Patten S, Patton G, Pereira D, Perez-Padilla R, Perico N, Pesudovs K, Petzold M, Phillips M, Piel F, Pillay J, Pishgar F, Plass D, Platts-Mills J, Polinder S, Pond C, Popova S, Poulton R, Pourmalek F, Prabhakaran D, Prasad N, Qorbani M, Rabiee R, Radfar A, Rafay A, Rahimi K, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman S, Kumar R, Rajsic S, Ram U, Rao P, Refaat A, Reitsma M, Remuzzi G, Resnikoff S, Reynolds A, Ribeiro A, Blancas M, Roba H, Rojas-Rueda D, Ronfani L, Roshandel G, Roth G, Rothenbacher D, Roy A, Sagar R, Sahathevan R, Sanabria J, Sanchez-Niño M, Santos I, Santos J, Sarmiento-Suarez R, Sartorius B, Satpathy M, Savic M, Sawhney M, Schaub M, Schmidt M, Schneider I, Schöttker B, Schwebel D, Scott J, Seedat S, Sepanlou S, Servan-Mori E, Shackelford K, Shaheen A, Shaikh M, Sharma R, Sharma U, Shen J, Shepard D, Sheth K, Shibuya K, Shin M, Shiri R, Shiue I, Shrime M, Sigfusdottir I, Silva D, Silveira D, Singh A, Singh J, Singh O, Singh P, Sivonda A, Skirbekk V, Skogen J, Sligar A, Sliwa K, Soljak M, Søreide K, Sorensen R, Soriano J, Sposato L, Sreeramareddy C, Stathopoulou V, Steel N, Stein D, Steiner T, Steinke S, Stovner L, Stroumpoulis K, Sunguya B, Sur P, Swaminathan S, Sykes B, Szoeke C, Tabarés-Seisdedos R, Takala J, Tandon N, Tanne D, Tavakkoli M, Taye B, Taylor H, Ao B, Tedla B, Terkawi A, Thomson A, Thorne-Lyman A, Thrift A, Thurston G, Tobe-Gai R, Tonelli M, Topor-Madry R, Topouzis F, Tran B, Truelsen T, Dimbuene Z, Tsilimbaris M, Tura A, Tuzcu E, Tyrovolas S, Ukwaja K, Undurraga E, Uneke C, Uthman O, van Gool C, Varakin Y, Vasankari T, Venketasubramanian N, Verma R, Violante F, Vladimirov S, Vlassov V, Vollset S, Wagner G, Waller S, Wang L, Watkins D, Weichenthal S, Weiderpass E, Weintraub R, Werdecker A, Westerman R, White R, Williams H, Wiysonge C, Wolfe C, Won S, Woodbrook R, Wubshet M, Xavier D, Xu G, Yadav A, Yan L, Yano Y, Yaseri M, Ye P, Yebyo H, Yip P, Yonemoto N, Yoon S, Younis M, Yu C, Zaidi Z, Zaki M, Zeeb H, Zhou M, Zodpey S, Zuhlke L, Murray C. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet 2016, 388: 1545-1602. PMID: 27733282, PMCID: PMC5055577, DOI: 10.1016/s0140-6736(16)31678-6.Peer-Reviewed Original ResearchConceptsNon-communicable diseasesDisMod-MR 2.1Iron deficiency anemiaNon-fatal outcomesHIV/AIDSGBD 2013Global burdenStudy 2015Risk Factors Study 2015Bayesian meta-regression toolTropical diseasesCentral Latin AmericaSense organ disordersUpper respiratory infectionDisease Study 2015Sequelae of diseaseTension-type headacheCause of yearsCombinations of prevalenceYears of lifePermanent cariesGBD studyNeck painGBD 2010Genital herpes
2015
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
Collaborators G, Vos T, Barber R, Bell B, Bertozzi-Villa A, Biryukov S, Bolliger I, Charlson F, Davis A, Degenhardt L, Dicker D, Duan L, Erskine H, Feigin V, Ferrari A, Fitzmaurice C, Fleming T, Graetz N, Guinovart C, Haagsma J, Hansen G, Hanson S, Heuton K, Higashi H, Kassebaum N, Kyu H, Laurie E, Liang X, Lofgren K, Lozano R, MacIntyre M, Moradi-Lakeh M, Naghavi M, Nguyen G, Odell S, Ortblad K, Roberts D, Roth G, Sandar L, Serina P, Stanaway J, Steiner C, Thomas B, Vollset S, Whiteford H, Wolock T, Ye P, Zhou M, Ãvila M, Aasvang G, Abbafati C, Ozgoren A, Abd-Allah F, Aziz M, Abera S, Aboyans V, Abraham J, Abraham B, Abubakar I, Abu-Raddad L, Abu-Rmeileh N, Aburto T, Achoki T, Ackerman I, Adelekan A, Ademi Z, Adou A, Adsuar J, Arnlov J, Agardh E, Al Khabouri M, Alam S, Alasfoor D, Albittar M, Alegretti M, Aleman A, Alemu Z, Alfonso-Cristancho R, Alhabib S, Ali R, Alla F, Allebeck P, Allen P, AlMazroa M, Alsharif U, Alvarez E, Alvis-Guzman N, Ameli O, Amini H, Ammar W, Anderson B, Anderson H, Antonio C, Anwari P, Apfel H, Arsenijevic V, Artaman A, Asghar R, Assadi R, Atkins L, Atkinson C, Badawi A, Bahit M, Bakfalouni T, Balakrishnan K, Balalla S, Banerjee A, Barker-Collo S, Barquera S, Barregard L, Barrero L, Basu S, Basu A, Baxter A, Beardsley J, Bedi N, Beghi E, Bekele T, Bell M, Benjet C, Bennett D, Bensenor I, Benzian H, Bernabe E, Beyene T, Bhala N, Bhalla A, Bhutta Z, Bienhoff K, Bikbov B, Bin Abdulhak A, Blore J, Blyth F, Bohensky M, Basara B, Borges G, Bornstein N, Bose D, Boufous S, Bourne R, Boyers L, Brainin M, Brauer M, Brayne C, Brazinova A, Breitborde N, Brenner H, Briggs A, Brooks P, Brown J, Brugha T, Buchbinder R, Buckle G, Bukhman G, Bulloch A, Burch M, Burnett R, Cardenas R, Cabral N, Nonato I, Campuzano J, Carapetis J, Carpenter D, Caso V, Castaneda-Orjuela C, Catala-Lopez F, Chadha V, Chang J, Chen H, Chen W, Chiang P, Chimed-Ochir O, Chowdhury R, Christensen H, Christophi C, Chugh S, Cirillo M, Coggeshall M, Cohen A, Colistro V, Colquhoun S, Contreras A, Cooper L, Cooper C, Cooperrider K, Coresh J, Cortinovis M, Criqui M, Crump J, Cuevas-Nasu L, Dandona R, Dandona L, Dansereau E, Dantes H, Dargan P, Davey G, Davitoiu D, Dayama A, De la Cruz-Gongora V, de la Vega S, De Leo D, del Pozo-Cruz B, Dellavalle R, Deribe K, Derrett S, Jarlais D, Dessalegn M, deVeber G, Dharmaratne S, Diaz-Torne C, Ding E, Dokova K, Dorsey E, Driscoll T, Duber H, Durrani A, Edmond K, Ellenbogen R, Endres M, Ermakov S, Eshrati B, Esteghamati A, Estep K, Fahimi S, Farzadfar F, Fay D, Felson D, Fereshtehnejad S, Fernandes J, Ferri C, Flaxman A, Foigt N, Foreman K, Fowkes F, Franklin R, Furst T, Futran N, Gabbe B, Gankpe F, Garcia-Guerra F, Geleijnse J, Gessner B, Gibney K, Gillum R, Ginawi I, Giroud M, Giussani G, Goenka S, Goginashvili K, Gona P, de Cosio T, Gosselin R, Gotay C, Goto A, Gouda H, Guerrant R, Gugnani H, Gunnell D, Gupta R, Gupta R, Gutierrez R, Hafezi-Nejad N, Hagan H, Halasa Y, Hamadeh R, Hamavid H, Hammami M, Hankey G, Hao Y, Harb H, Haro J, Havmoeller R, Hay R, Hay S, Hedayati M, Pi I, Heydarpour P, Hijar M, Hoek H, Hoffman H, Hornberger J, Hosgood H, Hossain M, Hotez P, Hoy D, Hsairi M, Hu H, Hu G, Huang J, Huang C, Huiart L, Husseini A, Iannarone M, Iburg K, Innos K, Inoue M, Jacobsen K, Jassal S, Jeemon P, Jensen P, Jha V, Jiang G, Jiang Y, Jonas J, Joseph J, Juel K, Kan H, Karch A, Karimkhani C, Karthikeyan G, Katz R, Kaul A, Kawakami N, Kazi D, Kemp A, Kengne A, Khader Y, Khalifa S, Khan E, Khan G, Khang Y, Khonelidze I, Kieling C, Kim D, Kim S, Kimokoti R, Kinfu Y, Kinge J, Kissela B, Kivipelto M, Knibbs L, Knudsen A, Kokubo Y, Kosen S, Kramer A, Kravchenko M, Krishnamurthi R, Krishnaswami S, Defo B, Bicer B, Kuipers E, Kulkarni V, Kumar K, Kumar G, Kwan G, Lai T, Lalloo R, Lam H, Lan Q, Lansingh V, Larson H, Larsson A, Lawrynowicz A, Leasher J, Lee J, Leigh J, Leung R, Levi M, Li B, Li Y, Li Y, liang J, Lim S, Lin H, Lind M, Lindsay M, Lipshultz S, Liu S, Lloyd B, Ohno S, Logroscino G, Looker K, Lopez A, Lopez-Olmedo N, Lortet-Tieulent J, Lotufo P, Low N, Lucas R, Lunevicius R, Lyons R, Ma J, Ma S, Mackay M, Majdan M, Malekzadeh R, Mapoma C, Marcenes W, March L, Margono C, Marks G, Marzan M, Masci J, Mason-Jones A, Matzopoulos R, Mayosi B, Mazorodze T, McGill N, McGrath J, McKee M, McLain A, McMahon B, Meaney P, Mehndiratta M, Mejia-Rodriguez F, Mekonnen W, Melaku Y, Meltzer M, Memish Z, Mensah G, Meretoja A, Mhimbira F, Micha R, Miller T, Mills E, Mitchell P, Mock C, Moffitt T, Ibrahim N, Mohammad K, Mokdad A, Mola G, Monasta L, Montico M, Montine T, Moore A, Moran A, Morawska L, Mori R, Moschandreas J, Moturi W, Moyer M, Mozaffarian D, Mueller U, Mukaigawara M, Murdoch M, Murray J, Murthy K, Naghavi P, Nahas Z, Naheed A, Naidoo K, Naldi L, Nand D, Nangia V, Narayan K, Nash D, Nejjari C, Neupane S, Newman L, Newton C, Ng M, Ngalesoni F, Nhung N, Nisar M, Nolte S, Norheim O, Norman R, Norrving B, Nyakarahuka L, Oh I, Ohkubo T, Omer S, Opio J, Ortiz A, Pandian J, Panelo C, Papachristou C, Park E, Parry C, Caicedo A, Patten S, Paul V, Pavlin B, Pearce N, Pedraza L, Pellegrini C, Pereira D, Perez-Ruiz F, Perico N, Pervaiz A, Pesudovs K, Peterson C, Petzold M, Phillips M, Phillips D, Phillips B, Piel F, Plass D, Poenaru D, Polanczyk G, Polinder S, Pope C, Popova S, Poulton R, Pourmalek F, Prabhakaran D, Prasad N, Qato D, Quistberg D, Rafay A, Rahimi K, Rahimi-Movaghar V, Rahman S, Raju M, Rakovac I, Rana S, Razavi H, Refaat A, Rehm J, Remuzzi G, Resnikoff S, Ribeiro A, Riccio P, Richardson L, Richardus J, Riederer A, Robinson M, Roca A, Rodriguez A, Rojas-Rueda D, Ronfani L, Rothenbacher D, Roy N, Ruhago G, Sabin N, Sacco R, Ksoreide K, Saha S, Sahathevan R, Sahraian M, Sampson U, Sanabria J, Sanchez-Riera L, Santos I, Satpathy M, Saunders J, Sawhney M, Saylan M, Scarborough P, Schoettker B, Schneider I, Schwebel D, Scott J, Seedat S, Sepanlou S, Serdar B, Servan-Mori E, Shackelford K, Shaheen A, Shahraz S, Levy T, Shangguan S, She J, Sheikhbahaei S, Shepard D, Shi P, Shibuya K, Shinohara Y, Shiri R, Shishani K, Shiue I, Shrime M, Sigfusdottir I, Silberberg D, Simard E, Sindi S, Singh J, Singh L, Skirbekk V, Sliwa K, Soljak M, Soneji S, Soshnikov S, Speyer P, Sposato L, Sreeramareddy C, Stoeckl H, Stathopoulou V, Steckling N, Stein M, Stein D, Steiner T, Stewart A, Stork E, Stovner L, Stroumpoulis K, Sturua L, Sunguya B, Swaroop M, Sykes B, Tabb K, Takahashi K, Tan F, Tandon N, Tanne D, Tanner M, Tavakkoli M, Taylor H, Ao B, Temesgen A, Have M, Tenkorang E, Terkawi A, Theadom A, Thomas E, Thorne-Lyman A, Thrift A, Tleyjeh I, Tonelli M, Topouzis F, Towbin J, Toyoshima H, Traebert J, Tran B, Trasande L, Trillini M, Truelsen T, Trujillo U, Tsilimbaris M, Tuzcu E, Ukwaja K, Undurraga E, Uzun S, van Brakel W, van de Vijver S, Van Dingenen R, van Gool C, Varakin Y, Vasankari T, Vavilala M, Veerman L, Velasquez-Melendez G, Venketasubramanian N, Vijayakumar L, Villalpando S, Violante F, Vlassov V, Waller S, Wallin M, Wan X, Wang L, Wang J, Wang Y, Warouw T, Weichenthal S, Weiderpass E, Weintraub R, Werdecker A, Wessells K, Westerman R, Wilkinson J, Williams H, Williams T, Woldeyohannes S, DA Wolfe C, Wong J, Wong H, Woolf A, Wright J, Wurtz B, Xu G, Yang G, Yano Y, Yenesew M, Yentur G, Yip P, Yonemoto N, Yoon S, Younis M, Yu C, Kim K, Zaki M, Zhang Y, Zhao Z, Zhao Y, Zhu J, Zonies D, Zunt J, Salomon J, Murray C. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet 2015, 386: 743-800. PMID: 26063472, PMCID: PMC4561509, DOI: 10.1016/s0140-6736(15)60692-4.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAge DistributionAgedAged, 80 and overChildChild, PreschoolChronic DiseaseCost of IllnessDeveloped CountriesDeveloping CountriesDisabled PersonsFemaleGlobal HealthHumansIncidenceInfantInfant, NewbornMaleMiddle AgedNeglected DiseasesPrevalenceResidence CharacteristicsSex DistributionWounds and InjuriesYoung AdultConceptsCauses of YLDsNumber of sequelaeDisease Study 2013Permanent cariesInjury incidenceChronic diseasesGlobal burdenBayesian meta-regression methodGBD 2010 methodsRate of YLDsDisability-adjusted life yearsUpper respiratory infectionPopulation-based survey dataLow back painChronic respiratory diseasesSequelae of diseaseAge-standardised ratesMajor depressive disorderTension-type headacheNon-communicable diseasesNon-fatal outcomesMajor cause groupsShort-term injurySubstance use disordersHIV/AIDS
2012
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, AlMazroa M, Alvarado M, Anderson H, Anderson L, Andrews K, Atkinson C, Baddour L, Bahalim A, Barker-Collo S, Barrero L, Bartels D, Basáñez M, Baxter A, Bell M, Benjamin E, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black J, Blencowe H, Blore J, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha T, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke C, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter C, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng A, Chou D, Chugh S, Coffeng L, Colan S, Colquhoun S, Colson K, Condon J, Connor M, Cooper L, Corriere M, Cortinovis M, de Vaccaro K, Couser W, Cowie B, Criqui M, Cross M, Dabhadkar K, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Jarlais D, Dharmaratne S, Dherani M, Diaz-Torne C, Dolk H, Dorsey E, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali S, Erskine H, Erwin P, Espindola P, Ewoigbokhan S, Farzadfar F, Feigin V, Felson D, Ferrari A, Ferri C, Fèvre E, Finucane M, Flaxman S, Flood L, Foreman K, Forouzanfar M, Fowkes F, Franklin R, Fransen M, Freeman M, Gabbe B, Gabriel S, Gakidou E, Ganatra H, Garcia B, Gaspari F, Gillum R, Gmel G, Gosselin R, Grainger R, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa Y, Hall W, Haring D, Haro J, Harrison J, Havmoeller R, Hay R, Higashi H, Hill C, Hoen B, Hoffman H, Hotez P, Hoy D, Huang J, Ibeanusi S, Jacobsen K, James S, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas J, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo J, King C, Knowlton L, Kobusingye O, Koranteng A, Krishnamurthi R, Lalloo R, Laslett L, Lathlean T, Leasher J, Lee Y, Leigh J, Lim S, Limb E, Lin J, Lipnick M, Lipshultz S, Liu W, Loane M, Ohno S, Lyons R, Ma J, Mabweijano J, MacIntyre M, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis D, Marks G, Marks R, Matsumori A, Matzopoulos R, Mayosi B, McAnulty J, McDermott M, McGill N, McGrath J, Medina-Mora M, Meltzer M, Memish Z, Mensah G, Merriman T, Meyer A, Miglioli V, Miller M, Miller T, Mitchell P, Mocumbi A, Moffitt T, Mokdad A, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch M, Mwaniki M, Naidoo K, Nair M, Naldi L, Narayan K, Nelson P, Nelson R, Nevitt M, Newton C, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer S, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian J, Rivero A, Patten S, Pearce N, Padilla R, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips M, Pierce K, Pion S, Polanczyk G, Polinder S, Pope C, Popova S, Porrini E, Pourmalek F, Prince M, Pullan R, Ramaiah K, Ranganathan D, Razavi H, Regan M, Rehm J, Rein D, Remuzzi G, Richardson K, Rivara F, Roberts T, Robinson C, De Leòn F, Ronfani L, Room R, Rosenfeld L, Rushton L, Sacco R, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel D, Scott J, Segui-Gomez M, Shahraz S, Shepard D, Shin H, Shivakoti R, Silberberg D, Singh D, Singh G, Singh J, Singleton J, Sleet D, Sliwa K, Smith E, Smith J, Stapelberg N, Steer A, Steiner T, Stolk W, Stovner L, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor H, Taylor J, Taylor W, Thomas B, Thomson W, Thurston G, Tleyjeh I, Tonelli M, Towbin J, Truelsen T, Tsilimbaris M, Ubeda C, Undurraga E, van der Werf M, van Os J, Vavilala M, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall D, Weinstock M, Weintraub R, Weisskopf M, Weissman M, White R, Whiteford H, Wiersma S, Wilkinson J, Williams H, Williams S, Witt E, Wolfe F, Woolf A, Wulf S, Yeh P, Zaidi A, Zheng Z, Zonies D, Lopez A, Murray C. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 2012, 380: 2163-2196. PMID: 23245607, PMCID: PMC6350784, DOI: 10.1016/s0140-6736(12)61729-2.Peer-Reviewed Original ResearchConceptsNon-fatal health outcomesHealth outcomesHealth systemGlobal burdenMusculoskeletal disordersBayesian meta-regression methodChronic obstructive pulmonary diseasePopulation-based cancer registriesCauses of YLDsRate of YLDsHealth lossObstructive pulmonary diseaseDisease Study 2010Ambulatory care dataLow back painHospital discharge dataAge-specific prevalenceIron deficiency anemiaMajor depressive disorderBehavioral disordersDescriptive epidemiological dataLarge methodological variationNatural history modelYears of lifeHIV/AIDSDisability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, AlMazroa M, Alvarado M, Anderson H, Anderson L, Andrews K, Atkinson C, Baddour L, Bahalim A, Barker-Collo S, Barrero L, Bartels D, Basáñez M, Baxter A, Bell M, Benjamin E, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black J, Blencowe H, Blore J, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha T, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke C, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter C, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng A, Chou D, Chugh S, Coffeng L, Colan S, Colquhoun S, Colson K, Condon J, Connor M, Cooper L, Corriere M, Cortinovis M, de Vaccaro K, Couser W, Cowie B, Criqui M, Cross M, Dabhadkar K, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Jarlais D, Dharmaratne S, Dherani M, Diaz-Torne C, Dolk H, Dorsey E, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali S, Erskine H, Erwin P, Espindola P, Ewoigbokhan S, Farzadfar F, Feigin V, Felson D, Ferrari A, Ferri C, Fèvre E, Finucane M, Flaxman S, Flood L, Foreman K, Forouzanfar M, Fowkes F, Fransen M, Freeman M, Gabbe B, Gabriel S, Gakidou E, Ganatra H, Garcia B, Gaspari F, Gillum R, Gmel G, Gonzalez-Medina D, Gosselin R, Grainger R, Grant B, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa Y, Hall W, Haring D, Haro J, Harrison J, Havmoeller R, Hay R, Higashi H, Hill C, Hoen B, Hoffman H, Hotez P, Hoy D, Huang J, Ibeanusi S, Jacobsen K, James S, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas J, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo J, King C, Knowlton L, Kobusingye O, Koranteng A, Krishnamurthi R, Laden F, Lalloo R, Laslett L, Lathlean T, Leasher J, Lee Y, Leigh J, Levinson D, Lim S, Limb E, Lin J, Lipnick M, Lipshultz S, Liu W, Loane M, Ohno S, Lyons R, Mabweijano J, MacIntyre M, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis D, Marks G, Marks R, Matsumori A, Matzopoulos R, Mayosi B, McAnulty J, McDermott M, McGill N, McGrath J, Medina-Mora M, Meltzer M, Memish Z, Mensah G, Merriman T, Meyer A, Miglioli V, Miller M, Miller T, Mitchell P, Mock C, Mocumbi A, Moffitt T, Mokdad A, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch M, Mwaniki M, Naidoo K, Nair M, Naldi L, Narayan K, Nelson P, Nelson R, Nevitt M, Newton C, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer S, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian J, Rivero A, Patten S, Pearce N, Padilla R, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips M, Pierce K, Pion S, Polanczyk G, Polinder S, Pope C, Popova S, Porrini E, Pourmalek F, Prince M, Pullan R, Ramaiah K, Ranganathan D, Razavi H, Regan M, Rehm J, Rein D, Remuzzi G, Richardson K, Rivara F, Roberts T, Robinson C, De Leòn F, Ronfani L, Room R, Rosenfeld L, Rushton L, Sacco R, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel D, Scott J, Segui-Gomez M, Shahraz S, Shepard D, Shin H, Shivakoti R, Silberberg D, Singh D, Singh G, Singh J, Singleton J, Sleet D, Sliwa K, Smith E, Smith J, Stapelberg N, Steer A, Steiner T, Stolk W, Stovner L, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor H, Taylor J, Taylor W, Thomas B, Thomson W, Thurston G, Tleyjeh I, Tonelli M, Towbin J, Truelsen T, Tsilimbaris M, Ubeda C, Undurraga E, van der Werf M, van Os J, Vavilala M, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall D, Weinstock M, Weintraub R, Weisskopf M, Weissman M, White R, Whiteford H, Wiebe N, Wiersma S, Wilkinson J, Williams H, Williams S, Witt E, Wolfe F, Woolf A, Wulf S, Yeh P, Zaidi A, Zheng Z, Zonies D, Lopez A. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 2012, 380: 2197-2223. PMID: 23245608, DOI: 10.1016/s0140-6736(12)61689-4.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsGlobal disability-adjusted life yearsDisease burdenNon-communicable diseasesGlobal burdenDisability weightsCrude disability-adjusted life yearLife yearsCauses of DALYsNew disability weightsLower respiratory infectionsDisease Study 2010Ischemic heart diseaseSum of yearsNutritional disordersCause-specific mortalityMajor depressive disorderGlobal disease burdenHIV/AIDSContribution of deathsCause mortalityRespiratory infectionsSaharan AfricaInjury burdenHeart disease